Results 141 to 150 of about 29,526 (256)
The study corroborates the prognostic value of previously identified risk factors impacting progression‐free survival (PFS) and overall survival (OS) in older patients with extensive‐stage small cell lung cancer (ES‐SCLC). The figure was created with Microsoft PowerPoint.
Jiayin Liu +14 more
wiley +1 more source
ABSTRACT Fusarium spp. are opportunistic fungal pathogens, with an increasing incidence of infection observed in immunocompromised populations. Due to the non‐specific clinical manifestations of cutaneous Fusarium infections, they are often misdiagnosed or overlooked.
Yulin Wang +9 more
wiley +1 more source
ABSTRACT Background and Aim Ferroptosis signaling pathway has been revealed to play a biological role in the tumorigenesis of colorectal cancer (CRC). Our aim was to evaluate the expression pattern and clinical potentials of two ferroptosis‐related genes FSP1 and ACSL4 in colorectal tumors.
Afsaneh Fardsanei +4 more
wiley +1 more source
What's new? This large nation‐wide cohort study provides a comprehensive 20‐year analysis of cancer trends among people living with HIV in France, highlighting persistent excess risks for virus‐related cancers despite effective antiretroviral therapy and immune restoration.
Sophie Grabar +14 more
wiley +1 more source
ABSTRACT Sexually transmitted infections (STIs) remain a major global health threat. A comprehensive assessment of their epidemiological features and future trajectories is essential for informing targeted public health policies and achieving international control targets.
Baigong Feng +5 more
wiley +1 more source
Using data and samples collected from 31 red wolves (Canis rufus) housed at the Red Wolf Propagation Facility in Graham, Washington, this study establishes a narrower and more accurate clinical baseline for 35 haematological and biochemical parameters used in the diagnosis of clinical disease in this critically endangered species.
Heather Broughton +2 more
wiley +1 more source
The discovery of Regulatory T Cells: a long journey toward immune balance and Nobel Prize [PDF]
Anna Calabrò, Calogero Caruso
doaj +1 more source
Aging‐Driven Immunosuppression: The Role of Tregs in the Ovarian Tumor Microenvironment
In the aged ovarian TME, cancer cells exhibit increased succinate production. Elevated extracellular succinate activates the SUCNR1 receptor on Tregs, promoting their recruitment and contributing to an immunosuppressive environment. This leads to diminished anti‐tumor T cell responses and reduced survival.
Mary P. Udumula +10 more
wiley +1 more source
Organ‐specific aging clocks integrating genomics, epigenomics, transcriptomics, proteomics, and metabolomics offer a more accurate assessment of biological aging than single‐omics approaches. This review proposes a multi‐omics framework emphasizing tissue data, longitudinal study designs, and clinically meaningful training outcomes to advance the ...
Maria Vasileiou +3 more
wiley +1 more source
Background People living with HIV (PLHIV) demonstrate accelerated aging and immunosenescence in spite of immune-restoration following long-term antiretroviral treatment (ART).
Ashwini Vinod Shete +9 more
doaj +1 more source

