Results 21 to 30 of about 840,473 (392)
Vaccination for Respiratory Syncytial Virus: A Narrative Review and Primer for Clinicians
Vaccines, 2023 Respiratory syncytial virus (RSV) poses a significant burden on public health, causing lower respiratory tract infections in infants, young children, older adults, and immunocompromised individuals.
Kay Choong See
doaj +1 more source
Frontiers in Immunology, 2018 Accumulating evidence suggests important functions for human Toll-like receptor 8 in vivo in tuberculosis and autoimmune diseases. However, these studies are limited by the lack of specific agonists and by the fact that the homology of TLR8 in human and ...
Jun Tang +23 more
doaj +1 more source
Journal of Clinical Investigation, 1973 Endothelial cells were isolated from freshly obtained human umbilical cords by collagenase digestion of the interior of the umbilical vein. The cells were grown in tissue culture as a homogeneous population for periods up to 5 mo and some lines were ...
E. Jaffe +3 more
semanticscholar +1 more source
The Effects of Honey Sulfonamides on Immunological and Hematological Parameters in Wistar Rats
Medicina, 2022 Sulfonamides are among the most used drugs in beekeeping due to their effectiveness, despite their long-term persistence in tissues. Bee honey containing such residues poses numerous risks to human health. The aim of the study was to evaluate the effects
Ionela Daniela Morariu +5 more
doaj +1 more source
Journal of Clinical Oncology, 2010 PURPOSE Programmed death-1 (PD-1), an inhibitory receptor expressed on activated T cells, may suppress antitumor immunity. This phase I study sought to determine the safety and tolerability of anti-PD-1 blockade in patients with treatment-refractory ...
J. Brahmer +19 more
semanticscholar +1 more source
Topology and adenocarcinoma cell localization dataset on the labyrinthin diapeutic biomarker
BMC Research Notes, 2023 Objective The discovery and characterization of tumor associated antigens is increasingly important to advance the field of immuno-oncology. In this regard, labyrinthin has been implicated as a neoantigen found on the cell surface of adenocarcinomas ...
Ankit Sharma +3 more
doaj +1 more source
The Immunologic Role of IL-17 in Psoriasis and Psoriatic Arthritis Pathogenesis
Clinical reviews in allergy and immunology, 2018 Psoriasis is a chronic, immune-mediated, inflammatory disease that is pathogenically driven by proinflammatory cytokines. This article reviews the immunologic role of interleukin (IL)-17, the major effector cytokine in the pathogenesis of psoriatic ...
A. Blauvelt, A. Chiricozzi
semanticscholar +1 more source
The Biological Influence and Clinical Relevance of Polymorphism Within the NKG2D Ligands
Frontiers in Immunology, 2018 NKG2D is a major regulator of the activity of cytotoxic cells and interacts with eight different ligands (NKG2DL) from two families of MIC and ULBP proteins.
Jianmin Zuo, Fiyaz Mohammed, Paul Moss
doaj +1 more source
Modeling of endothelial cell dysfunction using human induced pluripotent stem cells derived from patients with end-stage renal disease [PDF]
Kidney Research and Clinical Practice, 2021 Background Endothelial cell (EC) dysfunction is a frequent feature in patients with end-stage renal disease (ESRD). The aim of this study was to generate human induced pluripotent stem cells, differentiate ECs (hiPSC-ECs) from patients with ESRD, and ...
Kyoung Woon Kim +7 more
doaj +1 more source
Journal of Experimental Medicine, 2000 This report shows that cytotoxic T lymphocyte–associated antigen 4 (CTLA-4) plays a key role in T cell–mediated dominant immunologic self-tolerance.
Takeshi Takahashi +7 more
semanticscholar +1 more source