Results 101 to 110 of about 12,525 (189)

PPARγ mediated enhanced lipid biogenesis fuels Mycobacterium tuberculosis growth in a drug-tolerant hepatocyte environment

open access: yeseLife
Mycobacterium tuberculosis (Mtb) infection of the lungs, besides producing prolonged cough with mucus, also causes progressive fatigue and cachexia with debilitating loss of muscle mass.
Binayak Sarkar   +13 more
doaj   +1 more source

Post‐Tuberculosis Lung Disease: Clinicopathologic Insights, Diagnosis, Prevention, and Management

open access: yesMedComm, Volume 7, Issue 10, October 2026.
A comprehensive review on post‐tuberculosis lung disease (PTLD) addresses the epidemiology, pathogenesis, clinical phenotypes and management, risk factors, prevention and systems approach, and future directions. This review provides standardized definitions, mechanistic insights and biomarkers of PTLD development, and clinical strategies for PTLD ...
Radha Gopalaswamy, Selvakumar Subbian
wiley   +1 more source

HPV vaccination improves immune response in children with respiratory papillomatosis

open access: yesScientific Reports
Recurrent respiratory papillomatosis (RRP) is a pathology characterized by the presence of neoplasm in the epithelium of the airways, where the larynx is the main affected organ. The cause of this disease is the low-risk Human Papillomavirus (HPV), where
Miguel A. Prieto-Islas   +7 more
doaj   +1 more source

Brown Adipose Tissue: Molecular Mechanisms of Regulation, Physiological Functions, and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 10, October 2026.
This review systematically covers three core dimensions of brown adipose tissue (BAT): multilayered regulatory mechanisms governing brown adipocyte differentiation and phenotypic identity, physiological functions and signaling pathways in mediating thermogenesis and systemic metabolic crosstalk between BAT and multiple organs, and emerging clinical in ...
Xiaoli Deng   +4 more
wiley   +1 more source

Aging of Skeletal Muscle: From Molecular Mechanisms to Therapeutic Interventions

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Skeletal muscle aging is driven by coordinated local breakdown across myofibers, stem and stromal cells, immune and vascular compartments, and neuromuscular control. These mechanisms promote mitochondrial dysfunction, inflammation, senescence, impaired regeneration, fibrosis, myosteatosis, denervation, and functional decline.
Ting Liu, Yaomin Hu
wiley   +1 more source

Immunometabolism: another road to sepsis and its therapeutic targeting

open access: yes, 2018
Sepsis is a major health problem all over the world. Despite its existence since the time of Hippocrates (470\ua0BC), sepsis is still a serious medical problem for physicians working in both pediatric and adult intensive care units.
Kumar, Vijay
core   +1 more source

Alveolar Macrophages: Development, Respiratory Homeostasis, Signal Pathways, Diseases, and Therapeutic Opportunities

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Alveolar macrophages: development, respiratory homeostasis, signal pathways, diseases, and therapeutic opportunities: During embryonic development, fetal progenitors migrate to the developing lungs via a CX3CR1‐dependent mechanism to establish the TrAM pool.
Sihan Yang   +4 more
wiley   +1 more source

Glutamine Metabolism in Health and Diseases

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Glutamine metabolism acts as a metabolic hub connecting cellular stress adaptation, immune regulation, and disease development. Through regulating energy production, biosynthesis, redox balance, and nitrogen metabolism, glutamine supports cellular homeostasis under physiological and pathological conditions.
Yi Ding   +3 more
wiley   +1 more source

Liver Metastases from Colorectal Cancer: From Pathogenesis to Current Treatment

open access: yesMedComm, Volume 7, Issue 10, October 2026.
The liver is not merely a passive recipient of disseminated tumor cells, but a unique metastatic organ shaped by anatomical, metabolic, and immunological characteristics that support tumor colonization. Increasing evidence indicates that colorectal cancer liver metastasis development is driven by dynamic interactions between tumor intrinsic programs ...
Jialiang Fan   +10 more
wiley   +1 more source

The metabolism-immunity axis in Immune thrombocytopenia: from energy regulation to targeted therapy

open access: yesPharmacological Research
Immunometabolism has received significant interest as a field exploring the dynamic interation between the immune system and metabolic processes. Immune cell activation, proliferation, and function are tightly regulated by metabolism, and metabolic ...
Xin Zhou, Ning-ning Shan
doaj   +1 more source

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