Results 101 to 110 of about 10,784 (232)

Immunometabolism and Exercise: New avenues

, 2017
Immune system and cell metabolism have been interacted constantly, by synthesis and release of immunomodulatory proteins, recognized as cytokines, in order to maintain the body homeostasis.
De Moura Antunes, Barbara [UNESP], Daniela S Inoue, Inoue, Daniela Sayuri [UNESP], Neto, José Cesar Rosa, Barbara MM Antunes, Fabrício E Rossi, Lir, Fábio Santos [UNESP], Fábio S Lira, José Cesar Rosa Neto, Rossi, Fabrício Eduardo [UNESP]   +9 more
core   +1 more source

Short-Term High- and Moderate-Intensity Training Modifies Inflammatory and Metabolic Factors in Response to Acute Exercise

Frontiers in Physiology, 2017
Purpose: To compare the acute and chronic effects of high intensity intermittent training (HIIT) and steady state training (SST) on the metabolic profile and inflammatory response in physically active men.Methods: Thirty recreationally active men were ...
Fabio Santos Lira, Thaislaine dos Santos, Renan Santos Caldeira, Daniela S. Inoue, Valéria L. G. Panissa, Carolina Cabral-Santos, Eduardo Z. Campos, Bruno Rodrigues, Paula A. Monteiro   +8 more
doaj   +1 more source

The Complex Relation of Branched‐Chain Amino Acids and Inflammation in the Obesity and Diabetes Context

Obesity Reviews, Volume 27, Issue 7, July 2026.
ABSTRACT In a scenario with increasing cases of obesity and diabetes worldwide, branched‐chain amino acids (BCAA) metabolism has become an important factor in the understanding of these pathologies. More recently, its chronic high plasma levels have been postulated, alongside glucose, inflammatory factors, and other molecules, as an important ...
Bernardo Starling‐Soares, Monique Macedo Coelho, Bruna Guerra Campolina, Camila Kümmel Duarte, Tatiani Uceli Maioli   +4 more
wiley   +1 more source

Characterization of Citrus Pectin Oligosaccharides and Their Microbial Metabolites as Modulators of Immunometabolism on Macrophages

, 2021
We characterized the structure of prepared citrus pectin oligosaccharides (POS) and investigated the immunometabolism-modulating effects of POS and their microbial metabolites on human macrophages.
Zhang, S, Hu, H, Pan, S
core   +1 more source

The G-Protein Coupled Formyl Peptide Receptors and Their Role in the Progression of Digestive Tract Cancer

Technology in Cancer Research & Treatment, 2020
Chronic inflammation is a causative factor of many cancers, although it originally acts as a protective host response to the loss of tissue homeostasis. Many inflammatory conditions predispose susceptible cells, most of which are of epithelial origin, to
Cuimeng Tian MD, Keqiang Chen PhD, Wanghua Gong BA, Teizo Yoshimura MD, Jiaqiang Huang PhD, Ji Ming Wang MD, PhD   +5 more
doaj   +1 more source

Leveraging Macrophage Metabolic Reprogramming for Enhanced Anti‐Tumor Immunity

Advanced Science, Volume 13, Issue 33, 15 June 2026.
Tumor‐associated macrophages (TAMs) are key regulators of the tumor microenvironment (TME), with their metabolic states playing a critical role in tumor progression or regression. This review summarizes current understanding of TAM metabolic plasticity alongside cutting‐edge bioengineering innovations, outlining a roadmap for transforming the ...
Zhiyun Liu, Lingyao Zeng, Xulin Gan, Yilin Zhou, Han Shen, Dan Wu, Xin Shou, Minmin Jiang, Liyun Shi   +8 more
wiley   +1 more source

Cancer immunometabolism: advent, challenges, and perspective

Molecular Cancer
For decades, great strides have been made in the field of immunometabolism. A plethora of evidence ranging from basic mechanisms to clinical transformation has gradually embarked on immunometabolism to the center stage of innate and adaptive ...
Qin Dang, Borui Li, Bing Jin, Zeng Ye, Xin Lou, Ting Wang, Yan Wang, Xuan Pan, Qiangsheng Hu, Zheng Li, Shunrong Ji, Chenjie Zhou, Xianjun Yu, Yi Qin, Xiaowu Xu   +14 more
doaj   +1 more source

Integrative Drug‐Target Causal Analysis, Single‐Cell Sequencing and In‐Vivo Validation for Dissecting Molecular Mechanisms Underlying Focal Epilepsy

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
Through Mendelian randomization analysis of the quantitative trait locus data, we identified that four drug targets, namely CASP1, FST, IL10RA, and SUCNR1, have significant genetic associations with the risk of focal epilepsy. This analysis provides preliminary genetic evidence for the causal mechanism by which these targets are involved in the onset ...
Huaiyu Sun, Xuewei Li, Weixuan Zhao, Hongmei Meng, Wuqiong Zhang   +4 more
wiley   +1 more source

Quercetin Inhibits Orthodontic Tooth Movement‐Associated Periodontitis by Regulating Macrophage Aerobic Glycolysis Through the IL‐17/Hippo/YAP Axis

Clinical and Experimental Dental Research, Volume 12, Issue 3, June 2026.
ABSTRACT Objectives Orthodontic tooth movement (OTM) is frequently accompanied by inflammatory responses, including periodontitis, which may compromise treatment outcomes. This study investigated the protective role of quercetin, a natural flavonoid, in OTM‐associated periodontitis and its underlying mechanism involving macrophage metabolic ...
Fen Yao, Zhiping Song, Wuchao Wu, Bingqian Liu, Rongqi Xia, Yao Zhou, Wenxia Wang, Yujie Chen, Zhengyu Liao   +8 more
wiley   +1 more source

B cell immunometabolism in health and disease

B cells have crucial roles in the initiation and progression of many pathological conditions, and several therapeutic strategies have targeted the function of these cells. The advent of immunometabolism has provided compelling evidence that the metabolic
Pucillo, Carlo Ennio Michele, La Cava, Antonio, Colamatteo, Alessandra, Matarese, Giuseppe, Martinis, Eleonora, Tonon, Silvia   +5 more
core   +1 more source