Results 11 to 20 of about 1,228,272 (336)

Syndecan-2 is a novel target of insulin-like growth factor binding protein-3 and is over-expressed in fibrosis [PDF]

, 2012
Extracellular matrix deposition and tissue scarring characterize the process of fibrosis. Transforming growth factor beta (TGFβ) and Insulin-like growth factor binding protein-3 (IGFBP-3) have been implicated in the pathogenesis of fibrosis in various ...
Adriana T. Larregina, Carol A. Feghali-Bostwick, Joseph M. Pilewski, Logan R. Mlakar, Sebastien Fuchs, Ximena D. Ruiz, Yukie Yamaguchi, Yunyun Su   +7 more
core   +7 more sources

Is the biology of breast cancer changing? A study of hormone receptor status 1984-1986 and 1996-1997 [PDF]

, 2009
Using archived tumours, those from 1984-1986 and 1996-1997 underwent immunohistochemistry for hormone receptors and grade analysis. A significant shift towards more ER-positive and low-grade disease was found; this appears to reflect screening practices,
AG Glass, B Elsberger, CI Li, CS Thomson, E A Mallon, F M Campbell, GA Colditz, J Edwards, JD Potter, L M McGlynn, L Tabar, MJ Bradburn, P Pujol, S B F Brown, SBF Brown, T G Cooke, T Kirkegaard   +16 more
core   +2 more sources

Immunohistochemistry

Journal of Pathology of Nepal, 2015
Immunohistochemistry (IHC) or immunocytochemistry is a method of localizing specific antigen in tissue or cells based on antigen antibody reaction. IHC is the way of validating morphological findings. It helps in tumor diagnosis and classification, identify prognostic and predictive markers.
Clive R. Taylor, Richard J. Cote
  +7 more sources

Rapid micro-immunohistochemistry [PDF]

Microsystems & Nanoengineering, 2020
AbstractWe present a new and versatile implementation of rapid and localized immunohistochemical staining of tissue sections. Immunohistochemistry (IHC) comprises a sequence of specific biochemical reactions and allows the detection of specific proteins in tissue sections.
Robert D. Lovchik, David Taylor, Govind Kaigala   +2 more
openaire   +5 more sources

The Tumor Suppressor HHEX Inhibits Axon Growth when Prematurely Expressed in Developing Central Nervous System Neurons [PDF]

, 2015
Neurons in the embryonic and peripheral nervoussystem respond to injury by activating transcriptional programs supportive of axon growth, ultimately resulting in functional recovery.
Blackmore, Murray G., Callif, Ben L., Coley, Denise M., Kramer, Audra A., Lerch, Jessica K., Simpson, Matthew T., Thiel, Laura K., Venkatesh, Ishwariya, Wang, Zimei, Winsor, Kristen N.   +9 more
core   +2 more sources

The Society for Immunotherapy in Cancer statement on best practices for multiplex immunohistochemistry (IHC) and immunofluorescence (IF) staining and validation

Journal for ImmunoTherapy of Cancer, 2020
Objectives The interaction between the immune system and tumor cells is an important feature for the prognosis and treatment of cancer. Multiplex immunohistochemistry (mIHC) and multiplex immunofluorescence (mIF) analyses are emerging technologies that ...
J. Taube, Guray Akturk, Michael Angelo, Elizabeth L Engle, S. Gnjatic, Shirley Greenbaum, N. Greenwald, C. Hedvat, T. Hollmann, J. Juco, E. Parra, M. Rebelatto, D. Rimm, J. Rodriguez-Canales, K. Schalper, E. Stack, Cláudia S Ferreira, Konstanty Korski, Ana Lako, S. Rodig, Emanuel Schenck, K. Steele, M. Surace, M. Tetzlaff, Katharina von Loga, I. Wistuba, C. Bifulco   +26 more
semanticscholar   +1 more source

The XIIIth Banff Conference on Allograft Pathology: The Banff 2015 Heart Meeting Report: Improving Antibody-Mediated Rejection Diagnostics: Strengths, Unmet Needs, and Future Directions. [PDF]

, 2017
The 13th Banff Conference on Allograft Pathology was held in Vancouver, British Columbia, Canada from October 5 to 10, 2015. The cardiac session was devoted to current diagnostic issues in heart transplantation with a focus on antibody-mediated rejection
Angelini, A, Berry, GJ, Bruneval, P, Dragun, D, Duong Van Huyen, JP, Fedrigo, M, Haas, M, Loupy, A, Mengel, M, Miller, D, Potena, L, Reed, EF, Reinsmoen, N, Revelo, P, Smith, RN, Tebutt, S, Thum, T, West, L, Zeevi, A   +18 more
core   +1 more source

Semi-quantitative Determination of Protein Expression using Immunohistochemistry Staining and Analysis: An Integrated Protocol.

Bio-protocol, 2019
Semi-quantitative IHC is a powerful method for investigating protein expression and localization within tissues. The semi-quantitative immunohistochemistry (IHC) involves using software such as free software ImageJ Fiji to conduct deconvolution and ...
A. Crowe, W. Yue
semanticscholar   +1 more source

Application of Immunohistochemistry in the Pathological Diagnosis of Liver Tumors

International Journal of Molecular Sciences, 2021
Although radiological diagnostics have been progressing, pathological diagnosis remains the most reliable method for diagnosing liver tumors. In some cases, definite pathological diagnosis cannot be obtained by histological evaluation alone, especially ...
Yoshihisa Takahashi, Erdenetsogt Dungubat, Hiroyuki Kusano, Dariimaa Ganbat, Y. Tomita, Sarandelger Odgerel, T. Fukusato   +6 more
semanticscholar   +1 more source

Applications of immunohistochemistry

Journal of Pharmacy And Bioallied Sciences, 2012
Immunohistochemistry (IHC) is an important application of monoclonal as well as polyclonal antibodies to determine the tissue distribution of an antigen of interest in health and disease. IHC is widely used for diagnosis of cancers; specific tumor antigens are expressed de novo or up-regulated in certain cancers.
Rajeshwar Govindarajan, Murugesan Palanisamy, Jeyapradha Duraiyan, Karunakaran Kaliyappan   +3 more
openaire   +4 more sources