Results 21 to 30 of about 963,734 (335)

Collagenase-Induced Mouse Model of Osteoarthritis—A Thorough Flow Cytometry Analysis

Life, 2022
Objectives: Osteoarthritis (OA) is a chronic degenerative disorder of the joint characterized by cartilage breakdown and synovial inflammation.
Blagovesta Boneva, Nikola Ralchev, Petya Ganova, Andrey Tchorbanov, Nikolina Mihaylova   +4 more
doaj   +1 more source

Immunoexpression of stem cell markers SOX-2, NANOG AND OCT4 in ameloblastoma [PDF]

PeerJ, 2023
Background Ameloblastoma (AME) is characterized by a locally invasive growth pattern. In an attempt to justify the aggressiveness of neoplasms, the investigation of the role of stem cells has gained prominence.
Karolyny Martins Balbinot, Felippe José Almeida Loureiro, Giordanna Pereira Chemelo, Ricardo Alves Mesquita, Aline Maria Pereira Cruz Ramos, Rommel Thiago Jucá Ramos, Artur Luiz da Costa da Silva, Sílvio Augusto Fernandes de Menezes, Maria Sueli da Silva Kataoka, Sergio de Melo Alves Junior, João de Jesus Viana Pinheiro   +10 more
doaj   +2 more sources

Muscle hypertrophy and ladder‐based resistance training for rodents: A systematic review and meta‐analysis

Physiological Reports, 2020
This study aimed to review the effects of ladder‐based resistance training (LRT) on muscle hypertrophy and strength in rodents through a systematic review with meta‐analysis. We systematically searched PubMed/Medline, SportDiscuss, Scopus, Google Scholar,
Ítalo Lourenço, Walter Krause Neto, Laura dosSantos Portella Amorim, Vagner Moraes Munhoz Ortiz, Vitor Lopes Geraldo, Gabriel Henrique da Silva Ferreira, Érico Chagas Caperuto, Eliane Florencio Gama   +7 more
doaj   +1 more source

Crosstalk Between DNA Methylation and Gene Mutations in Colorectal Cancer

Frontiers in Oncology, 2021
Colorectal cancer (CRC) is often characterized by mutations and aberrant DNA methylation within the promoters of tumor suppressor genes and proto-oncogenes. The most frequent somatic mutations occur within KRAS and BRAF genes.
Maria Dobre, Alessandro Salvi, Iulia Andreea Pelisenco, Florina Vasilescu, Giuseppina De Petro, Vlad Herlea, Elena Milanesi   +6 more
doaj   +1 more source

Is the biology of breast cancer changing? A study of hormone receptor status 1984-1986 and 1996-1997 [PDF]

, 2009
Using archived tumours, those from 1984-1986 and 1996-1997 underwent immunohistochemistry for hormone receptors and grade analysis. A significant shift towards more ER-positive and low-grade disease was found; this appears to reflect screening practices,
AG Glass, B Elsberger, CI Li, CS Thomson, E A Mallon, F M Campbell, GA Colditz, J Edwards, JD Potter, L M McGlynn, L Tabar, MJ Bradburn, P Pujol, S B F Brown, SBF Brown, T G Cooke, T Kirkegaard   +16 more
core   +2 more sources

Crocus sativus Extract as a Biological Agent for Disease-Modifying Therapy of Collagenase-Induced Mouse Model of Osteoarthritis

Life, 2023
Objectives: Osteoarthritis (OA) is an age-related joint disease that involves the degeneration of cartilage and is the most prevalent form of arthritis, affecting a large part of the population.
Blagovesta Boneva, Andrey Marchev, Kristiana Amirova, Petya Ganova, Milen Georgiev, Andrey Tchorbanov, Nikolina Mihaylova   +6 more
doaj   +1 more source

The prognostic value of the hypoxia markers CA IX and GLUT 1 and the cytokines VEGF and IL 6 in head and neck squamous cell carcinoma treated by radiotherapy ± chemotherapy [PDF]

, 2005
BACKGROUND: Several parameters of the tumor microenvironment, such as hypoxia, inflammation and angiogenesis, play a critical role in tumor aggressiveness and treatment response.
A Dietz, CC Wykoff, DM Brizel, E Tartour, EP Hui, Erik Verbeken, H Mineta, Harlinde De Schutter, J Bussink, J Dunst, JA Forsythe, JH Kaanders, K Muraoka, Laurence Goethals, M Kunkel, M Nordsmark, MA St John, MI Koukourakis, P Mellanen, P Vaupel, R Airley, R Hermans, R Srivani, Robert Hermans, S Ivanov, S Pastorekova, Sandra Nuyts, T Tamatani, TN Teknos, V Brouazin-Jousseaume, V Michalaki, W Jelkmann, Willy Landuyt, Y Miyamoto, YC Chung, Z Chen   +35 more
core   +3 more sources

Aging Induces Changes in the Somatic Nerve and Postsynaptic Component without Any Alterations in Skeletal Muscles Morphology and Capacity to Carry Load of Wistar Rats

Frontiers in Neuroscience, 2017
The present study aimed to analyze the morphology of the peripheral nerve, postsynaptic compartment, skeletal muscles and weight-bearing capacity of Wistar rats at specific ages.
Walter Krause Neto, Wellington de Assis Silva, Adriano P. Ciena, Romeu R. de Souza, Carlos A. Anaruma, Eliane F. Gama   +5 more
doaj   +1 more source

Rapid micro-immunohistochemistry [PDF]

Microsystems & Nanoengineering, 2020
AbstractWe present a new and versatile implementation of rapid and localized immunohistochemical staining of tissue sections. Immunohistochemistry (IHC) comprises a sequence of specific biochemical reactions and allows the detection of specific proteins in tissue sections.
Robert D. Lovchik, David Taylor, Govind Kaigala   +2 more
openaire   +5 more sources

The Tumor Suppressor HHEX Inhibits Axon Growth when Prematurely Expressed in Developing Central Nervous System Neurons [PDF]

, 2015
Neurons in the embryonic and peripheral nervoussystem respond to injury by activating transcriptional programs supportive of axon growth, ultimately resulting in functional recovery.
Blackmore, Murray G., Callif, Ben L., Coley, Denise M., Kramer, Audra A., Lerch, Jessica K., Simpson, Matthew T., Thiel, Laura K., Venkatesh, Ishwariya, Wang, Zimei, Winsor, Kristen N.   +9 more
core   +2 more sources