Results 11 to 20 of about 521,863 (391)
Sepsis-induced immunosuppression: mechanisms, biomarkers and immunotherapy [PDF]
Frontiers in ImmunologySepsis, a life-threatening organ dysfunction resulting from a dysregulated host response to infection, initiates a complex immune response that varies over time, characterized by sustained excessive inflammation and immunosuppression.
Xun Gao +7 more
doaj +2 more sources
The Effect of Immunosuppressive Treatment on Torque Teno Virus Load in Lung Transplant Recipients: A Preliminary Study [PDF]
VirusesAfter transplantation, systematically monitoring and assessing the risk of transplanted organ rejection is crucial. Current methods involving immunosuppressant monitoring, the assessment of organ function, and biopsies are insufficient for predicting ...
Marek Ochman +8 more
doaj +2 more sources
Annals of Intensive Care, 2022 Background Although multiple individual immune parameters have been demonstrated to predict the occurrence of secondary infection after critical illness, significant questions remain with regards to the selection, timing and clinical utility of such ...
Jan-Alexis Tremblay +12 more
doaj +1 more source
Frontiers in Immunology, 2022 BackgroundMucormycosis is a deadly fungal infection that mainly affects severely immunocompromised patients. We report herein the case of a previously immunocompetent adult woman who developed invasive cutaneous mucormycosis after severe burn injuries ...
Dina M. Tawfik +22 more
doaj +1 more source
Effect of Immunosuppression on the Immunogenicity of mRNA Vaccines to SARS-CoV-2
Annals of Internal Medicine, 2021 Evidence suggests that immunogenicity to mRNA-based SARS-CoV-2 vaccination in immunosuppressed patients may be reduced. This study assessed the response to 2 doses of mRNA-based SARS-CoV-2 vaccine among 133 participants with underlying chronic ...
P. Deepak +39 more
semanticscholar +1 more source
Frontiers in Immunology, 2021 Sepsis is a worldwide health priority characterized by the occurrence of severe immunosuppression associated with increased risk of death and secondary infections.
Astrid Fabri +18 more
doaj +1 more source
Melanoma and Immunosuppression [PDF]
Dermatology, 2009 In a recent article, Richtig et al. [1] suggested that immunosuppression may be a risk factor for melanoma development and, in order to support this view, cited a study demonstrating an increased frequency of melanoma in organ transplant recipients receiving long-term immunosuppression [2] .
Belloni Fortina A +4 more
openaire +4 more sources
Frontiers in Medicine, 2022 BackgroundNovel biomarkers are needed to progress toward individualized patient care in sepsis. The immune profiling panel (IPP) prototype has been designed as a fully-automated multiplex tool measuring expression levels of 26 genes in sepsis patients to
Louis Kreitmann +25 more
doaj +1 more source
Pharmacotherapy, 2022 Advances in maintenance immunosuppression over the past three decades have improved solid organ transplantation outcomes dramatically. Uninterrupted access to immunosuppression is paramount to minimize rejection and maintain allograft and patient ...
J. Nelson +11 more
semanticscholar +1 more source
Sepsis-Induced Immunosuppression.
Annual Review of Physiology, 2021 Sepsis is expected to have a substantial impact on public health and cost as its prevalence increases. Factors contributing to increased prevalence include a progressively aging population, advances in the use of immunomodulatory agents to treat a rising
L. Torres, P. Pickkers, T. van der Poll
semanticscholar +1 more source