Results 131 to 140 of about 15,033 (230)

Immunometabolism unveiled: Pioneering breakthroughs in cancer therapeutics

Molecular Oncology
The field of immunometabolism cannot be considered ‘emerging’ anymore; it is at the moment one of the most active and rapidly evolving areas of biomedical research. Its hottest zone is cancer immunometabolism. This is partly due to the clinical application of immunotherapy, with either antibodies (checkpoint blockade) or cellular therapies (e.g., CAR‐T
Eric Eldering, Jean‐Ehrland Ricci
openaire   +4 more sources

The metabolism-immunity axis in Immune thrombocytopenia: from energy regulation to targeted therapy

Pharmacological Research
Immunometabolism has received significant interest as a field exploring the dynamic interation between the immune system and metabolic processes. Immune cell activation, proliferation, and function are tightly regulated by metabolism, and metabolic ...
Xin Zhou, Ning-ning Shan
doaj   +1 more source

Hepatocyte-specific HIF-1α ablation improves obesity-induced glucose intolerance by reducing first-pass GLP-1 degradation. [PDF]

, 2019
The decrease in incretin effects is an important etiologic component of type 2 diabetes with unknown mechanisms. In an attempt to understand obesity-induced changes in liver oxygen homeostasis, we found that liver HIF-1α expression was increased mainly ...
Bandyopadhyay, Guatam K, Cabrales, Pedro, Lee, Yun Sok, Riopel, Matthew   +3 more
core  

The novel mechanism facilitating chronic hepatitis B infection: immunometabolism and epigenetic modification reprogramming

Frontiers in Immunology
Hepatitis B Virus (HBV) infections pose a global public health challenge. Despite extensive research on this disease, the intricate mechanisms underlying persistent HBV infection require further in-depth elucidation.
Zhengmin Wang, Nan Liu, Yang Yang, Zhengkun Tu, Zhengkun Tu   +4 more
doaj   +1 more source

HPV vaccination improves immune response in children with respiratory papillomatosis

Scientific Reports
Recurrent respiratory papillomatosis (RRP) is a pathology characterized by the presence of neoplasm in the epithelium of the airways, where the larynx is the main affected organ. The cause of this disease is the low-risk Human Papillomavirus (HPV), where
Miguel A. Prieto-Islas, Esmeralda Godoy-Dahbura, Diana C. Villalpando-Sánchez, Cristina Cortés-Benavides, Eduardo Hernández-Cuellar, Denisse Castro-Eguiluz, Hiram Alvarez-Neri, Oscar Medina-Contreras   +7 more
doaj   +1 more source

Immunometabolism of macrophages in the bone microenvironment: a new perspective for bone healing therapy

Journal of Advanced Research
Background: Immunometabolism, the regulation of immune cell function through metabolic pathways, has emerged as a key focus in regenerative medicine.
Chenyu Wang, Qihang Wu, Luyao Zhuang, Yiqi Chen, Qiu Zhang, Yinuo Wu, Mingyang Jin, Jiansen Miao, Xiangyang Wang, Jiake Xu, Haiming Jin   +10 more
doaj   +1 more source

PPARγ mediated enhanced lipid biogenesis fuels Mycobacterium tuberculosis growth in a drug-tolerant hepatocyte environment

eLife
Mycobacterium tuberculosis (Mtb) infection of the lungs, besides producing prolonged cough with mucus, also causes progressive fatigue and cachexia with debilitating loss of muscle mass.
Binayak Sarkar, Jyotsna Singh, Mohit Yadav, Priya Sharma, Raman Deep Sharma, Shweta Singh, Aakash Chandramouli, Kritee Mehdiratta, Ashwani Kumar, Siddhesh S Kamat, Devram S Ghorpade, Debasisa Mohanty, Dhiraj Kumar, Rajesh S Gokhale   +13 more
doaj   +1 more source

Role of Tumor Microenvironment in Prostate Cancer Immunometabolism

Biomolecules
The tumor microenvironment (TME) plays a pivotal role in shaping immunometabolism in prostate cancer, influencing disease progression and therapeutic response.
Yutao Wang, Yiming Chen, Jianfeng Wang
doaj   +1 more source

Repurposing metformin for cardiovascular disease [PDF]

, 2018
Lang, Chim C., Rena, Graham
core   +2 more sources

Immunometabolism in Livestock

Animal Frontiers, 2022
openaire   +2 more sources