Results 11 to 20 of about 9,586,847 (376)
Clinical and Applied Thrombosis/Hemostasis, 2022 Background Thrombotic antiphospholipid syndrome (APS) is a systemic autoimmune disease; its diagnosis requires meeting both clinical and laboratory criteria.
Zhenzhen Su MM +7 more
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Function of Protein S-Palmitoylation in Immunity and Immune-Related Diseases
Frontiers in Immunology, 2021 Protein S-palmitoylation is a covalent and reversible lipid modification that specifically targets cysteine residues within many eukaryotic proteins. In mammalian cells, the ubiquitous palmitoyltransferases (PATs) and serine hydrolases, including acyl ...
Yuqi Zhang +4 more
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Complement Activation in Patients With Probable Systemic Lupus Erythematosus and Ability to Predict Progression to American College of Rheumatology-Classified Systemic Lupus Erythematosus. [PDF]
, 2020 ObjectiveTo evaluate the frequency of cell-bound complement activation products (CB-CAPs) as a marker of complement activation in patients with suspected systemic lupus erythematosus (SLE) and the usefulness of this biomarker as a predictor of the ...
Alexander, Roberta Vezza +12 more
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Chinese Expert Consensus on Juvenile Idiopathic Arthritis-associated Uveitis (2023)
Xiehe Yixue Zazhi, 2023 Juvenile idiopathic arthritis (JIA) is a common chronic rheumatologic disease in childhood. JIA-associated uveitis (JIA-U), an important extra-articular complication of JIA, is one of the major causes of childhood disability and blindness.
The Subspecialty Group of Immunology, the Society of Pediatrics, Chinese Medical Association +2 more
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Arthritis Research & Therapy, 2020 Backgrounds Despite the advances of rheumatoid arthritis (RA) therapeutics, several patients do not receive adequate treatment due to the toxicity and/or insufficient response of drugs.
You-Jung Ha +9 more
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Acta Dermato-Venereologica, 2023 Hypopigmented mycosis fungoides is a rare form of mycosis fungoides that is characterized by achromic lesions, early onset of disease, a predilection for darker skinned populations, and a predominance of CD8+ T cells.
Zhong-Hui Hu +7 more
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Co-expression network analysis reveals the pivotal role of mitochondrial dysfunction and interferon signature in juvenile dermatomyositis [PDF]
PeerJ, 2020 Background Juvenile dermatomyositis (JDM) is an immune-mediated disease characterized by chronic organ inflammation. The pathogenic mechanisms remain ill-defined.
Danli Zhong +5 more
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SGK1 Governs the Reciprocal Development of Th17 and Regulatory T Cells
Cell Reports, 2018 A balance between Th17 and regulatory T (Treg) cells is critical for immune homeostasis and tolerance. Our previous work has shown Serum- and glucocorticoid-induced kinase 1 (SGK1) is critical for the development and function of Th17 cells. Here, we show
Chuan Wu +6 more
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Arthritis Research & Therapy, 2022 Objective Neutrophils and aberrant NETosis have been implicated in the pathogenesis of diverse autoimmune diseases; however, their roles in primary Sjögren’s syndrome (pSS) remain unclear.
Yu Peng +17 more
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The immunology of coeliac disease
Springer Seminars in Immunopathology, 1990 Whether or not the immune system initiates CD, it can be seen to play a role in the natural history of the disease. Genetic susceptibility to CD has been shown to be linked to the HLA, DQw2 and it appears that other genes within the MHC further contribute to disease susceptibility. The search for other immune response genes that may be linked to CD has
Mantzaris, G, Rosenberg, WM, Jewell, D
openaire +4 more sources