Results 21 to 30 of about 820,874 (269)
The Immunologic Role of IL-17 in Psoriasis and Psoriatic Arthritis Pathogenesis
Clinical reviews in allergy and immunology, 2018 Psoriasis is a chronic, immune-mediated, inflammatory disease that is pathogenically driven by proinflammatory cytokines. This article reviews the immunologic role of interleukin (IL)-17, the major effector cytokine in the pathogenesis of psoriatic ...
A. Blauvelt, A. Chiricozzi
semanticscholar +1 more source
Journal of Orofacial Sciences, 2019 Introduction: Although physical and mechanical properties are extremely important for the effectiveness of prosthetic treatment, materials used for facial rehabilitation should be biocompatible, as the maxillofacial prosthesis is in close contact with ...
Marcelo Coelho Goiato +4 more
doaj +1 more source
Time to First-Line ART Failure and Time to Second-Line ART Switch in the IeDEA Pediatric Cohort [PDF]
, 2018 BACKGROUND: Globally, 49% of the estimated 1.8 million children living with HIV are accessing antiretroviral therapy (ART). There are limited data concerning long-term durability of first-line ART regimens and time to transition to second-line ...
Ayaya, Samuel +16 more
core +2 more sources
Journal of Experimental Medicine, 2000 This report shows that cytotoxic T lymphocyte–associated antigen 4 (CTLA-4) plays a key role in T cell–mediated dominant immunologic self-tolerance.
Takeshi Takahashi +7 more
semanticscholar +1 more source
Sensing Danger: Innate Immunology for Intrusion Detection [PDF]
Information Security Technical Report, 12(4), pp 218-227, 2007, 2008 The immune system provides an ideal metaphor for anomaly detection in general and computer security in particular. Based on this idea, artificial immune systems have been used for a number of years for intrusion detection, unfortunately so far with little success. However, these previous systems were largely based on immunological theory from the 1970s
arxiv +1 more source
Citotoxicidad del glifosato en células mononucleares de sangre periférica humana
Biomédica: revista del Instituto Nacional de Salud, 2007 Introducción. El glifosato es un herbicida de amplio espectro, no selectivo, utilizado comúnmente en agricultura para eliminar malezas. Los estudios que han evaluado la toxicidad del glifosato en animales y en ambiente muestran que las formulaciones ...
Adriano Martínez +2 more
doaj +1 more source
Immunologic and Non-Immunologic Mechanisms Leading to Airway Remodeling in Asthma
International Journal of Molecular Sciences, 2020 Asthma increases worldwide without any definite reason and patient numbers double every 10 years. Drugs used for asthma therapy relax the muscles and reduce inflammation, but none of them inhibited airway wall remodeling in clinical studies.
L. Fang, Q. Sun, M. Roth
semanticscholar +1 more source
The intersection of COVID-19 and autoimmunity: What is our current understanding?
Pathogens and Immunity, 2021 Viral infections have historically had a complex relationship with autoimmune diseases. For patients with preexisting autoimmune disorders, often complicated by immunosuppressive therapies, there are numerous potential effects of COVID-19, a disease of ...
Nicole Eve Winchester +2 more
doaj +1 more source
Long-term calorie restriction in humans is not associated with indices of delayed immunologic aging: A descriptive study. [PDF]
, 2017 BACKGROUND: Delayed immunologic aging is purported to be a major mechanism through which calorie restriction (CR) exerts its anti-aging effects in non-human species.
Epel, Elissa S +8 more
core +3 more sources
ClinicoEconomics and Outcomes Research, 2023 Richard F Pollock,1 Andreas K Slættanes,2 Henrik Brandi,2 Tobias Sydendal Grand2 1Covalence Research Ltd, Harpenden, UK; 2ALK-Abelló A/S, Hørsholm, DenmarkCorrespondence: Andreas K Slættanes, ALK-Abelló A/S, Bøge Allé 1, Hørsholm, DK-2970, Denmark, Tel ...
Pollock RF +3 more
doaj