Results 61 to 70 of about 182,946 (270)
INDICES OF IMMUNE RESPONSE IN PATIENTS OF FALCIPARUM MALARIA IN REPUBLIC OF GUINEA
Инфекция и иммунитет, 2016 Malaria in the Republic of Guinea is the main cause of morbidity and lethality. It takes the first place in number of all visits in medical service (30–40%) and is the main cause of hospital death. One records annually more than 8 millions malaria cases,
M. Y. Boiro +5 more
doaj +1 more source
Immunoglobulins, Mucosal Immunity and Vaccination in Teleost Fish
Frontiers in Immunology, 2020 Due to direct contact with aquatic environment, mucosal surfaces of teleost fish are continuously exposed to a vast number of pathogens and also inhabited by high densities of commensal microbiota.
Yongyao Yu +6 more
doaj +1 more source
A Low-temperature 1H NMR Study of H2O and D2O Associated Competitively with Immunoglobulin G in Solution [PDF]
arXiv, 2007 An approach has been proposed to characterize the competitive association of D2O and to study the heterogeneity of hydration water adsorbed by the protein, immunoglobulin G, using methodology for determining of non-freezing water in mixed H2O-D2O protein solutions by low-temperature 1H NMR technique. Direct data on the numbers of deuteriums adsorbed by
arxiv
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Molecular Oncology, EarlyView.Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
THE FEATURES OF BLOOD IMMUNOLOGICAL PARAMETERS IN PATIENTS WITH VARIOUS FORMS OF BRUCELLOSIS
Инфекция и иммунитет, 2014 . Results of current study have shown that acute brucellosis is characterized by increase of T-helper and cytotoxic T-lymphocytes and decrease of phagocytic activity of neutrophyls in the blood.
O. V. Logvinenko +5 more
doaj +1 more source
Thrombocytopenia in the Course of COVID-19 Infection
European Journal of Case Reports in Internal Medicine, 2020 We report three cases of severe thrombocytopenia during COVID-19 infection associated with either cutaneous purpura or mucosal bleeding. The initial investigations ruled out other causes of thrombocytopenia.
Noel Lorenzo-Villalba +7 more
doaj +1 more source
Attractors in residual interactions explain the differentially-conserved stability of Immunoglobulins [PDF]
arXiv, 2014 Proteins belonging to immunoglobulin superfamily(IgSF) show remarkably conserved nature both in their folded structure and in their folding process, but they neither originate from very similar sequences nor demonstrate functional conservation. Treating proteins as fractal objects, without studying spatial conservation in positioning of particular ...
arxiv
FEBS Open Bio, EarlyView.Novel mAbs could detect cancer‐associated membrane proteins on various type of pancreatic ductal adenocarcinomas (PDAC) by flow cytometry with viable PDAC cells and by immunohistochemistry with PDAC tissues. Results of protein expression were substantiated by mRNA expression by The Cancer Genome Atlas.
Takashi Nakano +16 more
wiley +1 more source
Study on Antibody-Virus Interaction using Molecular Dynamics: Two Dimensional Simulation on Immunoglobulin Reaction against Human Papillomavirus [PDF]
arXiv, 2013 Human Papillomavirus (HPV) has been known as one of the cause of virus-induced cancer such as cervical cancer and carcinoma. Among other types of cancer, this type has higher chance in being prevented earlier. The main idea is to eradicate the virus as soon as it enters the body by marking it with antibodies; signaling the immune system to dispose of ...
arxiv
FEBS Open Bio, EarlyView.By using an electrical pulse stimulation (EPS)‐based in vitro exercise model and chemical activation/inhibition of mechanosensitive Piezo1 channels, we explored changes in protein synthetic response in cultured C2C12 myotubes. Our data showed that application of Piezo1 activator (Yoda1) during EPS significantly enhances the rate of protein synthesis in
Natalia A. Vilchinskaya +3 more
wiley +1 more source