Results 41 to 50 of about 521,863 (391)

The Mechanism of Mori Folium and Eucommiae Cortex against Cyclophosphamide-Induced Immunosuppression Integrating Network Pharmacology, Molecular Docking, Molecular Dynamics Simulations, and Experimental Validation

Metabolites, 2023
It has been reported that Mori Folium (MF) and Eucommiae Cortex (EC) exhibit pharmacological effects in the treatment of immunosuppression. However, the mechanism of MF and EC against immunosuppression remains unclear.
Jinde Liu, Qiao Rong, Chunxiao Zhang, Ali Tariq, Lin Li, Yongning Wu, Feifei Sun   +6 more
doaj   +1 more source

Generic immunosuppressants

Pediatric Nephrology, 2017
Immunosuppressive drugs for solid organ transplantation are critical dose drugs with a narrow therapeutic index. Many of the most commonly used innovator drugs are off patent and have been replicated by generic counterparts, often at substantial cost-savings to the patient.
Mara Medeiros, Julia Lumini, Noah Stern, Gilberto Castañeda-Hernández, Guido Filler   +4 more
openaire   +5 more sources

Endogenous Retroviruses Transcriptional Modulation After Severe Infection, Trauma and Burn

Frontiers in Immunology, 2019
Although human endogenous retroviruses (HERVs) expression is a growing subject of interest, no study focused before on specific endogenous retroviruses loci activation in severely injured patients.
Olivier Tabone, Marine Mommert, Marine Mommert, Camille Jourdan, Elisabeth Cerrato, Matthieu Legrand, Alain Lepape, Bernard Allaouchiche, Bernard Allaouchiche, Thomas Rimmelé, Alexandre Pachot, Guillaume Monneret, Guillaume Monneret, Fabienne Venet, Fabienne Venet, François Mallet, François Mallet, Julien Textoris, Julien Textoris   +18 more
doaj   +1 more source

Effect of Maintaining Immunosuppression After Kidney Allograft Failure on Mortality and Retransplantation

Transplantation Direct, 2023
Background. Few studies have addressed immunosuppression management after allograft failure (AF). Immunosuppression withdrawal to minimize complications must be balanced with the risk of sensitization and potentially reduced retransplantation.
Suryanarayanan Balakrishnan, MD, Byron Smith, PhD, MS, Andrew Bentall, MD, Aleksandra Kukla, MD, Massini Merzkani, MD, Mark Stegall, MD, Carrie Schinstock, MD   +6 more
doaj   +1 more source

Longitudinal assessment of IFN-I activity and immune profile in critically ill COVID-19 patients with acute respiratory distress syndrome

Critical Care, 2021
Background Since the onset of the pandemic, only few studies focused on longitudinal immune monitoring in critically ill COVID-19 patients with acute respiratory distress syndrome (ARDS) whereas their hospital stay may last for several weeks ...
Fabienne Venet, Martin Cour, Thomas Rimmelé, Sebastien Viel, Hodane Yonis, Remy Coudereau, Camille Amaz, Paul Abraham, Céline Monard, Jean-Sebastien Casalegno, Karen Brengel-Pesce, Anne-Claire Lukaszewicz, Laurent Argaud, Guillaume Monneret, the RICO study group   +14 more
doaj   +1 more source

Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections

JCI Insight, 2020
COVID-19–associated morbidity and mortality have been attributed to a pathologic host response. Two divergent hypotheses have been proposed: hyperinflammatory cytokine storm; and failure of host protective immunity that results in unrestrained viral ...
Kenneth E. Remy, M. Mazer, David A. Striker, A. Ellebedy, A. Walton, J. Unsinger, T. Blood, P. Mudd, Daehan J. Yi, Daniel Mannion, D. Osborne, R. S. Martin, Nitin J. Anand, James P. Bosanquet, J. Blood, A. Drewry, C. Caldwell, Isaiah R. Turnbull, S. Brakenridge, Lyle L. Moldwawer, R. Hotchkiss   +20 more
semanticscholar   +1 more source

Reversibility of lymphomas and lymphoproliferative lesions developing under cyclosporin-steroid therapy [PDF]

, 1984
Post-transplant lymphomas or other lymphoproliferative lesions, which were usually associated with Epstein-Barr virus infections, developed in 8, 4, 3, and 2 recipients, respectively, of cadaveric kidney, liver, heart, and heart-lung homografts ...
Atchison, RW, Bahnson, HT, Griffith, BP, Hakala, TR, Hardesty, RL, Ho, M, Iwatsuki, S, Jaffe, R, Nalesnik, MA, Porter, KA, Rosenthal, JT, Shaw, BW, Starzl, TE   +12 more
core   +1 more source

Induction immunosuppression and post-transplant diabetes mellitus: a propensity-matched cohort study

Frontiers in Endocrinology, 2023
IntroductionPost-transplant diabetes mellitus (PTDM) is a common complication among cardiac transplant recipients, causing diabetes-related complications and death.
Suruchi K. Gupta, Suruchi K. Gupta, Suruchi K. Gupta, Elizabeth Mostofsky, Shweta R. Motiwala, Shweta R. Motiwala, Ali Hage, Ali Hage, Murray A. Mittleman, Murray A. Mittleman, Murray A. Mittleman   +10 more
doaj   +1 more source

The Dark Side of Fibroblasts: Cancer-Associated Fibroblasts as Mediators of Immunosuppression in the Tumor Microenvironment

Frontiers in Immunology, 2019
Cancer-associated fibroblasts (CAFs) are prominent components of the microenvironment in most types of solid tumors, and were shown to facilitate cancer progression by supporting tumor cell growth, extracellular matrix remodeling, promoting angiogenesis,
Lea Monteran, Neta Erez
semanticscholar   +1 more source

Immunosuppression for liver transplantation in HCV-infected patients: Mechanism-based principles [PDF]

, 2005
We retrospectively analyzed 42 hepatitis C virus (HCV)-infected patients who underwent cadaveric liver transplantation under two strategies of immunosuppression: (1) daily tacrolimus (TAC) throughout and an initial cycle of high-dose prednisone (PRED ...
Bass, DC, Demetris, AJ, Eghtesad, B, Flynn, B, Fung, JJ, Gray, EA, Marcos, A, Murase, N, Ness, R, Shakil, O, Starzl, TE   +10 more
core   +1 more source