Results 151 to 160 of about 5,882 (203)

Piplartine as an Innovative Natural Product With Dual Antiparasitic and Immunomodulatory Actions. [PDF]

J Immunol Res
Fukui-Silva L, Souza FCR, Amorim CS, de Moraes J.   +3 more
europepmc   +1 more source

Inhibition of Aurora B induces senescence and potentiates immunotherapy in hepatocellular carcinoma. [PDF]

Cell Oncol (Dordr)
Wu S, Wang H, Yu C, Yang C, Cheng X, Liao L, Cao Y, Qin W, Ma X.   +8 more
europepmc   +1 more source

Proteasome: Role in T Cell Function Regulation. [PDF]

Int J Biol Sci
Tang D, Wu X, Lei JH, Qiao Y, Deng CX.
europepmc   +1 more source

The immunoproteasome as a neuroimmune hub in the central nervous system: from proteostasis stress to inflammatory pathology. [PDF]

J Neuroinflammation
Zhao H, Liu Y, Chen X.
europepmc   +1 more source

Immunoproteasome remodeling in senescing human macrophages reveals the loss of PA28αβ capping as a hallmark of immunosenescence. [PDF]

Commun Biol
Monittola F, Masini S, Montanari M, Nasoni MG, Bianchi M, De Matteis R, Ricci A, Ligi D, Luchetti F, Canonico B, Magnani M, Menotta M, Fraternale A, Crinelli R.   +13 more
europepmc   +1 more source

Aberrant SUMOylation Restricts the Targetable Cancer Immunopeptidome. [PDF]

Adv Sci (Weinh)
Demel UM, Meurer A, Zaghla BKQ, Atay B, Steiert D, Hummel LV, Isaakidis K, Zang C, Korenkov M, Schielin M, Yousefian S, Mecklenbräuker S, Kirchner M, Haas S, Busse A, Mertins P, Müller S, Wirth M, Klatt MG, Keller U.   +19 more
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Cytokine-Mediated Plasticity in the Molecular Requirements for Peptide-Loading Complex Formation and Antigen Presentation. [PDF]

Cells
Aranha R, Dastpeyman M, Pandey K, Dorvash M, Ayala R, Croft NP, Purcell AW.   +6 more
europepmc   +1 more source

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Immunoproteasomes and immunosenescence

Ageing Research Reviews, 2003
Aging is a complex process which is accompanied with the decline and the reshaping of different functions of the body. In particular the immune system is characterized, during ageing (immunosenescence) by a remodeling of innate immunity (well preserved, up-regulated) and clonotypical immunity (severely altered) and by the occurrence of a chronic ...
Mishto M., Santoro A., Bellavista E., Bonafe M., Monti D., Franceschi C.   +5 more
openaire   +3 more sources

Proteasomes and immunoproteasomes.

Rivista di biologia, 2011
In eukaryotic cells, the protein degradation is a highly regulated and selective process. Membrane-associated or extracellular proteins are degraded in lysosomes, whereas intracellular protein dismantling is primarily non-lysosomal, being realized by complex, not-membrane enclosed and energy-dependent effectors, the proteasomes, localized in both ...
Fietta, Pieranna, Delsante, Giovanni
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The immunoproteasome

American Journal of Transplantation, 2017
Modern treatment strategies for the maintenance of allograft acceptance frequently target ubiquitously-expressed pathways, leading to significant side-effects and poor long-term allograft outcomes. Constitutive proteasome inhibitors, which have recently been introduced for the treatment of antibody-mediated rejection, target the ubiquitously-expressed ...
Eskandari, S. K., Seelen, M. A. J., Lin, G., Azzi, J. R.   +3 more
openaire   +1 more source