Results 21 to 30 of about 453,253 (341)

Intestinal transplantation in children under FK 506 immunosuppression [PDF]

open access: yes, 1993
Intestinal transplantation, solitary (n = 3) or in combination with the liver (n = 7), was performed in 10 pediatric patients with intestinal failure. The liver was only replaced if there was liver failure and portal hypertension.
Adrian Casavilla   +26 more
core   +1 more source

Early herpes and TTV DNAemia in septic shock patients: a pilot study

open access: yesIntensive Care Medicine Experimental, 2019
Background Septic shock patients exhibit an increased incidence of viral reactivation. Precise timing of such reactivation—as an early marker of immune suppression, or as a consequence of the later—is not known precisely.
François Mallet   +18 more
doaj   +1 more source

Generic immunosuppressants

open access: yesPediatric Nephrology, 2017
Immunosuppressive drugs for solid organ transplantation are critical dose drugs with a narrow therapeutic index. Many of the most commonly used innovator drugs are off patent and have been replicated by generic counterparts, often at substantial cost-savings to the patient.
Mara Medeiros   +4 more
openaire   +5 more sources

Understanding sepsis-induced immunosuppression and organ dysfunctions: from immunosuppression to immunotherapy

open access: yesExploration of Immunology, 2022
Sepsis is a life-threatening condition caused by dysregulated host immune response to infection, leading to persistent inflammation followed by immunosuppression.
Dablu Lal Gupta   +4 more
doaj   +1 more source

Reversibility of lymphomas and lymphoproliferative lesions developing under cyclosporin-steroid therapy [PDF]

open access: yes, 1984
Post-transplant lymphomas or other lymphoproliferative lesions, which were usually associated with Epstein-Barr virus infections, developed in 8, 4, 3, and 2 recipients, respectively, of cadaveric kidney, liver, heart, and heart-lung homografts ...
Atchison, RW   +12 more
core   +1 more source

Endogenous Retroviruses Transcriptional Modulation After Severe Infection, Trauma and Burn

open access: yesFrontiers in Immunology, 2019
Although human endogenous retroviruses (HERVs) expression is a growing subject of interest, no study focused before on specific endogenous retroviruses loci activation in severely injured patients.
Olivier Tabone   +18 more
doaj   +1 more source

T cell response against SARS-CoV-2 persists after one year in patients surviving severe COVID-19

open access: yesEBioMedicine, 2022
Summary: Background: In critically ill COVID-19 patients, the initial response to SARS-CoV-2 infection is characterized by major immune dysfunctions.
Fabienne Venet   +24 more
doaj   +1 more source

Immunosuppressive Medications [PDF]

open access: yesClinical Journal of the American Society of Nephrology, 2016
Immunosuppressive agents are commonly used in the nephrologist's practice in the treatment of autoimmune and immune-mediated diseases and transplantation, and they are investigational in the treatment of AKI and ESRD. Drug development has been rapid over the past decades as mechanisms of the immune response have been better defined both by serendipity (
openaire   +2 more sources

Effect of Maintaining Immunosuppression After Kidney Allograft Failure on Mortality and Retransplantation

open access: yesTransplantation Direct, 2023
Background. Few studies have addressed immunosuppression management after allograft failure (AF). Immunosuppression withdrawal to minimize complications must be balanced with the risk of sensitization and potentially reduced retransplantation.
Suryanarayanan Balakrishnan, MD   +6 more
doaj   +1 more source

The Mechanism of Mori Folium and Eucommiae Cortex against Cyclophosphamide-Induced Immunosuppression Integrating Network Pharmacology, Molecular Docking, Molecular Dynamics Simulations, and Experimental Validation

open access: yesMetabolites, 2023
It has been reported that Mori Folium (MF) and Eucommiae Cortex (EC) exhibit pharmacological effects in the treatment of immunosuppression. However, the mechanism of MF and EC against immunosuppression remains unclear.
Jinde Liu   +6 more
doaj   +1 more source

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