Results 231 to 240 of about 89,290 (305)

Ultra‐Low Intensity Continuous Wave Laser Ablation Propulsion With Graphene‐Engineered Wood

open access: yesAdvanced Science, EarlyView.
Graphene delignified wood converts continuous wave laser energy into thrust. Laser propulsion experiments in vacuum reveal the lowest laser ablation threshold intensities and the greatest density‐normalized specific impulse in literature. The results highlight graphene delignified wood as a potential efficient, sustainable, strong, and lightweight ...
Afnan S. M. Elmubasher   +10 more
wiley   +1 more source

Genomic analysis of Canadian children with food allergies points to the immunoglobulin heavy chain gene locus. [PDF]

open access: yesPediatr Allergy Immunol
Madore AM   +11 more
europepmc   +1 more source

Integrated Single‐Cell and Spatial Analysis Reveals a Metabolic‐Immune Axis Driving Aortic Dissection

open access: yesAdvanced Science, EarlyView.
Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao   +25 more
wiley   +1 more source

Light‐Switched Mesenchymal Stem Cells for In Situ Exosome Amplification in Craniofacial Bone Defect Reconstruction

open access: yesAdvanced Science, EarlyView.
Light‐switchable MSCs (MSC‐UCNPs) were constructed by intracellular incorporation of UCNPs. Upon 980 nm irradiation, UCNPs emitted localized ultraviolet light (365 nm), activating the ROS/HEXB/LAMP1 signaling pathway to suppress lysosome–multivesicular body fusion and thereby enhance exosome biogenesis. Embedded within an injectable hydrogel, MSC‐UCNPs
Tingting Wu   +7 more
wiley   +1 more source

Conformation-aware structure prediction of antigen-recognizing immune proteins. [PDF]

open access: yesMAbs
Dreyer FA   +10 more
europepmc   +1 more source

High‐Performance Prevascularized SHED‐Laden rGO@Hydrogel Achieves Optimized Diabetic Bone Defect Repair

open access: yesAdvanced Science, EarlyView.
A high‐performance 3D scaffold integrating rGO and SHEDs is developed to overcome impaired healing in diabetic bone defects. By driving extracellular matrix remodeling, rGO creates a pro‐angiogenic niche that significantly accelerates in vitro vascular network formation.
Can Zhang   +12 more
wiley   +1 more source

NGS-based measurable residual disease in long-term progression-free CLL survivors following FCR therapy. [PDF]

open access: yesBlood Adv
Bazinet A   +9 more
europepmc   +1 more source

Drug‐Induced Cuproptosis Defines the Therapeutic Window of Celecoxib in Intervertebral Disc Degeneration via the HSP90‐RBX1 Axis

open access: yesAdvanced Science, EarlyView.
This study reveals the dual role of celecoxib in intervertebral disc degeneration. While low concentrations are protective, high concentrations induce toxicity by upregulating HSP90, which synergizes with USP15 to deubiquitinate and stabilize RBX1. This leads to degradation of COMMD1/ATP7B, copper dyshomeostasis, and ultimately, cuproptosis.
Youfeng Guo   +11 more
wiley   +1 more source

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