Results 151 to 160 of about 29,526 (256)
Modeling of immune life history and body growth: the role of antigen burden [PDF]
In this paper, a recently developed mathematical model of age related changes in population of peripheral T cells (Romanyukha, Yashin, 2003) is used to describe ontogenetic changes of the immune system.
Alexei A. Romanyukha +2 more
core
T Cell Immunosenescence in Inflammatory Skin Diseases: Pathogenesis and Therapeutic Targets
Aging Cell, Volume 25, Issue 5, May 2026.Immunosenescent T cells promote inflammatory skin diseases such as psoriasis, atopic dermatitis, rosacea, and seborrheic dermatitis via hyperactive signaling networks and SASP secretion. Consequently, intercepting downstream SASP, inhibiting internal pathways, or utilizing senolytics represents promising therapeutic interventions.
Conghui Liu +3 more
wiley +1 more source
Age is the work of art? : impact of neutrophil and organism age on neutrophil extracellular trap formation [PDF]
, 2017 Elzbieta Kolaczkowska, Weronika Ortmann
core +1 more source
Aged Gut Microbiota Induces Mucosal Transcriptional Dysregulation, Impairing Immune Surveillance
Aging Cell, Volume 25, Issue 5, May 2026.Aging impaired intestinal mucosal immune homeostasis by altering the epithelial barrier, lamina propria immune cells, follicle‐associated epithelium, and gut microbiota. These changes, particularly the accumulation of pro‐inflammatory bacteria in the gut microbiota, are closely associated with dysregulation of follicle‐associated epithelium gene ...
Fang Wu +10 more
wiley +1 more source
Cosmetic Adverse Reactions and Prognostic Factors: A Retrospective Cohort Study in Wuhan, China
Contact Dermatitis, Volume 94, Issue 5, Page 475-481, May 2026.This study reveals that being under 20 or having a history of allergies significantly increases the risk of long‐term symptoms after a cosmetic adverse reaction. These findings help dermatologists identify high‐risk patients for proactive management and tailored preventive strategies.
Ayan Hasen +4 more
wiley +1 more source
Lifelong Exercise as a Modulator of CD4+ T Cell Immunometabolism
European Journal of Clinical Investigation, Volume 56, Issue 5, May 2026.Hypothetical framework illustrating how physical exercise initiated early in life acts as a critical immunomodulatory factor by promoting optimal immune function from childhood and establishing a better “immunometabolic functional peak”. This early advantage may confer sustained benefits to CD4+ T cell metabolism and immune competence across aging ...
Bruna Spolador de Alencar Silva +9 more
wiley +1 more source
Why Is MS a More Frequent Complication of EBV Infection in Females?
Immunological Reviews, Volume 339, Issue 1, May 2026.ABSTRACT Multiple sclerosis (MS) is a T helper (Th) cell‐mediated disease that targets central nervous system (CNS) white matter. This disease affects three times more females than males. For many years, the etiology of MS was not well understood and the exact nature of the autoimmune reaction was speculative.
Shannon E. Dunn +2 more
wiley +1 more source
T Cell Receptor Repertoires Across the Continuum of Vascular, Myocardial, and Age‐Related Diseases
Immunological Reviews, Volume 339, Issue 1, May 2026.ABSTRACT Cardiovascular diseases (CVD) are shaped by a complex interplay with immune mechanisms. In particular, the distinct roles of antigen‐specific T cell mechanisms are emerging as critical determinants across a broad spectrum of conditions, ranging from atherosclerosis, myocardial infarction (MI), heart failure (HF), and myocarditis. Because these
Leon Richter +3 more
wiley +1 more source
Immunosenescence in Human Disease: Mechanistic Insights and Therapeutic Opportunities. [PDF]
Biomol Ther (Seoul)Kim YI +5 more
europepmc +1 more source
Journal of Advanced Nursing, Volume 82, Issue 5, Page 5548-5555, May 2026.ABSTRACT Aim To canvas the contemporary contextual forces within the Australian residential aged care sector and argue for new research and innovation. There is a pressing need to provide systematised, high‐quality and person‐centred care to our ageing populations, especially for those who rely on residential care.
Ramon Z. Shaban +13 more
wiley +1 more source