Results 71 to 80 of about 48,894 (301)

Immunomodulators Inspired by Nature: A Review on Curcumin and Echinacea

Molecules, 2018
The immune system is an efficient integrated network of cellular elements and chemicals developed to preserve the integrity of the organism against external insults and its correct functioning and balance are essential to avoid the occurrence of a great ...
Michele Catanzaro, Emanuela Corsini, Michela Rosini, Marco Racchi, Cristina Lanni   +4 more
doaj   +1 more source

Disease‐Stage Synchronized Nanozyme Therapy for Polymicrobial Sepsis through Adaptive Catalytic and Immune Reprogramming

Advanced Science, EarlyView.
A disease‐stage synchronized nanozyme platform is developed to treat polymicrobial sepsis by adapting its functions to changing infection environments. The system eliminates multidrug‐resistant bacteria during early infection while reducing inflammation and restoring immune balance during recovery, providing an integrated strategy for infection control
Anlai Zou, Xiaoxue Zhu, Runhan Zhu, Chengchu Xue, Qinyu Zhang, Mengke Li, Ting Yu, Yuzhen Gao, Zhi Ruan, Ying Fu, Yunlei Xianyu, Jun Zhang   +11 more
wiley   +1 more source

A potent trypanocidal component from the fungus Lentinus strigosus inhibits trypanothione reductase and modulates PBMC proliferation

Memorias do Instituto Oswaldo Cruz, 2008
The fungus Lentinus strigosus (Pegler 1983) (Polyporaceae, basidiomycete) was selected in a screen for inhibitory activity on Trypanosoma cruzi trypanothione reductase (TR). The crude extract of L. strigosus was able to completely inhibit TR at 20 µg/ml.
Betania Barros Cota, Luiz Henrique Rosa, Elaine Maria Souza Fagundes, Olindo Assis Martins-Filho, Rodrigo Correa-Oliveira, Alvaro José Romanha, Carlos Augusto Rosa, Carlos Leomar Zani   +7 more
doaj   +1 more source

Immunopterin: A prospective therapy and preventative to fight COVID-19?

Pteridines, 2022
The authors explore the therapeutic and prophylactic efficacies of Immunopterin (calcium pterin-6-carboxylate chelate) against coronavirus colds and as a therapy against COVID-19.
Moheno Phillip B. B., Fuchs Dietmar
doaj   +1 more source

Comparison of baseline characteristics based on concomitant immunomodulators or corticosteroids.

, 2019
Comparison of baseline characteristics based on concomitant immunomodulators or corticosteroids.
Noriko Kamata (2159683), Yasuaki Nagami (3632935), Hirokazu Yamagami (482330), Tetsuya Tanigawa (482325), Koji Otani (645949), Yasuhiro Fujiwara (309173), Koichi Taira (3632938), Yu Nishida (3632941), Shigehiro Itani (6383807), Fumio Tanaka (621542), Tomomi Yukawa (3632929), Toshio Watanabe (151136), Shuhei Hosomi (3632932), Naoko Sugita (6433358)   +13 more
core   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

Immunomodulators in leprosy: A narrative review [PDF]

Background: Leprosy is a chronic infectious disease caused by Mycobacterium leprae. Current therapeutic regimen, like the multidrug therapy (MDT), are effective in treating most cases, but new cases continue to emerge in Indonesia every year.
Esti, Prima Kartika, Kimberly, Kesya, Ferina, Siti Aisha Nabila   +2 more
core   +1 more source

Natural‐Inspired Engineered Microalgae With Selenium Enrichment Enabled Potent Anti‐Tumor Immunity

Advanced Science, EarlyView.
Se‐Ssp was engineered as a potent immunomodulator for activating innate immunity via the TLR and cGAS‐STING pathways, therefore converting “cold” tumors into “hot” tumors to achieve high efficacy and long‐term therapeutic outcomes. ABSTRACT Immunotherapy has shed light on clinical oncology for several decades.
Yuqi Yang, Xiaowei Cai, Xiaoyan Zhong, Tian Qiu, Qinwei Lu, Jiahao Qin, Fei Gong, Yecheng Huang, Chenyu Jiang, Youdong Chen, Yuan Cheng, Liang Cheng   +11 more
wiley   +1 more source

Melatonin: clinical prospects in immunology

Journal of V. N. Karazin Kharkiv National University: Series Medicine, 2020
Introduction. For a long time, HIV has been associated with a number of inflammatory, infectious and neoplastic skin diseases. In the era of anti-retroviral therapy researchers have found even more about the relationship between skin disease and chronic ...
Tetiana Liadova, Mykola Popov, Diana Dorosh   +2 more
doaj   +1 more source

HPV-Specific Immunotherapy: Key Role for Immunomodulators

, 2014
Cervical cancer is the second most common malignancy among women worldwide. The prime causal factor of the disease is a persistent infection with human papillomavirus (HPV) with individuals failing to mount a sufficient immune response against the virus.
Nijman, Hans W., Daemen, Toos, Daemen, Toos; id_orcid, Van de Wall, Stephanie   +3 more
core   +1 more source