Results 101 to 110 of about 7,988 (196)

Elderberries: A Source of Ribosome-Inactivating Proteins with Lectin Activity

open access: yesMolecules, 2015
Sambucus (Adoxaceae) species have been used for both food and medicine purposes. Among these, Sambucus nigra L. (black elder), Sambucus ebulus L. (dwarf elder), and Sambucus sieboldiana L. are the most relevant species studied.
Jesús Tejero   +7 more
doaj   +1 more source

Humanized CD7 nanobody-based immunotoxins exhibit promising anti-T-cell acute lymphoblastic leukemia potential

open access: yesInternational Journal of Nanomedicine, 2017
Yuan Yu,1–3 Jialu Li,1–3 Xuejun Zhu,4 Xiaowen Tang,2,5 Yangyi Bao,6 Xiang Sun,6 Yuhui Huang,1,2 Fang Tian,4 Xiaomei Liu,1,2 Lin Yang1–3 1The Cyrus Tang Hematology Center, 2Collaborative Innovation Center of Hematology, Soochow ...
Yu Y   +9 more
doaj  

Construction of a Single Chain Variable Fragment Against Mcf-7 Breast Cancer Cells [PDF]

open access: yes, 2008
Recombinant antibody cloning and phage display technologies can be employed to produce and isolate single-chain antibodies (scFv) specifically against antigen of interest.
Ahmad, Zuhaida Asra
core  

Immunoconjugates as an Efficient Platform for Drug Delivery: A Resurgence of Natural Products in Targeted Antitumor Therapy

open access: yesPharmaceuticals
The present review provides a detailed and comprehensive discussion on antibody–drug conjugates (ADCs) as an evolving new modality in the current therapeutic landscape of malignant diseases.
Rositsa Mihaylova   +3 more
doaj   +1 more source

A novel bispecific immunotoxin delivered by human bone marrow-derived mesenchymal stem cells to target blood vessels and vasculogenic mimicry of malignant gliomas

open access: yesDrug Design, Development and Therapy, 2015
Yonghong Zhang,1,2 Xinlin Sun,1 Min Huang,1 Yiquan Ke,1 Jihui Wang,1 Xiao Liu1 1National Key Clinic Specialty, Neurosurgery Institute of Guangdong Province, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Department of ...
Zhang Y   +5 more
doaj  

Disulfonated tetraphenyl chlorin (TPCS2a)–induced photochemical internalisation of bleomycin in patients with solid malignancies: A first-in-man phase I dose escalation clinical trial [PDF]

open access: yes, 2016
BACKGROUND: Photochemical internalisation, a novel minimally invasive treatment, has shown promising preclinical results in enhancing and site-directing the effect of anticancer drugs by illumination, which initiates localised chemotherapy release.
Berg, K   +10 more
core  

Potentiation of therapeutic immune responses against malignancies with monoclonal antibodies [PDF]

open access: yes, 2003
Immunotherapeutic monoclonal antibodies (mAbs) can be defined as those that exert their functions by tampering with immune system cell molecules, causing an enhancement of antitumor immune responses. Some of these antibodies are agonistic ligands for
Alfaro, C. (Carlos)   +9 more
core  

Lectinas vegetales: utilización en histoquímica y terapia antitumoral [PDF]

open access: yes, 2016
Numerosas plantas expresan en su composición una o más lectinas o bien proteínas con un dominio lectina, permitiendo a éstas seleccionar y unirse a determinadas estructuras.
Velasco Martín, Felipe
core  

immunotoxin

open access: yes
Citation: 'immunotoxin' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13326 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

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