Results 1 to 10 of about 295,606 (244)
Androgen-Induced Immunosuppression
Frontiers in Immunology, 2018 In addition to determining biological sex, sex hormones are known to influence health and disease via regulation of immune cell activities and modulation of target-organ susceptibility to immune-mediated damage.
Melanie R. Gubbels Bupp +1 more
doaj +2 more sources
Extracellular Vesicles: New Classification and Tumor Immunosuppression
Biology, 2023 Simple Summary Extracellular vesicles (EVs) are cell-derived membrane-surrounded vesicles that carry bioactive molecules and deliver them to recipient cells. Classical EVs are exosomes, microvesicles, and apoptotic bodies.
M. Sheta +3 more
semanticscholar +1 more source
Sepsis-induced immunosuppression: mechanisms, diagnosis and current treatment options
Military Medical Research, 2022 Sepsis is a common complication of combat injuries and trauma, and is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection.
Di Liu +15 more
semanticscholar +1 more source
Critical Care, 2023 Background The development of stratification tools based on the assessment of circulating mRNA of genes involved in the immune response is constrained by the heterogeneity of septic patients.
Maxime Bodinier +12 more
doaj +1 more source
Inflammation Research, 2022 Excessive exposure of the skin to UV radiation (UVR) triggers a remodeling of the immune system and leads to the photoaging state which is reminiscent of chronological aging.
A. Salminen +2 more
semanticscholar +1 more source
Tumor-Associated Macrophages Regulate PD-1/PD-L1 Immunosuppression
Frontiers in Immunology, 2022 Anti-programmed cell death 1 (PD-1) or anti-PD-ligand (L) 1 drugs, as classic immune checkpoint inhibitors, are considered promising treatment strategies for tumors.
Y. Pu, Qing Ji
semanticscholar +1 more source
Annals of Intensive Care, 2022 Background Lymphopenia is a hallmark of severe coronavirus disease 19 (COVID-19). Similar alterations have been described in bacterial sepsis and therapeutic strategies targeting T cell function such as recombinant human interleukin 7 (rhIL-7) have been ...
Frank Bidar +17 more
doaj +1 more source
Lactate-Lactylation Hands between Metabolic Reprogramming and Immunosuppression
International Journal of Molecular Sciences, 2022 Immune evasion and metabolic reprogramming are two fundamental hallmarks of cancer. Interestingly, lactate closely links them together. However, lactate has long been recognized as a metabolic waste product.
Lihua Chen +5 more
semanticscholar +1 more source
Exosome-Mediated Immunosuppression in Tumor Microenvironments
Cells, 2022 Exosomes are membranous structures secreted by nearly all cell types. As critical messengers for intercellular communication, exosomes deliver bioactive cargoes to recipient cells and are involved in multiple physiopathological processes, including ...
Qihui Xie +6 more
semanticscholar +1 more source