Results 201 to 210 of about 521,863 (391)

Sepsis-induced immunosuppression: from cellular dysfunctions to immunotherapy

Nature reviews. Immunology, 2013
R. Hotchkiss, G. Monneret, D. Payen
semanticscholar   +1 more source

ORL@Cu‐MOF Boost Cuproptosis and Suppress Fatty Acid Metabolism for Cancer Lymph Node Metastasis Synergistic Therapy

Advanced Science, EarlyView.
The fabrication of ORL@Cu‐MOF and the mechanism of synergistic therapy by cuproptosis, reprogram fatty acid metabolism and anti‐PD‐1. Abstract Lymph node metastasis (LNM) is one of the significant characteristics of poor prognosis in oral squamous cell carcinoma (OSCC), strongly associated with high mortality rates.
Zi‐Zhan Li, Yi Liu, Kan Zhou, Lei‐Ming Cao, Guang‐Rui Wang, Jinmei Wu, Yi‐Fu Yu, Yao Xiao, Bing Liu, Qiuji Wu, Zhiyong Song, Lin‐Lin Bu   +11 more
wiley   +1 more source

Myeloid immunosuppression and immune checkpoints in the tumor microenvironment

Cellular & Molecular Immunology, 2019
Kyohei Nakamura, M. Smyth
semanticscholar   +1 more source

Immunosuppression and cancer. [PDF]

, 1973
Penn, I, Starzl, TE
core  

Novel Quaternary Ammonium Salt‐Linked STING Agonist Antibody‐Drug Conjugate: Synergistic Activation of Tumor Immunity with Mitigated Off‐Target Toxicity

Advanced Science, EarlyView.
Novel quaternary ammonium salt‐linked STING agonist ADC demonstrates high potency, stability, enhanced solubility, and reduced off‐target toxicity, potently activating the STING pathway in the tumor microenvironment through the synergistic action of the Fab and Fc regions of antibodies (activity switch‐on) while exhibiting ≈20 fold lower activity in ...
Yu Long, Borui Tang, Fei Xie, Lianqi Liu, Yangyihua Zhou, Jingwen Dong, Jianfeng Wang, Cuicui Sun, Yuting Wang, Ruoqi Li, Na Zhang, Liping Li, Longlong Luo, Junhai Xiao, Wu Zhong, Dian Xiao, Hongbin Deng, Xinbo Zhou   +17 more
wiley   +1 more source

A Rare Case of Parvovirus Infection Causing Pure Red Cell Aplasia in a Kidney-Pancreas Transplant Recipient. [PDF]

Nephrology (Carlton)
Perry O, Ellis R, Dang S, John GT, Hendry S, Ng MSY.   +5 more
europepmc   +1 more source

Lack of Effect of Immunosuppression on Scrapie Infection in Mice

, 1971
M. Worthington, R.G. Clark
openalex   +1 more source

Immunosuppression by hydroxystilbamidine isethionate, a lysosome-stabilizing, anti-proteolytic, antifungal drug [PDF]

, 1975
James D. Folds, G Orlando, J K Spitznagel   +2 more
openalex   +1 more source

PARP Inhibitor Upregulates PD-L1 Expression and Enhances Cancer-Associated Immunosuppression

Clinical Cancer Research, 2017
Shiping Jiao, W. Xia, H. Yamaguchi, Yongkun Wei, Mei-Kuang Chen, Jung-Mao Hsu, J. Hsu, Wen-Hsuan Yu, Yi Du, Heng-Huan Lee, Chia‐Wei Li, C. Chou, Seung-Oe Lim, Shih-Shin Chang, J. Litton, B. Arun, G. Hortobagyi, M. Hung   +17 more
semanticscholar   +1 more source

Targeted Dual‐Responsive Liposomes Co‐Deliver Jolkinolide B and Ce6 to Synergistically Enhance the Photodynamic/Immunotherapy Efficacy in Gastric Cancer through the PANoptosis Pathway

Advanced Science, EarlyView.
Schematic model of CJP–TiN liposomes for gastric cancer (GC) treatment. Internalizing RGD peptide (iRGD) targets tumor cells, while Chlorin e6 (Ce6) generates reactive oxygen species (ROS). Jolkinolide B (JB) activates the PANoptosis pathway via caspase‐8, enhancing GC cell death and immune response, transforming “cold tumors” into “hot tumors” by ...
Chenhui Ma, Lei Gao, Kewei Song, Baohong Gu, Bofang Wang, Yang Yu, Xueyan Wang, Xuemei Li, Jike Hu, Weigao Pu, Yunpeng Wang, Na Wang, Dedai Lu, Zhijian Han, Hao Chen   +14 more
wiley   +1 more source