Mesenchymal stem cell-mediated T cell immunosuppression [PDF]
, 2017 Besides being a pool forstromal cells and connective tissues, the mesenchymal stem cells (MSCs) as well exert a potent immunosuppression against almost all types of immune cells, particularly T cells.
Al-Graittee, Satar Jabbar Rahi +2 more
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FIRST EXPERIENCE OF APPLICATION OF ASSIST CIRCULATION DEVICE USING BIVENTRICULAR TYPE «EXCOR»
Вестник хирургии имени И.И. Грекова, 2018 The frequency of use of assist blood device as the «bridge» to the heart transplantation increased in last years. An assessment of results of first 7 implantations of assist circulation device using biventricular type «Excor» was made.
M. L. Gordeev +12 more
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Frontiers in Medicine, 2022 Patients with leprosy may experience a chronic and severe type II leprosy reaction (ENL) erythema nodosum leprosum that may not respond to thalidomide and systemic immunosuppressants or may even cause serious adverse events. We here present four patients
Ana Flávia Moura Mendes +4 more
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Combinatorial functions of two chimeric antibodies directed to human CD4 and one directed to the a-chain of the human interleukin-2 receptor [PDF]
, 1992 The general feasibility of chimerization of monoclonal antibodies (mAbs) has already been shown for a large number of them. In order to evaluate in vitro parameters relevant to immunosuppressive therapy, we have chimerized and synthesized two anti-CD4 ...
Schwirzke, Marina +10 more
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Fulminant Myocarditis in Patients With Autoimmune Disease That Requires Extracorporeal Membrane Oxygenation Support [PDF]
Texas Heart Institute JournalMyocarditis is a potentially life-threatening inflammatory disease of the myocardium, often resulting from infectious and immune-mediated responses. Clinical presentation in severe cases often results in a devastating illness requiring extracorporeal ...
Filip Depta, MD, PhD +5 more
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Immunosuppressive therapy in polymyositis [PDF]
Journal of Neurology, Neurosurgery & Psychiatry, 1971 Immunosuppressive drugs were given to seven patients with polymyositis. The in-vitro activity of peripheral blood lymphocytes had previously been studied in five of these patients with findings suggestive of disturbed immunological processes. Some improvement occurred in five cases, but only in two was the improvement marked and sustained.
S, Currie, J N, Walton
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Cerebral Amyloid Angiopathy- Related Inflammation: A Case Report and Literature Review
Journal of the Korean Society of Radiology, 2023 Cerebral amyloid angiopathy-related inflammation (CAA-RI) is an encephalopathy caused by inflammation of β-amyloid peptide deposition in cerebrovascular vessels.
Chanjin Park, Eun Sun Choi, Eunhee Kim
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Cellular Therapies for Immunosuppression [PDF]
, 2012 Almost all current therapeutic approaches to inhibit destructive immune responses in autoimmunity are based on antigen non-specific agents, such as cyclosporine A, which systemically suppress the function of virtually all immune effector cells.
Cools, Nathalie +2 more
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A Promising New Therapeutic Strategy to Improve Mortality Outcomes in Patients with Moderate to Severe Paraquat Poisoning [PDF]
Asia Pacific Journal of Medical ToxicologyBackground: Paraquat ingestion is associated with multi-organ failure and high mortality. The lack of management guidelines and an appropriate antidote is concerning.
Bennett Philip +4 more
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Genetic Therapy Approaches for Ornithine Transcarbamylase Deficiency
, 2023 Ornithine transcarbamylase deficiency (OTCD) is the most common urea cycle disorder with high unmet needs, as current dietary and medical treatments may not be sufficient to prevent hyperammonemic episodes, which can cause death or neurological sequelae.
Berna Seker Yilmaz, Paul Gissen
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