Results 31 to 40 of about 76,481 (272)
Immunological synapse: An emerging target for immune regulation [PDF]
, 2023 Immunological synapse is termed as a steady interface between immune cells (mainly T-lymphocyte) i.e., derived from thymus along with adhesion molecules and antigen presenting cell (APC).
Nabaneeta Smaraki*1 , Harsh Rajeshbhai Jogi1 , Sonali Sonejita Nayak2, , Ashok Chaudhary2
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Frontiers in Cell and Developmental Biology, 2021 T cell receptor (TCR) and B cell receptor (BCR) stimulation by antigen presented on an antigen-presenting cell (APC) induces the formation of the immune synapse (IS), the convergence of secretory vesicles from T and B lymphocytes toward the centrosome ...
Victor Calvo, Manuel Izquierdo
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Imaging the immune synapse: three-dimensional analysis of the immune synapse
, 2023 ABSTRACT T cell receptor (TCR) stimulation of T lymphocytes by antigen bound to the major histocompatibility complex (MHC) of an antigen-presenting cell (APC), together with the interaction of accessory molecules, induces the formation of the immunological synapse (IS), the convergence of secretion vesicles towards the centrosome, and ...
Javier Ruiz-Navarro +3 more
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Frontiers in Immunology, 2023 Cytotoxic lymphocytes (CLs), specifically cytotoxic T lymphocytes and natural killer cells, are indispensable guardians of the immune system and orchestrate the recognition and elimination of cancer cells. Upon encountering a cancer cell, CLs establish a
Elena Ockfen +6 more
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A Novel Peptide-MHC Targeted Chimeric Antigen Receptor T Cell Forms a T Cell-like Immune Synapse
Biomedicines, 2021 Chimeric Antigen Receptor (CAR) T cell therapy is a promising form of adoptive cell therapy that re-engineers patient-derived T cells to express a hybrid receptor specific to a tumour-specific antigen of choice.
Stacie Shiqi Wang +6 more
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Correction to: Cinnamon extract induces tumor cell death through inhibition of NFκB and AP1
BMC Cancer, 2019 Following publication of the original article [1], the authors have re-evaluated the authorship for this article. The updated author group is:
Ho-Keun Kwon +10 more
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In vitro Assessment of Immunological Synapse Formation by Flow Cytometry
Bio-Protocol, 2016 In adaptive immune system, formation of immunological synapse between T cells and antigen presenting cells (dendritic cells, B cells, and macrophages) or target cells (tumor cells and viral-infected cells) is critical for the execution of T cell immune ...
Bo-Ra Na, Chang-Duk Jun
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F-actin-binding protein drebrin regulates CXCR4 recruitment to the immune synapse [PDF]
, 2010 Acknowledgements This work was partly supported by EU-México FONCICYT –C002-2008-1 ALA/127249, SAF-2008-02635, INSINET 01592006 CAM, Red RECAVA RD06/0014-0030 and FIPSE 36658/07 grants. E.V.C.
Gordón-Alonso, Mónica +14 more
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Differential segregation in a cell-cell contact interface: the dynamics of the immunological synapse [PDF]
, 2002 Receptor-ligand couples in the cell-cell contact interface between a T cell and an antigen-presenting cell form distinct geometric patterns and undergo spatial rearrangement within the contact interface.
Nigel John Burroughs +3 more
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T Cell Microvilli: Sensors or Senders?
Frontiers in Immunology, 2019 Communication between cells is essential for multicellular life. During cognate immune interactions, T cells communicate with antigen-presenting cells (APC) via direct cell–cell contact or the release of molecules and vesicles containing T cell messages.
Hye-Ran Kim +3 more
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