Results 41 to 50 of about 213,546 (300)

Changes in glucose metabolism among recipients with diabetes 1 year after kidney transplant: a multicenter 1-year prospective study

open access: yesFrontiers in Endocrinology, 2023
BackgroundDiabetes mellitus is a common and crucial metabolic complication in kidney transplantation. It is necessary to analyze the course of glucose metabolism in patients who already have diabetes after receiving a transplant.
Jun Bae Bang   +14 more
doaj   +1 more source

Medical Complications of Lung Transplantation

open access: yesJournal of Chest Surgery, 2022
Lung transplantation (LT) is now considered as an effective treatment option for end-stage lung diseases that improves the short and long-term survival rates and quality of life.
Moo Suk Park
doaj   +1 more source

Individualized immunosuppression in transplant patients: potential role of pharmacogenetics.

open access: yes, 2012
The immunosuppressive drugs used to prevent the rejection of transplanted organs have a narrow therapeutic index. Under treatment results in episodes of rejection leading to either damage or loss of the organ. Over immunosuppression increases the risk of
MacPhee IA   +3 more
core   +1 more source

A prospective randomised, open-labeled, trial comparing sirolimus-containing versus mTOR-inhibitor-free immunosuppression in patients undergoing liver transplantation for hepatocellular carcinoma

open access: yes, 2010
Background: The potential anti-cancer effects of mammalian target of rapamycin (mTOR) inhibitors are being intensively studied. To date, however, few randomised clinical trials (RCT) have been performed to demonstrate anti-neoplastic effects in the pure ...
Pinna, Antonio D.   +392 more
core   +1 more source

Helminths and immunological tolerance [PDF]

open access: yes, 2014
Current immunosuppression regimens for solid-organ transplantation have shown disappointing efficacy in the prevention of chronic allograft rejection and carry unacceptable risks including toxicity, neoplasia, and life-threatening infection.
McSorley, Henry J.   +11 more
core   +1 more source

The Role of Immunosuppression for Recurrent Cholangiocellular Carcinoma after Liver Transplantation [PDF]

open access: yes, 2022
SIMPLE SUMMARY: Oncological follow-up after liver transplantation for cholangiocellular carcinoma must consider the risk of recurrence. Immunosuppressive medication with so-called mTOR inhibitors seems to have a tumor-suppressive effect, as improved ...
Öllinger, Robert   +25 more
core   +1 more source

Analysis of early use of everolimus with low-dose calcineurin inhibitors in kidney transplant recipient

open access: yesВестник трансплантологии и искусственных органов, 2019
Aim: to evaluate the efficacy and safety of early use of everolimus in combination with a reduced dose of calcineurin inhibitors (CNI) after kidney transplantation and define approaches to the selection and management of patients on everolimus-based ...
I. G. Kim   +4 more
doaj   +1 more source

Development and validation of multivariable prediction models of serological response to SARS-CoV-2 vaccination in kidney transplant recipients

open access: yesFrontiers in Immunology, 2022
Repeated vaccination against SARS-CoV-2 increases serological response in kidney transplant recipients (KTR) with high interindividual variability. No decision support tool exists to predict SARS-CoV-2 vaccination response to third or fourth vaccination ...
Bilgin Osmanodja   +17 more
doaj   +1 more source

Neo-Adjuvant Chemotherapy Reduces, and Surgery Increases Immunosuppression in First-Line Treatment for Ovarian Cancer

open access: yes, 2021
UNLABELLED: In monotherapy, immunotherapy has a poor success rate in ovarian cancer. Upgrading to a successful combinatorial immunotherapy treatment implies knowledge of the immune changes that are induced by chemotherapy and surgery.
Jolien Ceusters   +24 more
core   +1 more source

Successful treatment with tofacitinib for anti-melanoma differentiation-associated gene 5 antibody-positive juvenile dermatomyositis: case reports and review of the literature

open access: yesImmunological Medicine
Although the clinical efficacy of tofacitinib has been reported in adult patients with anti-melanoma differentiation-associated gene 5 (MDA5) antibody-positive (Ab+) dermatomyositis, data on its use in refractory juvenile dermatomyositis (JDM) are scarce.
Susumu Yamazaki   +13 more
doaj   +1 more source

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