Results 101 to 110 of about 7,656 (201)

Reversal of gastrointestinal carcinoma-induced immunosuppression and induction of antitumoural immunity by a combination of cyclophosphamide and gene transfer of IL-12 [PDF]

, 2011
Immunotherapy-based strategies for gastrointestinal carcinomas (GIC) have been exploited so far, but these approaches have to face strong mechanisms of immune escape induced by tumours.
Alaniz, Almand, Appay, Barajas, Bell, Beyer, Bluestone, Brodsky, Bronte, Caruso, Catalina Atorrasagasti, Clark, Colombo, Colvin, Croci, Curiel, Dieckmann, Elkord, Ferlay, Flavia Piccioni, Gabrilovich, Gabrilovich, Ghiringhelli, Ghiringhelli, Gomez, Guillermo Mazzolini, Haigh, Huang, Jaime A. Espinoza, Jorge B. Aquino, Juan Bayo, Kerkar, Ko, Larmonier, Laura Alaniz, Leonard, Lorenz, Malvicini, Manuel Gidekel, Mariana Garcia, Mariana Ingolotti, Mariana Malvicini, Matar, Mazzolini, Mazzolini, Mazzolini, Medina-Echeverz, Melero, Nestle, O. Graciela Scharovsky, Onishi, Ormandy, Pablo Matar, Proietti, Putzer, Rabinovich, Sakaguchi, Sangro, Shapira, Spaapen, Suzuki, Takahashi, Tang, Thornton, Trinchieri, Vignali, Yokoyama, Zou, Zou, Zwirner   +69 more
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Ricin: An Ancient Story for a Timeless Plant Toxin

Toxins, 2019
The castor plant (Ricinus communis L.) has been known since time immemorial in traditional medicine in the pharmacopeia of Mediterranean and eastern ancient cultures. Moreover, it is still used in folk medicine worldwide.
Letizia Polito, Massimo Bortolotti, Maria Giulia Battelli, Giulia Calafato, Andrea Bolognesi   +4 more
doaj   +1 more source

Elderberries: A Source of Ribosome-Inactivating Proteins with Lectin Activity

Molecules, 2015
Sambucus (Adoxaceae) species have been used for both food and medicine purposes. Among these, Sambucus nigra L. (black elder), Sambucus ebulus L. (dwarf elder), and Sambucus sieboldiana L. are the most relevant species studied.
Jesús Tejero, Pilar Jiménez, Emiliano J. Quinto, Damián Cordoba-Diaz, Manuel Garrosa, Manuel Cordoba-Diaz, Manuel J. Gayoso, Tomás Girbés   +7 more
doaj   +1 more source

Humanized CD7 nanobody-based immunotoxins exhibit promising anti-T-cell acute lymphoblastic leukemia potential

International Journal of Nanomedicine, 2017
Yuan Yu,1–3 Jialu Li,1–3 Xuejun Zhu,4 Xiaowen Tang,2,5 Yangyi Bao,6 Xiang Sun,6 Yuhui Huang,1,2 Fang Tian,4 Xiaomei Liu,1,2 Lin Yang1–3 1The Cyrus Tang Hematology Center, 2Collaborative Innovation Center of Hematology, Soochow ...
Yu Y, Li J, Zhu X, Tang X, Bao Y, Sun X, Huang Y, Tian F, Liu X, Yang L   +9 more
doaj  

Immunoconjugates as an Efficient Platform for Drug Delivery: A Resurgence of Natural Products in Targeted Antitumor Therapy

Pharmaceuticals
The present review provides a detailed and comprehensive discussion on antibody–drug conjugates (ADCs) as an evolving new modality in the current therapeutic landscape of malignant diseases.
Rositsa Mihaylova, Denitsa Momekova, Viktoria Elincheva, Georgi Momekov   +3 more
doaj   +1 more source

Construction of a Single Chain Variable Fragment Against Mcf-7 Breast Cancer Cells [PDF]

, 2008
Recombinant antibody cloning and phage display technologies can be employed to produce and isolate single-chain antibodies (scFv) specifically against antigen of interest.
Ahmad, Zuhaida Asra
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A novel bispecific immunotoxin delivered by human bone marrow-derived mesenchymal stem cells to target blood vessels and vasculogenic mimicry of malignant gliomas

Drug Design, Development and Therapy, 2015
Yonghong Zhang,1,2 Xinlin Sun,1 Min Huang,1 Yiquan Ke,1 Jihui Wang,1 Xiao Liu1 1National Key Clinic Specialty, Neurosurgery Institute of Guangdong Province, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Department of ...
Zhang Y, Sun X, Huang M, Ke Y, Wang J, Liu X   +5 more
doaj  

Article III: Some Building Blocks [PDF]

, 1998
Ye
Pearson, Graham S.
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Disulfonated tetraphenyl chlorin (TPCS2a)–induced photochemical internalisation of bleomycin in patients with solid malignancies: A first-in-man phase I dose escalation clinical trial [PDF]

, 2016
BACKGROUND: Photochemical internalisation, a novel minimally invasive treatment, has shown promising preclinical results in enhancing and site-directing the effect of anticancer drugs by illumination, which initiates localised chemotherapy release.
Berg, K, carnell, D, Forster, M, Hamdoon, Z, Hamoudi, R, hogset, A, Hopper, C, Jerjes, W, Mosse, C, Simeon, C, Sultan, A   +10 more
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Potentiation of therapeutic immune responses against malignancies with monoclonal antibodies [PDF]

, 2003
Immunotherapeutic monoclonal antibodies (mAbs) can be defined as those that exert their functions by tampering with immune system cell molecules, causing an enhancement of antitumor immune responses. Some of these antibodies are agonistic ligands for
Alfaro, C. (Carlos), Arina, A. (Ainhoa), Bendandi, M. (Maurizio), Lopez-Diaz-de-Cerio, A. (Ascensión), Mazzolini, G. (Guillermo), Melero, I. (Ignacio), Murillo, O. (Oihana), Palencia, B. (Belén), Prieto, J. (Jesús), Tirapu, I. (Íñigo)   +9 more
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