Results 81 to 90 of about 3,943 (171)

Humanized CD7 nanobody-based immunotoxins exhibit promising anti-T-cell acute lymphoblastic leukemia potential

International Journal of Nanomedicine, 2017
Yuan Yu,1–3 Jialu Li,1–3 Xuejun Zhu,4 Xiaowen Tang,2,5 Yangyi Bao,6 Xiang Sun,6 Yuhui Huang,1,2 Fang Tian,4 Xiaomei Liu,1,2 Lin Yang1–3 1The Cyrus Tang Hematology Center, 2Collaborative Innovation Center of Hematology, Soochow ...
Yu Y, Li J, Zhu X, Tang X, Bao Y, Sun X, Huang Y, Tian F, Liu X, Yang L   +9 more
doaj  

Augmentation of Saporin-Based Immunotoxins for Human Leukaemia and Lymphoma Cells by Triterpenoid Saponins: The Modifying Effects of Small Molecule Pharmacological Agents

Toxins, 2019
Triterpenoid saponins from Saponinum album (SA) significantly augment the cytotoxicity of saporin-based immunotoxins but the mechanism of augmentation is not fully understood.
Wendy S. Smith, David A. Johnston, Suzanne E. Holmes, Harrison J. Wensley, Sopsamorn U. Flavell, David J. Flavell   +5 more
doaj   +1 more source

Immunoconjugates as an Efficient Platform for Drug Delivery: A Resurgence of Natural Products in Targeted Antitumor Therapy

Pharmaceuticals
The present review provides a detailed and comprehensive discussion on antibody–drug conjugates (ADCs) as an evolving new modality in the current therapeutic landscape of malignant diseases.
Rositsa Mihaylova, Denitsa Momekova, Viktoria Elincheva, Georgi Momekov   +3 more
doaj   +1 more source

A novel bispecific immunotoxin delivered by human bone marrow-derived mesenchymal stem cells to target blood vessels and vasculogenic mimicry of malignant gliomas

Drug Design, Development and Therapy, 2015
Yonghong Zhang,1,2 Xinlin Sun,1 Min Huang,1 Yiquan Ke,1 Jihui Wang,1 Xiao Liu1 1National Key Clinic Specialty, Neurosurgery Institute of Guangdong Province, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Department of ...
Zhang Y, Sun X, Huang M, Ke Y, Wang J, Liu X   +5 more
doaj  

immunotoxin

Citation: 'immunotoxin' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13326 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Designing a Novel Immunotoxin against Prostate Cancer based on PE40 Toxin: An <i>In silico</i> Approach. [PDF]

Avicenna J Med Biotechnol
Azdoo S, Taheri-Anganeh M, Ahmadi K, Ghadimi Moghadam A, Movahedpour A, Jamshidi A.   +5 more
europepmc   +1 more source

Lethal toxin-equipped effector cells for the potential treatment of cancer. [PDF]

Proc Natl Acad Sci U S A
Pearlman AH, Mog BJ, Hwang MS, Rincon-Torroella J, DiNapoli SR, Paul S, Douglass J, Hsiue EH, Glavaris SA, Pardoll DM, Papadopoulos N, Kinzler KW, Bettegowda C, Zhou S, Vogelstein B, Konig MF.   +15 more
europepmc   +1 more source

GPA33-Targeted Trimeric Immunotoxin Exhibits Enhanced Antitumor Activity in Human Colorectal Cancer Xenografts. [PDF]

Int J Mol Sci
Ruiz-de-la-Herrán J, Narbona J, Gordo RG, Sanz L, Lacadena J.   +4 more
europepmc   +1 more source

Advances in Targeted Toxin Therapy for Malignant Gliomas: A Narrative Review. [PDF]

Toxins (Basel)
Polavarapu H, Hall WA.
europepmc   +1 more source

A proimmunotoxin nanodrug targeting AIDS-associated non-Hodgkin lymphoma. [PDF]

J Control Release
Chen S, Qi T, Peng H, Kimura E, Zhang X, Kranz E, Cao Z, Wang Z, Chen W, Ancheta LR, Lappi DA, Chiou PY, Lu Y, Daniels-Wells TR, Penichet ML, Wen J.   +15 more
europepmc   +1 more source