Results 31 to 40 of about 1,158,960 (278)

A Novel Peptide-MHC Targeted Chimeric Antigen Receptor T Cell Forms a T Cell-like Immune Synapse

Biomedicines, 2021
Chimeric Antigen Receptor (CAR) T cell therapy is a promising form of adoptive cell therapy that re-engineers patient-derived T cells to express a hybrid receptor specific to a tumour-specific antigen of choice.
Stacie Shiqi Wang, Kylie Luong, Fiona Margaret Gracey, Shereen Jabar, Brad McColl, Ryan Stanley Cross, Misty Rayna Jenkins   +6 more
doaj   +1 more source

Correction to: Cinnamon extract induces tumor cell death through inhibition of NFκB and AP1

BMC Cancer, 2019
Following publication of the original article [1], the authors have re-evaluated the authorship for this article. The updated author group is:
Ho-Keun Kwon, Ji-Sun Hwang, Jae-Seon So, Choong-Gu Lee, Anupama Sahoo, Jae-Ha Ryu, Won Kyung Jeon, Byoung Seob Ko, Sung Haeng Lee, Zee Yong Park, Sin-Hyeog Im   +10 more
doaj   +1 more source

In vitro Assessment of Immunological Synapse Formation by Flow Cytometry

Bio-Protocol, 2016
In adaptive immune system, formation of immunological synapse between T cells and antigen presenting cells (dendritic cells, B cells, and macrophages) or target cells (tumor cells and viral-infected cells) is critical for the execution of T cell immune ...
Bo-Ra Na, Chang-Duk Jun
doaj   +1 more source

Differential segregation in a cell-cell contact interface: the dynamics of the immunological synapse [PDF]

, 2002
Receptor-ligand couples in the cell-cell contact interface between a T cell and an antigen-presenting cell form distinct geometric patterns and undergo spatial rearrangement within the contact interface.
Nigel John Burroughs, Burroughs, Nigel John, Wülfing, Christoph, Christoph Wülfing   +3 more
core   +1 more source

Boltzmann energy-based image analysis demonstrates that extracellular domain size differences explain protein segregation at immune synapses [PDF]

, 2011
Immune synapses formed by T and NK cells both show segregation of the integrin ICAM1 from other proteins such as CD2 (T cell) or KIR (NK cell).
Dustin, Michael L., van der Merwe P. Anton, Nigel J Burroughs, Michael L Dustin, Van Der Merwe, PA, P Anton van der Merwe, Nigel J. Burroughs, Miloserdov, Vladimir, Van der Merwe, P. Anton, Miloserdov, V, Davis, DM, Dustin, ML, Daniel M Davis, Daniel M. Davis, Davis Daniel M., Köhler, K, Michael L. Dustin, Miloserdov Vladimir, Karsten Köhler, Dustin, Michael, Burroughs Nigel J., Dustin Michael L., Burroughs, Nigel J., P. Anton van der Merwe, Davis, Daniel M., Burroughs, NJ, Köhler Karsten, Van Der Merwe, Philip, Köhler, Karsten, Burroughs, Nigel John, Vladimir Miloserdov   +30 more
core   +1 more source

menchelab/hci-immune-synapse: v2

, 2021
Revised ...
Vulliard Loan
core   +1 more source

T Cell Microvilli: Sensors or Senders?

Frontiers in Immunology, 2019
Communication between cells is essential for multicellular life. During cognate immune interactions, T cells communicate with antigen-presenting cells (APC) via direct cell–cell contact or the release of molecules and vesicles containing T cell messages.
Hye-Ran Kim, Hye-Ran Kim, Chang-Duk Jun, Chang-Duk Jun   +3 more
doaj   +1 more source

Cross-Activation of Hemichannels/Gap Junctions and Immunoglobulin-Like Domains in Innate–Adaptive Immune Responses

Frontiers in Immunology, 2022
Hemichannels (HCs)/gap junctions (GJs) and immunoglobulin (Ig)-like domain-containing proteins (IGLDCPs) are involved in the innate–adaptive immune response independently.
Jiang-Hui Meng, Jiang-Hui Meng, Chang-Xu Chen, Chang-Xu Chen, Mohammad R. Ahmadian, Hong Zan, Kai-Jun Luo, Kai-Jun Luo, Jean X. Jiang   +8 more
doaj   +1 more source

Systems Imaging of the Immune Synapse [PDF]

, 2017
Three-dimensional live cell imaging of the interaction of T cells with antigen-presenting cells (APCs) visualizes the subcellular distributions of signaling intermediates during T cell activation at thousands of resolved positions within a cell. These information-rich maps of local protein concentrations are a valuable resource in understanding T cell ...
Wuelfing, Christoph, Ambler, Rachel, RUAN, Xiangtao, Murphy, Robert F.   +3 more
openaire   +3 more sources

Immune synapses: mitochondrial morphology matters [PDF]

The EMBO Journal, 2011
Proper positioning of mitochondria is critical for cellular function. Mitochondria localization close to synapses regulates signalling at neuronal and immune synapses (ISs). Vice versa, synapses influence activity, motility and the fusion/fission balance of close‐by mitochondria.
Christian, Junker, Markus, Hoth
openaire   +2 more sources