Results 221 to 230 of about 52,207 (332)
Beyond the chaos: How architecture structures tumour biology
Tissue architecture shapes tumour initiation and progression through multiple interconnected layers continuously remodelled over time. This review outlines how physical forces, biochemical cues, cellular niches and systemic influences contribute to tumour evolution.
Lea Dörner +3 more
wiley +1 more source
Role of Actin Cytoskeleton Reorganization in Polarized Secretory Traffic at the Immunological Synapse. [PDF]
Calvo V, Izquierdo M.
europepmc +1 more source
Cx43-Gap Junctions Accumulate at the Cytotoxic Immunological Synapse Enabling Cytotoxic T Lymphocyte Melanoma Cell Killing [PDF]
Francisca Hofmann +6 more
openalex +1 more source
Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin +2 more
wiley +1 more source
Emerging mechanisms of ILC2‐neuronal crosstalk across the body
Emerging roles of ILC2 in neuronal crosstalk across organs. In a series of studies published in 2025, ILC2 were shown to regulate nervous system function across a range of organs across the body. Within the intestinal tract, ILC2‐derived cytokines acted on enteric neurons to orchestrate immunity to helminths (Wang et al).
David A Posner, Matthew R Hepworth
wiley +1 more source
Developing T cells form an immunological synapse for passage through the β-selection checkpoint. [PDF]
Allam AH +3 more
europepmc +1 more source
Dendritic cell actin dynamics control contact duration and priming efficiency at the immunological synapse. [PDF]
Leithner A +8 more
europepmc +1 more source
The role of DISC1 in the organization of the T-cell immunological synapse
Nicholas A. Maskalenko +1 more
openalex +1 more source

