Results 21 to 30 of about 73,161 (247)
Correction to: Cinnamon extract induces tumor cell death through inhibition of NFκB and AP1
BMC Cancer, 2019 Following publication of the original article [1], the authors have re-evaluated the authorship for this article. The updated author group is:
Ho-Keun Kwon +10 more
doaj +1 more source
In vitro Assessment of Immunological Synapse Formation by Flow Cytometry
Bio-Protocol, 2016 In adaptive immune system, formation of immunological synapse between T cells and antigen presenting cells (dendritic cells, B cells, and macrophages) or target cells (tumor cells and viral-infected cells) is critical for the execution of T cell immune ...
Bo-Ra Na, Chang-Duk Jun
doaj +1 more source
Frontiers in Immunology, 2022 Hemichannels (HCs)/gap junctions (GJs) and immunoglobulin (Ig)-like domain-containing proteins (IGLDCPs) are involved in the innate–adaptive immune response independently.
Jiang-Hui Meng +8 more
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T Cell Microvilli: Sensors or Senders?
Frontiers in Immunology, 2019 Communication between cells is essential for multicellular life. During cognate immune interactions, T cells communicate with antigen-presenting cells (APC) via direct cell–cell contact or the release of molecules and vesicles containing T cell messages.
Hye-Ran Kim +3 more
doaj +1 more source
Immune synapses: mitochondrial morphology matters [PDF]
The EMBO Journal, 2011 Proper positioning of mitochondria is critical for cellular function. Mitochondria localization close to synapses regulates signalling at neuronal and immune synapses (ISs). Vice versa, synapses influence activity, motility and the fusion/fission balance of close‐by mitochondria.
Christian, Junker, Markus, Hoth
openaire +2 more sources
Complement controls the immune synapse and tumors control complement
Journal for ImmunoTherapy of Cancer, 2020 The synapses between immune cells and their targets are 150 Å wide. They regulate immune cell responses (IRs) to cognate antigens. Here, I outline a potential mechanism for self-nonself discrimination based on the C3d and iC3b proteolytic fragments of ...
Alan Herbert
doaj +1 more source
Receptor Signaling Clusters in the Immune Synapse [PDF]
Annual Review of Biophysics, 2012 Signaling processes between various immune cells involve large-scale spatial reorganization of receptors and signaling molecules within the cell-cell junction. These structures, now collectively referred to as immune synapses, interleave physical and mechanical processes with the cascades of chemical reactions that constitute signal transduction ...
Dustin, Michael L, Groves, Jay T
openaire +4 more sources
Systems Imaging of the Immune Synapse [PDF]
, 2017 Three-dimensional live cell imaging of the interaction of T cells with antigen-presenting cells (APCs) visualizes the subcellular distributions of signaling intermediates during T cell activation at thousands of resolved positions within a cell. These information-rich maps of local protein concentrations are a valuable resource in understanding T cell ...
Wuelfing, Christoph +3 more
openaire +3 more sources
Folding for the Immune Synapse: CCT Chaperonin and the Cytoskeleton. [PDF]
Front Cell Dev Biol, 2021 Lymphocytes rearrange their shape, membrane receptors and organelles during cognate contacts with antigen-presenting cells (APCs). Activation of T cells by APCs through pMHC-TCR/CD3 interaction (peptide-major histocompatibility complex-T cell receptor/CD3 complexes) involves different steps that lead to the reorganization of the cytoskeleton and ...
Martín-Cófreces NB +2 more
europepmc +7 more sources
Frontiers in Cellular Neuroscience, 2020 Synapse loss is the strongest correlate for cognitive decline in Alzheimer's disease. The mechanisms underlying synapse loss have been extensively investigated using mouse models expressing genes with human familial Alzheimer's disease mutations. In this
Jaichandar Subramanian +5 more
doaj +1 more source