Results 121 to 130 of about 12,077 (249)
eLifeMycobacterium tuberculosis (Mtb) infection of the lungs, besides producing prolonged cough with mucus, also causes progressive fatigue and cachexia with debilitating loss of muscle mass.
Binayak Sarkar +13 more
doaj +1 more source
Advanced Science, Volume 13, Issue 44, 7 August 2026.This review explains how chronic liver injury progresses toward hepatocellular carcinoma through interconnected changes in gut microbes, metabolism, immunity, fibrosis, and diet. It highlights microbial metabolites, bile‐acid signaling, immune dysfunction, and nutritional or microbiome‐based interventions as opportunities to identify risk earlier ...
Yi Hu +5 more
wiley +1 more source
Advanced Science, Volume 13, Issue 44, 7 August 2026.A sulfated polysaccharide (SCP) from Cyclocarya paliurus alleviates ulcerative colitis by reshaping the gut microbiome. This remodeled microbiota orchestrates the upregulation of the host‐derived lipid 12‐HEPE, which directly inhibits the TLR4/NF‐κB pathway to suppress inflammation.
Xianxiang Chen +11 more
wiley +1 more source
The metabolism-immunity axis in Immune thrombocytopenia: from energy regulation to targeted therapy
Pharmacological ResearchImmunometabolism has received significant interest as a field exploring the dynamic interation between the immune system and metabolic processes. Immune cell activation, proliferation, and function are tightly regulated by metabolism, and metabolic ...
Xin Zhou, Ning-ning Shan
doaj +1 more source
Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.Glucose, galactose, mannose and fructose can either fuel or fight tumours by rewiring metabolism and immunity. Their context‐dependent double‐edged nature suggests that precisely targeted monosaccharide interventions could become a new pillar of precision oncology.
Qin Ouyang, Ke Gao, Haojie Lu, Shu Zhang
wiley +1 more source
Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.1. Indoleamine 2,3‐dioxygenase (IDO) acts as a time‐dependent metabolic–immune switch in the acute kidney injury‐to‐chronic kidney disease transition, protective early but pathogenic when sustained. 2. Early protection (regulatory T cell expansion, M2 polarisation and ferroptosis suppression) gives way to general control nonderepressible 2‐driven ...
Ziyi Qiu, Binbin Pan
wiley +1 more source
Neutrophil‐based immunotherapy: A metabolic lens on mechanisms and therapeutic implications
Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.TAN metabolic reprogramming critically contributes to tumour immune evasion. A 4‑Tier TAN‑MetaC classification framework is proposed, along with an overview of translational opportunities and bottlenecks for TAN metabolism‑targeted immunotherapies. Abstract Background Tumor‐associated neutrophils (TANs) serve as pivotal immune modulators in the tumor ...
Wenchao Xu +4 more
wiley +1 more source
Oxidized Low-Density Lipoprotein and Its Role in Immunometabolism
International Journal of Molecular SciencesModified cholesterols such as oxidized low-density lipoprotein (OxLDL) contribute to atherosclerosis and other disorders through the promotion of foam cell formation and inflammation.
Negin Mosalmanzadeh, Brandt D. Pence
semanticscholar +1 more source
Health Science Reports, Volume 9, Issue 8, August 2026.ABSTRACT Background and Aims The combined prognostic value of metaflammation and vascular aging markers in cardiovascular‐kidney‐metabolic (CKM) syndrome is unclear. This study aimed to assess the independent and joint associations of the C‐reactive protein‐triglyceride glucose index (CTI) and estimated pulse wave velocity (ePWV) with all‐cause ...
Huixiao Yuan +8 more
wiley +1 more source