Results 71 to 80 of about 3,331 (204)

IMGT-ONTOLOGY for immunogenetics and immunoinformatics.

In silico biology, 2004
IMGT, the international ImMunoGeneTics information system(R) (http://imgt.cines.fr), is a high quality integrated knowledge resource specializing in immunoglobulins (IG), T cell receptors (TR), major histocompatibility complex (MHC) and related proteins of the immune system (RPI) of human and other vertebrates, created in 1989, by the Laboratoire d ...
Lefranc, Marie-Paule, Giudicelli, Véronique, Ginestoux, Chantal, Bosc, Nathalie, Folch, Géraldine, Guiraudou, Delphine, Jabado-Michaloud, Joumana, Magris, Séverine, Scaviner, Dominique, Thouvenin, Valérie, Combres, Kora, Girod, David, Jeanjean, Stéphanie, Protat, Céline, Yousfi-Monod, Mehdi, Duprat, Elodie, Kaas, Quentin, Pommié, Christelle, Chaume, Denys, Lefranc, Gérard   +19 more
openaire   +3 more sources

Plant‐Based Mycetoma Inhibitors Targeting the 50S Ribosomal Protein of Nocardia brasiliensis: In Silico Approach

ChemistrySelect, Volume 10, Issue 21, June 4, 2025.
In‐silico drug discovery pipeline for Mycetoma caused by Nocardia brasiliensis. A library of 1034 phytocompounds was screened to identify potent inhibitors, with Parviflorone F showing strong binding and stability against the 50S ribosomal unit. Molecular dynamics confirmed its inhibitory potential, offering a promising therapeutic candidate.
Sandra Jose, Manjunathan Jagadeesan, Meenambiga Setti Sudharsan, Pasiyappazham Ramasamy, Shyamala Gowri, Muthu Thiruvengadam, Sowmya Hari, Baskar Venkidasamy   +7 more
wiley   +1 more source

Marburg Virus Disease: A Narrative Review

Health Science Reports, Volume 8, Issue 5, May 2025.
ABSTRACT Background and Aims Given the recent deadly outbreaks of the Marburg virus (MARV), in early 2023 in Tanzania and Equatorial Guinea, and the most recent one in Rwanda in 2024, there has been renewed attention across Africa on the threat posed by the re‐emergence of MARV as a growing concern for public health.
Arash Letafati, Somayeh Sadat Hosseini Fakhr, Ali Qaraee Najafabadi, Negin Karami, Hassan Karami   +4 more
wiley   +1 more source

Immunoinformatics: Current trends and future directions

Drug Discovery Today, 2009
Immunoinformatics has recently emerged as a critical field for accelerating immunology research. Although still an evolving process, computational models now play instrumental roles, not only in directing the selection of key experiments, but also in the formulation of new testable hypotheses through detailed analysis of complex immunologic data that ...
Tong, J.C., Ren, E.C.
openaire   +2 more sources

Immunoinformatic Analysis of T- and B-Cell Epitopes for SARS-CoV-2 Vaccine Design

Vaccines, 2020
Currently, there is limited knowledge about the immunological profiles of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). We used computer-based immunoinformatic analysis and the newly resolved 3-dimensional (3D) structures of the SARS-CoV ...
Dongliang Wang, Jinhui Mai, Wenfeng Zhou, Wanting Yu, Yang Zhan, Naidong Wang, Neal D. Epstein, Yi Yang   +7 more
doaj   +1 more source

TRain: T-cell receptor automated immunoinformatics

BMC Bioinformatics
The scarcity of available structural data makes characterizing the binding of T-cell receptors (TCRs) to peptide-Major Histocompatibility Complexes (pMHCs) very challenging. The recent surge in sequencing data makes TCRs an ideal target for protein structure modeling. Through these 3D models, researchers can potentially identify key motifs on the TCR's
Austin Seamann, Maia Bennett-Boehm, Ryan Ehrlich, Anna Gil, Liisa Selin, Dario Ghersi   +5 more
openaire   +3 more sources

Immunoinformatic analysis of haemagglutinin-neuraminidase protein to reveal molecular immunogenicity of Newcastle disease virus between vaccine and Indonesian strain

Bulgarian Journal of Veterinary Medicine
Newcastle disease (ND) is a significant avian disease in Indonesia, causing substantial economic losses in poultry production. Despite vaccination efforts, ND outbreaks persist, raising questions about vaccine efficacy.
F. P. C. Santoso, L. Angeliya , M. H. Wibowo   +2 more
doaj   +1 more source

Exploring YidR Gene from Klebsiella pneumoniae To Design a Multi-epitope Vaccine Using Immunoinformatics Approach

, 2022
Maulana Wildan Seputra, Hani Susiati, Tri Yudani Mardining Raras, Tri Yudani Mardining Raras, Universitas Brawijaya   +4 more
openalex   +2 more sources

Designing of Potential Polyvalent Vaccine Model for Respiratory Syncytial Virus by System Level Immunoinformatics Approaches [PDF]

, 2021
Syeda Tahira Qousain Naqvi, Mamoona Yasmeen, Mehreen Ismail, Syed Aun Muhammad, Syed Nawazish-i-Husain, Amjad Ali, Fahad Munir, Qiyu Zhang   +7 more
openalex   +1 more source

Multiepitope-based vaccine design against DiiA in Streptococcus pneumoniae , An immunoinformatics approach [PDF]

, 2023
Mariam M. Soliman, Dania Sheikhani, Jihan Nassar, Sherif Elsabbagh, Tamer M. Ibrahim   +4 more
openalex   +1 more source