Results 131 to 140 of about 10,784 (232)

Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang, Bowen Li, Pan Tang, Fanchen Yan, Shuxin Wang, Guiying Leng, Panduo Dawa, Yuansi Chen, Yihan Guo, Pan Yang, Yi Li, Siyu Liu, Erdan Dong, Siyuan Qin, Zhoufeng Wang   +14 more
wiley   +1 more source

Immunometabolism in atherosclerosis:a new understanding of an old disease [PDF]

Atherosclerosis, a chronic inflammatory condition, remains a leading cause of death globally, necessitating innovative approaches to target pro-atherogenic pathways.
Certo, Michelangelo; id_orcid, Mauro, Claudio; id_orcid, Rahimzadeh, Mahsa   +2 more
core   +1 more source

Magnesium as a Bioenergetic Checkpoint Linking Mitochondrial Function, Metabolic Disease, and Aging

Aging Cell, Volume 25, Issue 6, June 2026.
This review positions magnesium as a central bioenergetic checkpoint that orchestrates mitochondrial function and metabolic resilience. By defining the functional ATP pool and stabilizing mitochondrial performance, magnesium homeostasis serves as a mechanistic link between renal handling, metabolic disease, and the aging process.
Chien‐Wei Huang, Chen‐Yueh Wen, Andy P. Tsai, Boyang Wang, Kuan‐Hao Tsui, Yu‐Juei Hsu, Chia‐Jung Li   +6 more
wiley   +1 more source

Immunometabolism of macrophages in the bone microenvironment: a new perspective for bone healing therapy

Journal of Advanced Research
Background: Immunometabolism, the regulation of immune cell function through metabolic pathways, has emerged as a key focus in regenerative medicine.
Chenyu Wang, Qihang Wu, Luyao Zhuang, Yiqi Chen, Qiu Zhang, Yinuo Wu, Mingyang Jin, Jiansen Miao, Xiangyang Wang, Jiake Xu, Haiming Jin   +10 more
doaj   +1 more source

Immune endotypes in tuberculosis: Keys to decoding disease complexity

Journal of Internal Medicine, Volume 299, Issue 6, Page 670-693, June 2026.
Abstract Tuberculosis (TB) remains a major global health challenge, with multi‐drug antibiotic regimens as the current standard of care. While effective at killing Mycobacterium tuberculosis, these treatments do not resolve persistent inflammation, prevent lung damage, or reverse immune dysregulation that contribute to poor outcomes and disease ...
Shamila D. Alipoor, Julia Guthrie, Lina Davies Forsman, Andrew R. Di Nardo, Susanna Brighenti   +4 more
wiley   +1 more source

Steroid hormone regulation of immunometabolism and inflammation [PDF]

The metabolism of immune cells adapts to support the energy demands for their activation, differentiation, and effector functions through a process known as metabolic reprogramming.
Ji-Young Lee, Clinton B. Mathias, Mohankumar Ramar, Ley Cody Smith, Gregory L. Riley   +4 more
core   +1 more source

Unraveling the immunometabolism puzzle: Deciphering systemic sclerosis pathogenesis

The article delves into the pathogenesis of systemic sclerosis (SSc) with an emphasis on immunometabolism dysfunctions. SSc is a complex autoimmune connective tissue disorder with skin and organ fibrosis manifestation, vasculopathy, and immune ...
Maryam Masoumi, Ali Saeedi-Boroujeni, Jafar Karami, Hossein Khorramdelazad, Ali Bayat Bodaghi, Erfan Ebadi, Sheyda Houshmandfar   +6 more
core   +1 more source

Unlocking Single-Cell Immunometabolism Research: A Call for Accessible Tools [PDF]

International audienceRecent technological advances permit the profiling of metabolic changes in single cells, which sheds light on how metabolism regulates immune responses.
Hartmann, F., Opitz, C., Hartmann, Felix J, Argüello, Rafael, Alexandrov, Theodore, Lyssiotis, Costas A., Argüello, R., Corrado, M., Kielian, Tammy, Zanoni, I., Argüello, Rafael J., Marçais, A., Opitz, Christiane A., Bergthaler, A., Martínez-Martín, N., Bergthaler, Andreas, Bousso, Philippe, Cosgrove, J., Bousso, P., Marçais, Antoine, Perié, L., Lyssiotis, Costas, Kielian, T., Martínez-Martín, Nuria, Cabezas-Wallscheid, Nina, van den Bossche, Jan, Zanoni, Ivan, Hartmann, Felix, Corrado, Mauro, Cosgrove, Jason, den Bossche, J., Perié, Leïla, Lyssiotis, C., Opitz, Christiane, Alexandrov, T., Cabezas-Wallscheid, N.   +35 more
core   +1 more source

Immunometabolism in Livestock

Animal Frontiers, 2022
openaire   +2 more sources

Immunometabolism: signaling pathways, homeostasis, and therapeutic targets

Immunometabolism plays a central role in sustaining immune system functionality and preserving physiological homeostasis within the organism. During the differentiation and activation, immune cells undergo metabolic reprogramming mediated by complex ...
Jia Xu, Ganjun Yu, Rongrong Xu, Yanfeng Wu, Xiaobo He   +4 more
core   +1 more source