Results 11 to 20 of about 19,820 (199)
Immunopathogenesis of osteoarthritis [PDF]
Clinical Immunology, 2013 Even though osteoarthritis (OA) is mainly considered as a degradative condition of the articular cartilage, there is increasing body of data demonstrating the involvement of all branches of the immune system. Genetic, metabolic or mechanical factors cause an initial injury to the cartilage resulting in release of several cartilage specific auto ...
Abdul, Haseeb, Tariq M, Haqqi
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Immunopathogenesis of atherosclerosis [PDF]
Journal of Leukocyte Biology, 2004 AbstractRecent clinical studies indicate that the number of microbial infections (the “pathogen burden”) critically determines the development and progression of atherosclerotic disease. Viruses or bacteria with a specific tropism for cells of the vascular wall may contribute to the initial vascular injury via direct cytopathic effects or via the ...
Ludewig B, Krebs P, Scandella E
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Immunopathogenesis of pancreatitis [PDF]
Mucosal Immunology, 2017 The conventional view of the pathogenesis of acute and chronic pancreatitis is that it is due to a genetic- or environment-based abnormality of intracellular acinar trypsinogen activation and thus to the induction of acinar cell injury that, in turn, sets in motion an intra-pancreatic inflammatory process.
T, Watanabe, M, Kudo, W, Strober
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AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Immunopathogenesis of AIDS [PDF]
Current Infectious Disease Reports, 2009 Twenty-five years after the discovery of HIV as the cause of AIDS, tremendous progress has been made in reducing the morbidity and mortality associated with this disease. However, there is still neither a cure nor a vaccine for HIV infection. This shortcoming is likely a consequence of our incomplete understanding of the mechanisms of AIDS pathogenesis,
Alexandra M, Ortiz, Guido, Silvestri
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Periodontology 2000, EarlyView., 2023 Abstract This narrative review summarizes the collective knowledge on periodontal microbiology, through a historical timeline that highlights the European contribution in the global field. The etiological concepts on periodontal disease culminate to the ecological plaque hypothesis and its dysbiosis‐centered interpretation.
Georgios N. Belibasakis +5 more
wiley +1 more source
eLife, 2015 The HIV-1 envelope protein gp120 is both the target of neutralizing antibodies and a major focus of vaccine efforts; however how it is delivered to B cells to elicit an antibody response is unknown.
Chung Park +3 more
doaj +1 more source
Viruses, 2022 Macrophages in the kidney play a pathogenic role in inflammation and fibrosis. Our study aimed to understand the polarisation of the M1 and M2 phenotypic profiles of macrophages in injured kidney tissue retrieved from fatal cases of yellow fever virus ...
Juliana Marinho Melo +11 more
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Immunopathogenesis of Rheumatoid Arthritis [PDF]
Immunity, 2017 Rheumatoid arthritis (RA) is the most common inflammatory arthropathy. The majority of evidence, derived from genetics, tissue analyses, models, and clinical studies, points to an immune-mediated etiology associated with stromal tissue dysregulation that together propogate chronic inflammation and articular destruction. A pre-RA phase lasting months to
Firestein, Gary S., McInnes, Iain B.
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Scanning the Immunopathogenesis of Psoriasis [PDF]
International Journal of Molecular Sciences, 2018 Psoriasis is a chronic inflammatory skin disease, the immunologic model of which has been profoundly revised following recent advances in the understanding of its pathophysiology. In the current model, a crosstalk between keratinocytes, neutrophils, mast cells, T cells, and dendritic cells is thought to create inflammatory and pro-proliferative ...
CHIRICOZZI, ANDREA +4 more
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