Results 51 to 60 of about 2,266 (210)
, 2021 Giardiasis is one of the most common gastrointestinal infections worldwide, mainly in developing countries. The etiological agent is the Giardia lamblia parasite.
Thania Garzon (11611648) +6 more
core +1 more source
Immunoinformatics and tick vaccinology
Exploration of Immunology, 2023 Immunoinformatics is an emerging area focused on development and applications of methods used to facilitate vaccine development. There is a growing interest in the field of vaccinology centered on the new omic science named ‘vaccinomics’. However, this approach has not succeeded to provide a solution against major infections affecting both animals and ...
Rodrigo Rosario-Cruz +3 more
openaire +1 more source
MicroorganismsDiagnosing canine visceral leishmaniasis (CVL) in Brazil faces challenges due to the limitations regarding the sensitivity and specificity of the current diagnostic protocol.
Gabriel Moreira +10 more
doaj +1 more source
The Advantage of Using Immunoinformatic Tools on Vaccine Design and Development for Coronavirus
, 2022 After the outbreak of SARS-CoV-2 by the end of 2019, the vaccine development strategies became a worldwide priority. Furthermore, the appearances of novel SARS-CoV-2 variants challenge researchers to develop new pharmacological or preventive strategies ...
José Correa-Basurto +7 more
core +1 more source
An Insight for the Future Development of Diagnostic Tool by Exploiting Novel Leishmania Donovani Recombinant Hypothetical Protein [PDF]
Journal of Clinical and Diagnostic Research, 2018 Introduction: Assenting diagnosis of Visceral Leishmaniasis (VL) relies on the detection of Leishmania donovani (L. donovani) in splenic and bone marrow specimens obtained by invasive techniques.
Fauzia Jamal +7 more
doaj +1 more source
Biotechnology and Applied Biochemistry, EarlyView.ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva +8 more
wiley +1 more source
Human Cytomegalovirus Genetic Diversity, Clinical Relevance, and Emerging Insights
Reviews in Medical Virology, Volume 36, Issue 5, September 2026.ABSTRACT Human cytomegalovirus (HCMV) is a globally prevalent virus that poses a significant public health concern, especially for newborns and immunocompromised patients, causing a wide range of infections. Clinical outcomes associated with HCMV infection include congenital disease, graft rejection in transplant recipients, and life‐threatening ...
Hajar Y. AlQahtani +2 more
wiley +1 more source
Edible Insect Allergens: An Emerging Food Safety Challenge
Sustainable Food Proteins, Volume 4, Issue 3, September 2026.Allergic responses to edible insects arise via two main pathways: cross‐reactivity with homologous arthropod allergens and primary sensitization to edible insect proteins, both leading to IgE‐mediated immune activation. ABSTRACT Edible insects are increasingly promoted as sustainable protein sources; however, their allergenic potential remains a ...
Changqi Liu +5 more
wiley +1 more source
Immunoinformatics and Vaccine Development: An Overview.
ImmunoTargets and therapy, 2020 The use of vaccines have resulted in a remarkable improvement in global health. It has saved several lives, reduced treatment costs and raised the quality of animal and human lives. Current traditional vaccines came empirically with either vague or completely no knowledge of how they modulate our immune system.
Oli,Angus Nnamdi +7 more
openaire +3 more sources
Immunoinformatic identification of CD8+ T-cell epitopes [PDF]
Antigen-specific T-cells play a crucial role in the adaptive immune response by providing a defence mechanism against pathogens and maintaining tolerance against self-antigens.
Lee, Hyun-Jung
core +1 more source