Results 261 to 270 of about 52,207 (332)

Multiple actin networks coordinate mechanotransduction at the immunological synapse. [PDF]

J Cell Biol, 2020
Blumenthal D, Burkhardt JK.
europepmc   +1 more source

Innovative Nanomaterial‐Based Approaches for the Recognition of Amphetamine in Attention Deficit Hyperactivity Disorder Management

Analytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT The rising incidence of amphetamine misuse, particularly in the context of attention deficit hyperactivity disorder treatment, underscores the urgent need for sensitive and effective detection methods. This review examines innovative nanomaterial‐based approaches for AMP detection, emphasizing their advantages over conventional analytical ...
Ilghar Zeinaly, Ghazal Koohkansaadi, Majid Hassanzadeh‐Khanmiri, Ahmad Mobed, Saeid Charsouei, Arash Mohagheghi   +5 more
wiley   +1 more source

Spatiotemporal Regulation of Signaling: Focus on T Cell Activation and the Immunological Synapse. [PDF]

Int J Mol Sci, 2020
Garcia E, Ismail S.
europepmc   +1 more source

Alcohol use and APOE ε4 interaction with cognitive domains among American adults from diverse racial/ethnic groups: A HABS‐HD study

Alzheimer's &Dementia: Behavior &Socioeconomics of Aging, Volume 2, Issue 2, June 2026.
Abstract Introduction We investigated the interaction between alcohol use behavior and apolipoprotein E (APOE) ε4 on cognitive domains among non‐Hispanic Black (NHB), Hispanic, and non‐Hispanic White (NHW) individuals. Methods Using the Health and Aging Brain Study–Health Disparities data, we analyzed 2143 adults aged 50+ using linear regression ...
Edna P. Mendoza‐Villena, Malinee Neelamegam, Nicole Phillips, Leigh Johnson, Lubnaa Abdullah, James Hall, Sid O'Bryant, Eun‐Young Mun, Shea J. Andrews, Robert Barber, Gita A. Pathak, Mohammad Housini, Kai Zhang, Zhengyang Zhou   +13 more
wiley   +1 more source

Checkpoint Genes at the Cancer Side of the Immunological Synapse in Bladder Cancer. [PDF]

Transl Oncol, 2020
Dobosz P, Stempor PA, Roszik J, Herman A, Layani A, Berger R, Avni D, Sidi Y, Leibowitz-Amit R.   +8 more
europepmc   +1 more source

T cell receptor (TCR) clustering in the immunological synapse integrates TCR and costimulatory signaling in selected T cells

, 2005
Bozidar Purtic, Lisa A. Pitcher, Nicolai S. C. van Oers, Christoph Wülfing   +3 more
openalex   +2 more sources

Physiology, pathology and therapeutic potential of microglial triggering receptor expressed on myeloid cells 2 signalling: A narrative update

Clinical and Translational Discovery, Volume 6, Issue 3, June 2026.
TREM2hi microglia and macrophages exert distinct roles in neurological diseases. Enhancing TREM2 signalling supports pathological protein or debris clearance and mitigates inflammation in Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, demyelination disorders and stroke, whereas blocking TREM2 may alleviate tauopathy and ...
Zhe Kong, Libin Shen, Daqing Ma, Jinchao Hou   +3 more
wiley   +1 more source

Glia Are Bussin’: How Single‐Cell and Spatial Transcriptomics Enlighten the Role of Neuroglia in Spinal Cord Injury and Regeneration

Glia, Volume 74, Issue 6, June 2026.
Neuroglia have been extensively profiled using single‐cell genomics, improving our understanding of their dynamics after spinal cord injury. A meta‐analysis of five single‐cell time‐course genomic studies reveals heterogeneity underscoring important challenges for interpretation.
Julio Mejia, Philip J. Horner
wiley   +1 more source

Resilient Biophysical Phenotype of Memory CD4 + T Cells in Long‐Lived Mice

Immunology, Volume 178, Issue 2, Page 363-374, June 2026.
Aging is associated with increased stiffness and reduced migratory capacity of memory CD4+ T cells; however, these biophysical declines do not persist in exceptionally long‐lived mice. Instead, long‐lived individuals preserve T cell mechanics, migration and intracellular architecture, supporting mechanical resilience as a hallmark of successful immune ...
Aldo Abarca‐Ortega, Blanca González‐Bermúdez, Judith Félix‐Escalera, Mónica González‐Sánchez, Enzo Brito, Mónica De la Fuente, Gustavo R. Plaza   +6 more
wiley   +1 more source

Unraveling the Dynamics of Oxytocin in Hypothalamic Neurons

Traffic, Volume 27, Issue 2, June 2026.
Oxytocin (OT) plays an important role in regulating social behavior, and dysregulation of the oxytocinergic system leads to social impairments, such as autism spectrum disorder. Central OT release is poorly understood. Using live‐cell imaging to track vesicle trajectories, combined with machine learning‐based classification, the analysis reveals ...
Beatriz Aznar‐Escolano, Vera Egorova, José Villanueva, Luis Miguel Gutiérrez, Virginia González‐Vélez, Amparo Gil, Sandra Jurado   +6 more
wiley   +1 more source