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Negative allosteric modulation of mGlu7 disrupts fear memory reconsolidation and glutamatergic signaling in rat and human brain tissue. [PDF]

open access: yesMol Psychiatry
Ciobanu AC   +11 more
europepmc   +1 more source
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The immunological synapse

Molecular Immunology, 2002
The immunological synapse plays a central role in organising the immune system. Through their synaptic activity both T and B cells usually, but not always, acquire the information that critically determines the level and nature of the responses that they make. For T cells much of that information comes from epicrine and paracrine cell-cell interactions
R J, Creusot   +2 more
openaire   +2 more sources

Imaging Immunological Synapses

Science's STKE, 2000
Immunological synapses arise at contact zones between antigen-presenting cells and T cells. Synapses have distinct organization and are composed of T cell receptors interacting with major histocompatibility complex-peptide entities surrounded by various potentiating coreceptors and signaling molecules that migrate into the synapse through ...
  +4 more sources

Plasticity of Immunological Synapses

2009
TCR engagement with peptide/MHC complexes displayed on the surface of the antigen-presenting cells is the crucial event in developing an adaptive immune response and occurs within specialized signaling areas named immunological synapses. Immunological synapses are diverse both in structure and function and exhibit a strikingly dynamic molecular ...
Salvatore, Valitutti, Loïc, Dupré
openaire   +2 more sources

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