Results 11 to 20 of about 453,253 (341)

Immunosuppressants

open access: yesJournal of the California Dental Association, 2008
This paper provides a brief introduction to some of the common immunosuppressants used in oral medicine, the prevention and treatment of oral adverse effects of immunosuppressants, and considerations for dental treatment in patients taking immunosuppressants.
Nita, Chainani-Wu, Timothy C, Wu
openaire   +2 more sources

Dynamic LTR retrotransposon transcriptome landscape in septic shock patients

open access: yesCritical Care, 2020
Background Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection. Numerous studies have explored the complex and dynamic transcriptome modulations observed in sepsis patients, but a large fraction ...
Marine Mommert   +15 more
doaj   +1 more source

Herpes DNAemia and TTV Viraemia in Intensive Care Unit Critically Ill Patients: A Single-Centre Prospective Longitudinal Study

open access: yesFrontiers in Immunology, 2021
IntroductionWe analysed blood DNAemia of TTV and four herpesviruses (CMV, EBV, HHV6, and HSV-1) in the REAnimation Low Immune Status Marker (REALISM) cohort of critically ill patients who had presented with either sepsis, burns, severe trauma, or major ...
François Mallet   +18 more
doaj   +1 more source

Antilymphoid antibody preconditioning and tacrolimus monotherapy for pediatric kidney transplantation [PDF]

open access: yes, 2006
Objective: Heavy post-transplant immunosuppression may contribute to long-term immunosuppression dependence by subverting tolerogenic mechanisms; thus, we sought to determine if this undesirable consequence could be mitigated by pretransplant lymphoid ...
Abhay N. Vats   +52 more
core   +1 more source

Pediatric Liver Transplantation: Then and Now [PDF]

open access: yes, 2020
This paper reviews the past 50 years of liver transplantation in children from the perspective of patient demographics, perioperative patient management, surgical techniques, immunosuppression and patient ...
Banh, DPT   +4 more
core   +1 more source

Monocytic HLA-DR expression kinetics in septic shock patients with different pathogens, sites of infection and adverse outcomes

open access: yesCritical Care, 2020
Background Decreased monocytic (m)HLA-DR expression is the most studied biomarker of sepsis-induced immunosuppression. To date, little is known about the relationship between sepsis characteristics, such as the site of infection, causative pathogen, or ...
Guus P. Leijte   +8 more
doaj   +1 more source

Monocyte Trajectories Endotypes Are Associated With Worsening in Septic Patients

open access: yesFrontiers in Immunology, 2021
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. The immune system plays a key role in sepsis onset and remains dysregulated over time in a heterogeneous manner.
Maxime Bodinier   +16 more
doaj   +1 more source

Platelet-Activating Factor-Induced Reduction in Contact Hypersensitivity Responses Is Mediated by Mast Cells via Cyclooxygenase-2-Dependent Mechanisms [PDF]

open access: yes, 2018
Platelet-activating factor (PAF) stimulates numerous cell types via activation of the G protein-coupled PAF receptor (PAFR). PAFR activation not only induces acute proinflammatory responses, but it also induces delayed systemic immunosuppressive effects ...
FitzGerald, Garret A.   +6 more
core   +1 more source

A 9-mRNA signature measured from whole blood by a prototype PCR panel predicts 28-day mortality upon admission of critically ill COVID-19 patients

open access: yesFrontiers in Immunology, 2022
Immune responses affiliated with COVID-19 severity have been characterized and associated with deleterious outcomes. These approaches were mainly based on research tools not usable in routine clinical practice at the bedside. We observed that a multiplex
Claire Tardiveau   +39 more
doaj   +1 more source

Transcriptome modulation by hydrocortisone in severe burn shock: ancillary analysis of a prospective randomized trial

open access: yesCritical Care, 2017
Background Despite shortening vasopressor use in shock, hydrocortisone administration remains controversial, with potential harm to the immune system. Few studies have assessed the impact of hydrocortisone on the transcriptional response in shock, and we
Jonathan Plassais   +7 more
doaj   +1 more source

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