Results 21 to 30 of about 514,735 (343)

Use of convalescent plasma in COVID‐19 patients with immunosuppression

Transfusion, 2021
In the absence of effective countermeasures, human convalescent plasma has been widely used to treat severe acute respiratory syndrome coronavirus 2, the causative agent of novel coronavirus disease 19 (COVID‐19), including among patients with innate or ...
Jonathon W. Senefeld, S. Klassen, S. Ford, K. Senese, C. Wiggins, B. Bostrom, M. Thompson, S. Baker, W. Nicholson, Patrick W. Johnson, R. Carter, J. P. Henderson, W. Hartman, L. Pirofski, R. Wright, D. Fairweather, K. A. Bruno, N. Paneth, A. Casadevall, M. Joyner   +19 more
semanticscholar   +1 more source

Pancreas and islet cell transplantation [PDF]

, 2002
Currently, for the patient with type 1 diabetes, a definitive treatment without resorting to the use of exogenous insulin can be achieved only with pancreas or islet cell transplantation.
A.N. Balamurugan, Alexander, Allen, Amos, Barber, Barrou, Bartlett, Björk, Bonner-Weir, Brekke, Calne, Calne, Cameron, Cheung, Chow, Corry, Diem, Diem, DiLandro, Fontes, Giannoukakis, Giannoukakis, Gibson, Gliedman, Grey, Groth, Groth, Gu, Gupta, Harris, Hayek, Henry, Ilieva, Kelly, Kemp, Kendall, Kendall, Keymeulen, Kirk, Koike, Koike, Lacy, Lafferty, Lakey, Lillehei, London, Massimo Trucco, Mazariegos, Mintz, Murray, Najarian, Nghiem, Paraskevas, Petruzzo, Piehlmeier, Pipeleers-Marichal, Posselt, Prevost, Rajotte, Ramiya, Ramos, Ricordi, Rita Bottino, Robertson, Shapiro, Simeonovic, Solders, Sollinger, Sollinger, Sollinger, Soria, Ssobolew, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Stone, Stratta, Stratta, Sutherland, Suzuki, Tchervenivanov, Terasaki, Thomas E. Starzl, Tyden, Tzakis, Yasunami   +94 more
core   +1 more source

Reversibility of lymphomas and lymphoproliferative lesions developing under cyclosporin-steroid therapy [PDF]

, 1984
Post-transplant lymphomas or other lymphoproliferative lesions, which were usually associated with Epstein-Barr virus infections, developed in 8, 4, 3, and 2 recipients, respectively, of cadaveric kidney, liver, heart, and heart-lung homografts ...
Atchison, RW, Bahnson, HT, Griffith, BP, Hakala, TR, Hardesty, RL, Ho, M, Iwatsuki, S, Jaffe, R, Nalesnik, MA, Porter, KA, Rosenthal, JT, Shaw, BW, Starzl, TE   +12 more
core   +1 more source

Intestinal transplantation in children under FK 506 immunosuppression [PDF]

, 1993
Intestinal transplantation, solitary (n = 3) or in combination with the liver (n = 7), was performed in 10 pediatric patients with intestinal failure. The liver was only replaced if there was liver failure and portal hypertension.
Adrian Casavilla, Andreas G. Tzakis, Anthony J. Demetris, Bakr Nour, David H. Van Thiel, Eduardo Yunis, Goulet, Grant, Iwaki, Jorge Reyes, Kareem Abu-Elmagd, Murase, Murase, Rick Selby, Samuel Kocoshis, Satoru Todo, Schraut, Shaffer, Starzl, Starzl, Starzl, Thomas E. Starzl, Todo, Todo, Tzakis, Tzakis, Zhong   +26 more
core   +1 more source

The Dark Side of Fibroblasts: Cancer-Associated Fibroblasts as Mediators of Immunosuppression in the Tumor Microenvironment

Frontiers in Immunology, 2019
Cancer-associated fibroblasts (CAFs) are prominent components of the microenvironment in most types of solid tumors, and were shown to facilitate cancer progression by supporting tumor cell growth, extracellular matrix remodeling, promoting angiogenesis,
Lea Monteran, Neta Erez
semanticscholar   +1 more source

Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections

JCI Insight, 2020
COVID-19–associated morbidity and mortality have been attributed to a pathologic host response. Two divergent hypotheses have been proposed: hyperinflammatory cytokine storm; and failure of host protective immunity that results in unrestrained viral ...
Kenneth E. Remy, M. Mazer, David A. Striker, A. Ellebedy, A. Walton, J. Unsinger, T. Blood, P. Mudd, Daehan J. Yi, Daniel Mannion, D. Osborne, R. S. Martin, Nitin J. Anand, James P. Bosanquet, J. Blood, A. Drewry, C. Caldwell, Isaiah R. Turnbull, S. Brakenridge, Lyle L. Moldwawer, R. Hotchkiss   +20 more
semanticscholar   +1 more source

Prevalence of Immunosuppression Among US Adults.

Journal of the American Medical Association (JAMA)
This analysis presents population prevalence estimates of immunosuppression among US adults using data from the 2021 National Health Interview Survey.
Melissa L Martinson, J. Lapham
semanticscholar   +1 more source

FK506 IN PEDIATRIC KIDNEY-TRANSPLANTATION - PRIMARY AND RESCUE EXPERIENCE [PDF]

, 1995
Between December 14, 1989, and December 17, 1993,43 patients undergoing kidney transplantation alone at the Children’s Hospital of Pittsburgh received FK506 as the primary immunosuppressive agent. The mean recipient age was 10.2 ± 4.8 years (range 0.7–17.
ELLIS, D, GILBOA, N, HAKALA, TR, HOPP, L, IRISH, W, JORDAN, ML, MCCAULEY, J, MITCHELL, S, SCANTLEBURY, VP, SHAPIRO, R, SIMMONS, RL, STARZL, TE, TZAKIS, AG, VIVAS, C   +13 more
core   +1 more source

Immunosuppression mediated by myeloid-derived suppressor cells (MDSCs) during tumour progression

British Journal of Cancer, 2018
Under steady-state conditions, bone marrow-derived immature myeloid cells (IMC) differentiate into granulocytes, macrophages and dendritic cells (DCs). This differentiation is impaired under chronic inflammatory conditions, which are typical for tumour ...
Christopher Groth, Xiaoying Hu, Rebekka Weber, Viktor Fleming, P. Altevogt, J. Utikal, V. Umansky   +6 more
semanticscholar   +1 more source

Immunosuppression in Glioblastoma: Current Understanding and Therapeutic Implications

Frontiers in Oncology, 2021
Glioblastoma (GBM) is the most common primary brain tumor in adults an carries and carries a terrible prognosis. The current regiment of surgical resection, radiation, and chemotherapy has remained largely unchanged in recent years as new therapeutic ...
B. Himes, P. Geiger, K. Ayasoufi, A. Bhargav, Desmond A. Brown, I. Parney   +5 more
semanticscholar   +1 more source