Results 111 to 120 of about 10,784 (232)

Pro‐ and Anti‐Inflammatory Macrophages Adjust UCP2 Protein Levels Based on Their Intrinsic Metabolism and Available Metabolites

open access: yesEuropean Journal of Immunology, Volume 56, Issue 6, June 2026.
LPS‐stimulated macrophages exhibit high glycolytic flux, with pyruvate preferentially converted to lactate even under normoglycemic conditions, limiting pyruvate availability for the tricarboxylic acid (TCA) cycle and reducing oxygen consumption rate (OCR).
Jila Nasirzade   +8 more
wiley   +1 more source

Mesenteric Adipose Tissue as a Modulator of Intestinal Inflammation: Mechanistic Insights and Model Systems in Crohn's Disease

open access: yesEuropean Journal of Immunology, Volume 56, Issue 6, June 2026.
This review explores how mesenteric adipose tissue, particularly creeping fat, contributes to intestinal inflammation through dysregulated adipokine signalling. We explore how metabolic stress alters immune‐adipose interactions and promotes disease progression.
Toka Omar   +2 more
wiley   +1 more source

Exacerbated Hepatic Stress and Systemic Metabolic Disruption Driven by SARS‐CoV‐2 P.1 Variant in K18‐hACE2 Mice

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 6, June 2026.
ABSTRACT Introduction While severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has been extensively studied in the context of pulmonary disease, its impact on metabolic organs remains poorly understood, particularly across experimental models.
Monara Kaélle Sérvulo Cruz Angelim   +9 more
wiley   +1 more source

Involvement of Gut Microbiota, Microbial Metabolites and Interaction with Polyphenol in Host Immunometabolism

open access: yes, 2020
Immunological and metabolic processes are inextricably linked and important for maintaining tissue and organismal health. Manipulation of cellular metabolism could be beneficial to immunity and prevent metabolic and degenerative diseases including ...
Yawen Zhou   +3 more
core   +1 more source

The Role and Therapeutic Potential of Voltage‐Gated Potassium Channel Kv1.3 in Metabolism‐Related Disorders

open access: yesiNew Medicine, Volume 2, Issue 2, June 2026.
ABSTRACT Over the past three decades, the global burden of common metabolic diseases such as obesity, diabetes, and atherosclerosis has steadily increased, becoming a serious public health issue that poses a major threat to human health worldwide. Potassium channels, particularly the voltage‐gated Kv1.3 subtype, serve as critical regulators of cellular
Wenjun Zhen   +6 more
wiley   +1 more source

Immunometabolism: another road to sepsis and its therapeutic targeting

open access: yes, 2018
Sepsis is a major health problem all over the world. Despite its existence since the time of Hippocrates (470\ua0BC), sepsis is still a serious medical problem for physicians working in both pediatric and adult intensive care units.
Kumar, Vijay
core   +1 more source

Metabolic regulation of the immune system in health and diseases: mechanisms and interventions

open access: yesSignal Transduction and Targeted Therapy
Metabolism, including glycolysis, oxidative phosphorylation, fatty acid oxidation, and other metabolic pathways, impacts the phenotypes and functions of immune cells.
Tengyue Hu   +6 more
doaj   +1 more source

Acknowledgement to Reviewers of Immunometabolism in 2020

open access: yes, 2021
The Immunometabolism Editorial Office
core   +1 more source

Targeting macrophage immunometabolism: dawn in the darkness of sepsis

open access: yes, 2018
Sepsis is known since the time (470 BC) of great Greek physician, Hippocrates. Advancement in modern medicine and establishment of separate branches of medical science dealing with sepsis research have improved its outcome.
V. Kumar, Kumar, V.
core   +1 more source

Mapping Immunity With Cutting‐Edge Spatial Biology and Tissue Cytometry Innovations

open access: yesMedComm, Volume 7, Issue 6, June 2026.
This review explores how spatial biology integrates multiplexed imaging and tissue cytometry to reveal immune organization within native tissue contexts. ABSTRACT The immune system operates within organized tissue landscapes, where spatial relationships between cells shape the nature and outcome of immune responses.
Lilibeth Cárdenas‐Piedra   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy