ABSTRACT Sheep production contributes to a secure and diverse food and fibre supply in the United States, with growing ethnic diversity strengthening demand. Katahdin is a composite hair‐type sheep breed developed in the United States that has become the most popular breed in many regions of the country and the first one to have genomic selection ...
Alejandra Toro Ospina +6 more
wiley +1 more source
Is the tumor cell side of the immunological synapse a polarized secretory domain? [PDF]
Biolato AM +6 more
europepmc +1 more source
Three-Dimensional Single Molecule Localization Microscopy Reveals the Topography of the Immunological Synapse at Isotropic Precision below 15 nm. [PDF]
Velas L +7 more
europepmc +1 more source
Quantitative Imaging Approaches to Study the CAR Immunological Synapse [PDF]
Malini Mukherjee +4 more
openalex +1 more source
Gestational kynurenine metabolites mediate effects of pregnancy adiposity on child negative affect
Background Mounting evidence links increased adiposity during pregnancy and offspring risk for mental health disorders. Yet the mechanisms underlying this association remain poorly understood, limiting our ability to design effective interventions.
Hanna C. Gustafsson +4 more
wiley +1 more source
Immunological synapse formation as a key mechanism in T cell-dependent bispecific antibody-mediated immune activation and cytotoxicity. [PDF]
Nakamura R +4 more
europepmc +1 more source
LFA-1 and CD2 Synergize for the Erk1/2 Activation in the Natural Killer (NK) Cell Immunological Synapse [PDF]
Xiaodong Zheng +4 more
openalex +1 more source
Genomic and proteomic insights into hidradenitis suppurativa
A dual pathogenic model of HS involving both epithelial dysfunction and systemic inflammation is supported. The HLA‐DRA association hints at autoimmune overlap, but the proteomic signature which is dominated by innate immune mediators favours an autoinflammatory classification, which may guide future therapeutic strategies and patient stratification ...
Maria Argyropoulou +8 more
wiley +1 more source
CD2 augmentation enhances CAR-T-cell efficacy via immunological synapse remodeling and T-cell exhaustion mitigation. [PDF]
Zhu Q +8 more
europepmc +1 more source

