Results 31 to 40 of about 4,619,877 (335)

Medical Complications of Lung Transplantation

Journal of Chest Surgery, 2022
Lung transplantation (LT) is now considered as an effective treatment option for end-stage lung diseases that improves the short and long-term survival rates and quality of life.
Moo Suk Park
doaj   +1 more source

Clinical valuables related to resolution of complete or advanced atrioventricular block after steroid therapy in patients with cardiac sarcoidosis

Journal of Arrhythmia, 2021
Background Prediction of atrioventricular block (AVB) resolution after steroid therapy in patients with cardiac sarcoidosis (CS) is difficult. Methods We identified 24 patients with CS and complete or advanced AVB receiving steroid therapy.
Takeru Nabeta, Masahiko Hara, Takashi Naruke, Kenji Maemura, Takumi Oki, Mayu Yazaki, Teppei Fujita, Yuki Ikeda, Shunsuke Ishii, Toshimi Koitabashi, Junya Ako   +10 more
doaj   +1 more source

Macrophages as tools and targets in cancer therapy

Nature reviews. Drug discovery, 2022
Tumour-associated macrophages are an essential component of the tumour microenvironment and have a role in the orchestration of angiogenesis, extracellular matrix remodelling, cancer cell proliferation, metastasis and immunosuppression, as well as in ...
A. Mantovani, P. Allavena, F. Marchesi, C. Garlanda   +3 more
semanticscholar   +1 more source

Transplant Coordinators' Perceived Impact of Availability of Multiple Generic Immunosuppression Therapies on Patients, Workload, and Posttransplant Maintenance Therapy

Journal of Transplantation, 2013
Background. No studies have evaluated the impact of multiple generic immunosuppression medications on transplant coordinators (TCs) and patients. Methods.
K. Parker, E. A. Zagadailov, A. S. Bruno, A. M. Wiland   +3 more
doaj   +1 more source

Fecal microbiota transplant overcomes resistance to anti–PD-1 therapy in melanoma patients

Science, 2021
New fecal microbiota for cancer patients The composition of the gut microbiome influences the response of cancer patients to immunotherapies. Baruch et al. and Davar et al.
D. Davar, A. Dzutsev, J. McCulloch, R. Rodrigues, Joe-Marc Chauvin, Robert M. Morrison, R. Deblasio, Carmine Menna, Quanquan Ding, Ornella Pagliano, Bochra Zidi, Shuowen Zhang, J. Badger, Marie Vetizou, A. Cole, M. R. Fernandes, Stephanie Prescott, R. G. Costa, A. Balaji, A. Morgun, I. Vujkovic-Cvijin, Hong Wang, Amir A. Borhani, M. Schwartz, Howard M. Dubner, Scarlett J. Ernst, Amy Rose, Y. Najjar, Y. Belkaid, J. Kirkwood, G. Trinchieri, H. Zarour   +31 more
semanticscholar   +1 more source

Dialysis Dependency at Discharge in De Novo ANCA Associated Renal Limited Vasculitis: Should We Avoid Further Immunosuppression?

Revista Portuguesa de Nefrologia e Hipertensão, 2022
Introduction: ANCA associated vasculitis commonly affects the kidneys. The intense inflammatory damage disrupts the glomerular architecture. Induction immunosuppressive therapy is responsible for a large part of the morbidity and mortality of these ...
Rui Filipe Nogueira, Nuno Afonso Oliveira, Margarida Gaudêncio, Ana Belmira, Rui Alves   +4 more
doaj   +1 more source

Analysis of early use of everolimus with low-dose calcineurin inhibitors in kidney transplant recipient

Вестник трансплантологии и искусственных органов, 2019
Aim: to evaluate the efficacy and safety of early use of everolimus in combination with a reduced dose of calcineurin inhibitors (CNI) after kidney transplantation and define approaches to the selection and management of patients on everolimus-based ...
I. G. Kim, N. A. Tomilina, I. V. Ostrovskaya, I. A. Skryabina, N. D. Fedorova   +4 more
doaj   +1 more source

Lactate-Lactylation Hands between Metabolic Reprogramming and Immunosuppression

International Journal of Molecular Sciences, 2022
Immune evasion and metabolic reprogramming are two fundamental hallmarks of cancer. Interestingly, lactate closely links them together. However, lactate has long been recognized as a metabolic waste product.
Lihua Chen, Lixiang Huang, Yu Gu, W. Cang, P. Sun, Yang Xiang   +5 more
semanticscholar   +1 more source

Monoclonal antibody‐mediated immunosuppression enables long‐term survival of transplanted human neural stem cells in mouse brain

Clinical and Translational Medicine, 2022
Background As the field of stem cell therapy advances, it is important to develop reliable methods to overcome host immune responses in animal models. This ensures survival of transplanted human stem cell grafts and enables predictive efficacy testing ...
Lisa M. McGinley, Kevin S. Chen, Shayna N. Mason, Diana M. Rigan, Jacquelin F. Kwentus, John M. Hayes, Emily D. Glass, Evan L. Reynolds, Geoffrey G. Murphy, Eva L. Feldman   +9 more
doaj   +1 more source

Effect of Immunosuppression on the Immunogenicity of mRNA Vaccines to SARS-CoV-2

Annals of Internal Medicine, 2021
Evidence suggests that immunogenicity to mRNA-based SARS-CoV-2 vaccination in immunosuppressed patients may be reduced. This study assessed the response to 2 doses of mRNA-based SARS-CoV-2 vaccine among 133 participants with underlying chronic ...
P. Deepak, Wooseob Kim, Michael A. Paley, Monica M. Yang, A. Carvidi, Emanuel Demissie, Alia A. El-Qunni, Alem Haile, Katherine Huang, Baylee Kinnett, Mariel J. Liebeskind, Zhuoming Liu, L. McMorrow, D. Páez, Niti Pawar, D. Perantie, Rebecca E. Schriefer, Shannon E. Sides, Mahima Thapa, M. Gergely, Suha Abushamma, Sewuese Akuse, Michael K Klebert, Lynne M. Mitchell, D. Nix, J. Graf, K. Taylor, S. Chahin, M. Ciorba, P. Katz, M. Matloubian, Jane A. O’Halloran, R. Presti, Gregory F. Wu, S. Whelan, W. Buchser, L. Gensler, Mary C. Nakamura, A. Ellebedy, A. H. Kim   +39 more
semanticscholar   +1 more source