Results 171 to 180 of about 29,033 (245)

Who Can Safely Discontinue Treatment in Myasthenia Gravis? Insights From a Long‐Term Real‐World Study

open access: yesEuropean Journal of Neurology, Volume 33, Issue 3, March 2026.
This prospective cohort study identifies independent predictors of relapse following complete treatment discontinuation in 196 myasthenia gravis (MG) patients who achieved minimal symptom expression (MSE). Cox regression analysis revealed late‐onset MG (age ≥ 50 years) as a risk factor, while rituximab therapy, longer treatment duration, and extended ...
Dingxian He   +7 more
wiley   +1 more source

Immunosenescence and susceptibility to respiratory viruses: a state-of-the-art review. [PDF]

open access: yesEur Respir Rev
Fragkou PC   +8 more
europepmc   +1 more source

Sex Matters: Hormonal and Chromosomal Determinants of Autoimmunity and Anti‐Cancer Immunity Across the Lifespan

open access: yesImmunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Sex plays a key role in shaping both anti‐cancer immunity and autoimmunity. Biological factors underlying sexual dimorphism have now been identified in multiple aspects of anti‐cancer immunity and autoimmunity. These factors include sex differences in hormone levels, chromosome complement, and expression of the long non‐coding RNA XIST.
Christian G. Bustillos   +4 more
wiley   +1 more source

Therapeutic advances in pruritus as a model of personalized medicine

open access: yesJournal of the European Academy of Dermatology and Venereology, Volume 40, Issue 3, Page 415-422, March 2026.
Recent advances in itch biology reveal that chronic pruritus arises from distinct neuroimmune pathways driven by cytokines, JAK, BTK and GPCRs. Targeted biologics and small molecule inhibitors such as dupilumab, nemolizumab, remibrutinib and JAK inhibitors precisely modulate these pathways, leading to a new era of personalized therapeutics in pruritus.
Kelsey Auyeung   +2 more
wiley   +1 more source

Age‐Dependent Increase in Small Intestinal Permeability and Sex‐Dependent Absorptive Capacity in Cats (Felis catus)

open access: yesJournal of Animal Physiology and Animal Nutrition, Volume 110, Issue 2, Page 169-176, March 2026.
ABSTRACT Age‐associated changes in intestinal permeability and function have not been studied in domestic cats, leaving a key factor in the relationship between age and digestive health in cats unexplored. Due to factors not currently understood, mature and senior cats may experience a loss of fat and protein digestibility, along with a loss of body ...
Keely Patterson   +6 more
wiley   +1 more source

Aging‐Driven Inter‐Organ Crosstalk in Postmenopausal Osteoporosis: From Immunometabolic Drift to Multisystem Frailty

open access: yesThe FASEB Journal, Volume 40, Issue 4, 28 February 2026.
Postmenopausal osteoporosis (PMOP) is increasingly recognized as an aging‐associated, multisystem state of fragility, in which estrogen deficiency exacerbates immune and metabolic drift across the bone marrow, skeletal muscle, adipose tissue, gut, vascular system, and neural circuits.
Xianlin Rao, Xiaoyu Cai
wiley   +1 more source

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