Results 81 to 90 of about 1,287,734 (381)

Features of Appendix and the Characteristics of Appendicitis Development in Children with COVID-19

Biomedicines
Background: Research on the subject of the influence of SARS-CoV-2 mechanisms on human homeostasis remains an actual problem. Particular interest is the study of pathomorphological changes in the appendix in children with COVID-19.
Grigory Demyashkin, Konstantin Gorokhov, Vladimir Shchekin, Matvey Vadyukhin, Artem Matevosyan, Arina Rudavina, Anna Pilipchuk, Alina Pilipchuk, Svetlana Kochetkova, Dmitrii Atiakshin, Petr Shegay, Andrey Kaprin   +11 more
doaj   +1 more source

Immunohistochemistry for diagnosis and prognosis of breast cancer: a review

Biotechnic & Histochemistry, 2020
Breast cancer is the most prevalent malignant tumor and main oncologic cause of mortality in women. Although most diagnosis of breast pathology is accomplished using hematoxylin and eosin stained sections, some cases require immunohistochemistry for ...
T. Bonacho, Francisco Rodrigues, J. Liberal   +2 more
semanticscholar   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

Syndecan-2 is a novel target of insulin-like growth factor binding protein-3 and is over-expressed in fibrosis [PDF]

, 2012
Extracellular matrix deposition and tissue scarring characterize the process of fibrosis. Transforming growth factor beta (TGFβ) and Insulin-like growth factor binding protein-3 (IGFBP-3) have been implicated in the pathogenesis of fibrosis in various ...
Adriana T. Larregina, Carol A. Feghali-Bostwick, Joseph M. Pilewski, Logan R. Mlakar, Sebastien Fuchs, Ximena D. Ruiz, Yukie Yamaguchi, Yunyun Su   +7 more
core   +4 more sources

Role of immunohistochemistry in lymphoma

Indian Journal of Medical and Paediatric Oncology, 2010
Rao I
doaj   +4 more sources

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Wild Birds’ Genetic Resources Bank: Feather Follicle Cell Culture as a Possible Source of Stem Cells

Methods and Protocols
Follicular cells represent a valuable resource for genetic research, biotechnology and cryopreservation in biobanks, particularly for the conservation of endangered species.
Yasmin Godoi dos Reis, Maria Eduarda Pralon Guerra, Meline de Paula Coutinho, Sarah Ingrid Pinto Santos, Bruna Dias Mota, Lauriene Luiza de Souza Munhoz, Diogo Pascoal Rossetti, Daniele dos Santos Martins   +7 more
doaj   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

P53 mutations in human adrenocortical neoplasms [PDF]

, 1994
The mechanisms of tumorigenesis of adrenocortical neoplasms have not been elucidated as yet. However, loss of heterozygosity at chromosomal locus 17p has been consistently observed in adrenocortical cancer.
Allolio, B., Chrousos, G. P., Karl, M., Linehan, M., Mastorakis, G., Reincke, Martin, Travis, W.   +6 more
core  

Cop1 constitutively regulates c-Jun protein stability and functions as a tumor suppressor in mice [PDF]

, 2011
Biochemical studies have suggested conflicting roles for the E3 ubiquitin ligase constitutive photomorphogenesis protein 1 (Cop 1; also known as Rfwd2) in tumorigenesis, providing evidence for both the oncoprotein c-Jun and the tumor suppressor p53 as ...
Aleksandra Zwolinska, Angel, Baert, Bannister, Chang, Chen, Danovi, de Launoit, Dentin, Derijard, Dieter Defever, Domenico Migliorini, Dornan, Edwards, Eferl, Enrico Radaelli, Fuchs, Geertrui Denecker, Horn, Jean-Christophe Marine, Karin, Kato, Kominami, Krummel, Kyriakis, Lopez-Bergami, Mariani, Marine, Mendrysa, Morse HC, Nakayama, Ouyang, Qi, Rajesh Vyas, Ramaswamy, Rincon, Rossant, Schreiber, Sven Bogaerts, Tino Hochepied, Vanessa Depaepe, Wang, William C. Skarnes, Zhong   +43 more
core   +2 more sources