Results 241 to 250 of about 226,715 (279)
The Journal of Physiology, EarlyView.Abstract figure legend Temporal scaling physiology differs significantly between mice and humans. Mice have higher metabolism, heart and respiratory rate, as well as faster blood flow rates, brain activity and physiological dynamics over time. These differences influence the temporal resolution needed in preclinical imaging of mouse models to ...
Sara Gargiulo, Matteo Gramanzini
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Hypoxia‐induced vulnerability of the somatosensory nervous system
The Journal of Physiology, EarlyView.Abstract figure legend Sensory neurons are highly energy dependent and rely on sufficient oxygen availability to maintain metabolic stability and effective neurocommunication. Within the somatosensory system, even modest reductions in tissue oxygen tension impair neuronal respiration, forcing a shift toward less efficient metabolic pathways that ...
Jack Corbett, Richard P. Hulse
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The Journal of Physiology, EarlyView.Abstract figure legend Atrial fibrillation commonly develops in the left atrium and pulmonary veins (PVs), and can be triggered by sympathetic nerve activity. Here, we examined regional atrial differences in sympathetic nerve distribution and function in the rat.
James Saleeb‐Mousa +6 more
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CO2 chemoreflex contributions to ventilatory long‐term facilitation
The Journal of Physiology, EarlyView.Abstract figure legend To determine whether changes in CO2 chemoreflex sensitivity contribute to ventilatory long‐term facilitation (LTF), we tested the hypothesis that hypercapnic acute intermittent hypoxia (AIH) induces ventilatory LTF and enhances peripheral, but not central, chemoreceptor CO2 chemoreflex sensitivity.
Susan V. Cross +5 more
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Glia, Volume 74, Issue 11, November 2026.Relapsing colitis region‐specific microglial states beyond remission. Cortical microglia remain pro‐inflammatory and synapse‐disruptive, while hippocampal microglia shift toward a reparative program that maintains neuronal circuit stability. ABSTRACT Ulcerative colitis (UC) patients experience cycles of active gut inflammation and remission, with ...
Lorena Morton +6 more
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The importance of cross‐talk in research and the body: An early career researcher perspective
Experimental Physiology, EarlyView.
Lucy J. Ryan +3 more
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Immunology. The immunological synapse--a multitasking system.
Science (New York, N.Y.), 2002 Van Der Merwe, P, Davis, S
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Annual Review of Immunology, 2001 The adaptive immune response is initiated by the interaction of T cell antigen receptors with major histocompatibility complex molecule-peptide complexes in the nanometer scale gap between a T cell and an antigen-presenting cell, referred to as an ...
Andrey Shaw, Mark Davis, Paul Allen
exaly +5 more sources
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A check on the immunological synapse
Science Signaling, 2023Blocking Nogo receptor 1 on natural killer cells enhances cell killing by stabilizing contact with target cells.
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Communication, the centrosome and the immunological synapse [PDF]
Philosophical Transactions of the Royal Society B: Biological Sciences, 2014 Recent findings on the behaviour of the centrosome at the immunological synapse suggest a critical role for centrosome polarization in controlling the communication between immune cells required to generate an effective immune response. The features observed at the immunological synapse show parallels to centrosome (basal body) polarization seen in ...
Gillian Griffiths, Jane Stinchcombe
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