Results 11 to 20 of about 392,479 (342)
Frontiers in Immunology, 2021 Sepsis is a worldwide health priority characterized by the occurrence of severe immunosuppression associated with increased risk of death and secondary infections.
Astrid Fabri +18 more
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Frontiers in Medicine, 2022 BackgroundNovel biomarkers are needed to progress toward individualized patient care in sepsis. The immune profiling panel (IPP) prototype has been designed as a fully-automated multiplex tool measuring expression levels of 26 genes in sepsis patients to
Louis Kreitmann +25 more
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Ferroptosis in immunostimulation and immunosuppression
Immunological Reviews, 2023 Ferroptosis is a form of iron‐dependent regulated cell death characterized by the accumulation of toxic lipid peroxides, particularly in the plasma membrane, leading to lytic cell death. While it plays a crucial role in maintaining the overall health and
D. Tang, G. Kroemer, Rui Kang
semanticscholar +1 more source
Inflammatory macrophages reprogram to immunosuppression by reducing mitochondrial translation
Nature Communications, 2023 Acute inflammation can either resolve through immunosuppression or persist, leading to chronic inflammation. These transitions are driven by distinct molecular and metabolic reprogramming of immune cells.
Marlies Cortés +17 more
semanticscholar +1 more source
Critical Care, 2019 Background Sepsis is the leading cause of mortality for critically ill patients worldwide. Patients develop T lymphocyte dysfunctions leading to T-cell exhaustion associated with increased risk of death.
Julie Mouillaux +10 more
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Frontiers in Immunology, 2022 A majority of patients with sepsis surviving the first days in intensive care units (ICU) enter a state of immunosuppression contributing to their worsening.
Morgane Crausaz +11 more
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Journal of the California Dental Association, 2008 This paper provides a brief introduction to some of the common immunosuppressants used in oral medicine, the prevention and treatment of oral adverse effects of immunosuppressants, and considerations for dental treatment in patients taking immunosuppressants.
Nita, Chainani-Wu, Timothy C, Wu
openaire +2 more sources
Dynamic LTR retrotransposon transcriptome landscape in septic shock patients
Critical Care, 2020 Background Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection. Numerous studies have explored the complex and dynamic transcriptome modulations observed in sepsis patients, but a large fraction ...
Marine Mommert +15 more
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Frontiers in Immunology, 2021 IntroductionWe analysed blood DNAemia of TTV and four herpesviruses (CMV, EBV, HHV6, and HSV-1) in the REAnimation Low Immune Status Marker (REALISM) cohort of critically ill patients who had presented with either sepsis, burns, severe trauma, or major ...
François Mallet +18 more
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Exosomal PD-L1 Contributes to Immunosuppression and is Associated with anti-PD-1 Response
Nature, 2018 Tumour cells evade immune surveillance by upregulating the surface expression of programmed death-ligand 1 (PD-L1), which interacts with programmed death-1 (PD-1) receptor on T cells to elicit the immune checkpoint response1,2.
Gang Chen +44 more
semanticscholar +1 more source