Results 1 to 10 of about 1,284,834 (277)
Frontiers in Immunology, 2022 Upon interaction with immobilized antigens, B cells form an immune synapse where actin remodeling and re-positioning of the microtubule-organizing center (MTOC) together with lysosomes can facilitate antigen extraction.
Romina Ulloa +12 more
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Complement controls the immune synapse and tumors control complement
Journal for ImmunoTherapy of Cancer, 2020 The synapses between immune cells and their targets are 150 Å wide. They regulate immune cell responses (IRs) to cognate antigens. Here, I outline a potential mechanism for self-nonself discrimination based on the C3d and iC3b proteolytic fragments of ...
Alan Herbert
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Frontiers in Cell and Developmental Biology, 2021 T cell receptor (TCR) and B cell receptor (BCR) stimulation by antigen presented on an antigen-presenting cell (APC) induces the formation of the immune synapse (IS), the convergence of secretory vesicles from T and B lymphocytes toward the centrosome ...
Victor Calvo, Manuel Izquierdo
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Frontiers in Immunology, 2023 Cytotoxic lymphocytes (CLs), specifically cytotoxic T lymphocytes and natural killer cells, are indispensable guardians of the immune system and orchestrate the recognition and elimination of cancer cells. Upon encountering a cancer cell, CLs establish a
Elena Ockfen +6 more
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A Novel Peptide-MHC Targeted Chimeric Antigen Receptor T Cell Forms a T Cell-like Immune Synapse
Biomedicines, 2021 Chimeric Antigen Receptor (CAR) T cell therapy is a promising form of adoptive cell therapy that re-engineers patient-derived T cells to express a hybrid receptor specific to a tumour-specific antigen of choice.
Stacie Shiqi Wang +6 more
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B Cell Mechanosensing Regulates ER Remodeling at the Immune Synapse [PDF]
Frontiers in ImmunologyMaría-Isabel Yuseff
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Correction to: Cinnamon extract induces tumor cell death through inhibition of NFκB and AP1
BMC Cancer, 2019 Following publication of the original article [1], the authors have re-evaluated the authorship for this article. The updated author group is:
Ho-Keun Kwon +10 more
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In vitro Assessment of Immunological Synapse Formation by Flow Cytometry
Bio-Protocol, 2016 In adaptive immune system, formation of immunological synapse between T cells and antigen presenting cells (dendritic cells, B cells, and macrophages) or target cells (tumor cells and viral-infected cells) is critical for the execution of T cell immune ...
Bo-Ra Na, Chang-Duk Jun
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Frontiers in Immunology, 2022 Hemichannels (HCs)/gap junctions (GJs) and immunoglobulin (Ig)-like domain-containing proteins (IGLDCPs) are involved in the innate–adaptive immune response independently.
Jiang-Hui Meng +8 more
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T Cell Microvilli: Sensors or Senders?
Frontiers in Immunology, 2019 Communication between cells is essential for multicellular life. During cognate immune interactions, T cells communicate with antigen-presenting cells (APC) via direct cell–cell contact or the release of molecules and vesicles containing T cell messages.
Hye-Ran Kim +3 more
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