Results 201 to 210 of about 392,479 (342)

Immunosuppression with cis -Platinum (II) Diammino-dichloride: Effect on Antibody Plaque-Forming Spleen Cells [PDF]

, 1971
Amanullah Khan, Joseph M. Hill
openalex   +1 more source

Core Fucosylation Represses SMURF1‐Dependent Degradation of CD47 to Promote Tumor Immune Evasion

Advanced Science, EarlyView.
FUT8‐mediated core fucosylation of CD47 at N111 blocks SMURF1 binding and reduces CD47 ubiquitination and degradation. Blocking N111 glycosylation reduces CD47 expression and promotes macrophage phagocytosis of tumor cells. Furthermore, ablating CD47 core fucosylation boosts CD103+ dendritic cells (DCs) infiltration, increases natural killer (NK) cell ...
Yuting Cao, Siyuan Chai, Mingyang Li, Xiaoming Chen, Jiating Hu, Bingyi Lin, Liming Wu, Wen Yi, Qiang Zhu   +8 more
wiley   +1 more source

Drug-Induced Partial Immunosuppression for Preclinical Human Tumor Xenograft Models. [PDF]

Cancers (Basel)
Gorbushin AK, Luzan NA, Kakhanova VD, Koshmanova AA, Grek DS, Voronkovskii II, Farniev VM, Melikhova ES, Lukyanenko KA, Veprintsev DV, Morozov EV, Dymova MA, Kuligina EV, Pryakhin EA, Richter VA, Styazhkina EV, Lipetskaya EA, Garkusha TA, Zamay TN, Kolovskaya OS, Narodov AA, Kumeiko VV, Berezovski MV, Kichkailo AS.   +23 more
europepmc   +1 more source

Immunosuppression-Associated Pathology [PDF]

Pathobiology, 2013
openaire   +2 more sources

Neural Substrates for Behaviorally Conditioned Immunosuppression in the Rat [PDF]

, 2005
Gustavo Pacheco‐López, Maj‐Britt Niemi, Wei Kou, Margarete Härting, Joachim Fandrey, Manfred Schedlowski   +5 more
openalex   +1 more source

Conversion of Transplanted Mature Hepatocytes into Afp+ Reprogrammed Cells for Liver Regeneration After Injury

Advanced Science, EarlyView.
Donor‐derived tdTomato+ mature hepatocytes were FACS‐isolated and transplanted into Fah−/− host mice. During regeneration, these cells convert into proliferative, unipotent Afp+ rHeps. Their plasticity is governed by a PPARγ/AFP‐dependent metabolic switch, segregating into pro‐proliferative Afplow and pro‐survival Afphigh subpopulations.
Ting Fang, Chao Yang, Hua Qiu, Yuan Du, Xicheng Wang, Yuting Li, Mingyang Xu, Changcheng Liu, Xiuhua Li, Na Guo, Jun Shi, Wencheng Zhang, Zhiying He   +12 more
wiley   +1 more source

Supplementary Figure 9 from Antagonizing Integrin β3 Increases Immunosuppression in Cancer

, 2023
Xinming Su, Alison K. Esser, Sarah R. Amend, Jingyu Xiang, Yalin Xu, Michael H. Ross, Gregory C. Fox, Takayuki Kobayashi, Veronica Steri, Kirsten Roomp, Francesca Fontana, Michelle A. Hurchla, Brett L. Knolhoff, Melissa A. Meyer, Elizabeth A. Morgan, Julia C. Tomasson, Joshua S. Novack, Wei Zou, Roberta Faccio, Deborah V. Novack, Stephen Robinson, Steven L. Teitelbaum, David G. DeNardo, Jochen G. Schneider, Katherine N. Weilbaecher   +24 more
openalex   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Immunosuppressive Therapy in Pediatric Kidney Transplantation: Evolution, Current Practices, and Future Directions. [PDF]

Biomedicines
Al Riyami MS, Al Gaithi B, Al Kalbani N, Al Saidi S.   +3 more
europepmc   +1 more source

Magnetoelectric Nanotherapy Achieves Complete Tumor Ablation and Prolonged Survival in Pancreatic Cancer Murine Models

Advanced Science, EarlyView.
Magnetoelectric nanoparticles (MENPs) serve as externally controlled, MRI‐activated theranostic agents for targeted cancer therapy by inducing electric field‐based ablation in solid tumors. MENPs enable simultaneous precise tumor ablation and MRI signal modulation, allowing real‐time treatment monitoring and prediction of therapeutic outcomes with no ...
John Michael Bryant, Max Shotbolt, Emmanuel Stimphil, Victoria Andre, Elric Zhang, Veronica Estrella, Kazim Husain, Joseph Weygand, Doug Marchion, Alex Sebastian Lopez, Dominique Abrahams, Shawnus Chen, Mostafa Abdel‐Mottaleb, Skye Conlan, Ibrahim Oraiqat, Vaseem Khatri, Jose Alejandro Guevara, Shari Pilon‐Thomas, Gage Redler, Kujtim Latifi, Natarajan Raghunand, Kosj Yamoah, Sarah Hoffe, James Costello, Jessica M. Frakes, Ping Liang, Robert A. Gatenby, Mokenge Malafa, Sakhrat Khizroev   +28 more
wiley   +1 more source