Results 21 to 30 of about 31,523 (247)

Signature genes associated with immunological non-responsiveness to anti-retroviral therapy in HIV-1 subtype-c infection.

open access: yesPLoS ONE, 2020
ObjectiveHIV-infected individuals undergoing therapy may show an immunological-discordant response to therapy, with poor CD4+ T cells recovery, despite viral suppression below the detection limit.
Sukhvinder Singh   +3 more
doaj   +1 more source

Responding to and Driving Change in Rheumatology: Report from the 12th International Immunology Summit 2021

open access: yesRheumatology and Therapy, 2022
The coronavirus disease 2019 (COVID-19) pandemic has accelerated changes to rheumatology daily clinical practice. The main goal of the 12th International Immunology Summit, held 25-26 June, 2021 (virtual meeting), was to provide direction for these active changes rather than undergoing change reactively in order to improve patient outcomes. This review
Felten, Renaud, Rosine, Nicolas
openaire   +2 more sources

Identification of Potential Diagnostic Genes of HIV-Infected Immunological Non-Responders on Bioinformatics Analysis

open access: yesJournal of Inflammation Research, 2023
HIV-infected immunological non-responders (INRs) failed to achieve the normalization of CD4+ T cell counts despite their undetectable viral load. INRs have an increased risk of clinical progressions of Acquired Immunodeficiency Syndrome (AIDS) and non-AIDS events, accompanied by higher mortality rates than immunological responders (IRs).
Ding,Yanhong   +5 more
openaire   +4 more sources

The Immunomodulatory Effects of Artesunate on Immunological Non-responders in Long-term ART-treated People Living with HIV in Selected Provinces in China: A Non-randomized Concurrent Control Trial

open access: yesPharmacological Research - Modern Chinese Medicine, 2022
Objective: To investigate the immunomodulatory effects of artesunate in the immunologic non-responders (INRs) in people living with HIV (PLWH), and suggest new adjuvant strategies for HIV treatment in INRs.
Zhuang Tao   +10 more
doaj   +1 more source

Investigation on Immunological Factors of Non-and Low-responders to Hepatitis B Vaccine

open access: yesJournal of the Japanese Association for Infectious Diseases, 1993
We investigated the immunological factors concerning the backgrounds of non- and low-responders who could not respond well to the hepatitis B (HB) vaccine. We injected 10 micrograms of the recombinant HB vaccine to the medical staffs of our hospital intramuscularly three times, 199 subjects of whom could receive the full course of immunization with the
FUJISE, Kiyotaka   +6 more
openaire   +3 more sources

The predictive role of CD4+ cell count and CD4/CD8 ratio in immune reconstitution outcome among HIV/AIDS patients receiving antiretroviral therapy: an eight-year observation in China

open access: yesBMC Immunology, 2019
Background The immune reconstitution after initiation of highly active antiretroviral therapy (HAART) among HIV-infected individuals substantially affects patients’ prognosis.
Chong-Xi Li   +9 more
doaj   +1 more source

Gut lactate-producing bacteria promote CD4 T cell recovery on Anti-retroviral therapy in HIV-infected patients

open access: yesComputational and Structural Biotechnology Journal, 2021
Anti-retroviral therapy (ART) effectively suppresses viral replication in HIV-infected patients, however CD4 + cell restoration to normal value is not achieved by 15–20% of patients who are called immune non-responders.
Wei Lyu   +15 more
doaj   +1 more source

Two types of poor immunological responder showing distinct responses to long-term HAART [PDF]

open access: yesInternational Journal of Infectious Diseases, 2019
Most previous studies on poor immunological responders (PIRs) have been performed on one cohort at one time-point following highly active antiretroviral therapy (HAART). The aim of this study was to investigate whether there are different subtypes of PIR and whether a certain population might achieve better immune reconstitution following longer HAART ...
Yaxian Kong   +12 more
openaire   +3 more sources

Seroprotection Status of Hepatitis B Vaccine in Children with Type 1 Diabetes Mellitus [PDF]

open access: yesInternational Journal of Medical Arts, 2021
Background:"Type 1 diabetes mellitus [T1DM]" is the most common endocrine disease in the Pediatric population. It has been suggested that T1DM had inadequate immunological response to vaccines, including hepatitis B virus [HBV] vaccine.Aim of the Work:To
Dina Elsharkawy   +3 more
doaj   +1 more source

Enhanced Gut-Homing Dynamics and Pronounced Exhaustion of Mucosal and Blood CD4+ T Cells in HIV-Infected Immunological Non-Responders

open access: yesFrontiers in Immunology, 2021
Immunological non-responders (INR), a subgroup of people living with HIV (PLHIV) who fail to restore CD4+ T cell numbers upon effective antiretroviral treatment, have impaired gut mucosal barrier function and an inferior clinical prognosis compared with ...
Kristina Berg Lorvik   +19 more
doaj   +1 more source

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