Results 101 to 110 of about 7,748 (215)

Ricin: An Ancient Story for a Timeless Plant Toxin

open access: yesToxins, 2019
The castor plant (Ricinus communis L.) has been known since time immemorial in traditional medicine in the pharmacopeia of Mediterranean and eastern ancient cultures. Moreover, it is still used in folk medicine worldwide.
Letizia Polito   +4 more
doaj   +1 more source

Synthesis and biodistribution of immunoconjugates of a human IgM and polymeric drug carriers [PDF]

open access: yes, 1992
The synthesis and purification of radiolabelled immunoconjugates, composed of a human IgM monoclonal antibody directed against an intracellular tumour-associated antigen and either poly (alpha-L-glutamic acid) (PGA) or poly[N5-(2-hydroxyethyl)-L ...
Anderson, James M.   +9 more
core   +2 more sources

Elderberries: A Source of Ribosome-Inactivating Proteins with Lectin Activity

open access: yesMolecules, 2015
Sambucus (Adoxaceae) species have been used for both food and medicine purposes. Among these, Sambucus nigra L. (black elder), Sambucus ebulus L. (dwarf elder), and Sambucus sieboldiana L. are the most relevant species studied.
Jesús Tejero   +7 more
doaj   +1 more source

Estimation of Enzymatic Activities of Different Species of Mushrooms [PDF]

open access: yes, 2011
Mushrooms are widely spread saprophytic macro-organisms, belong to class fungi growing on dead organic matter of vegetative origin. They can utilize almost all agricultural wastes as their substrates for their growth and metabolism.
Chandra Mishra , Rahul
core  

Humanized CD7 nanobody-based immunotoxins exhibit promising anti-T-cell acute lymphoblastic leukemia potential

open access: yesInternational Journal of Nanomedicine, 2017
Yuan Yu,1–3 Jialu Li,1–3 Xuejun Zhu,4 Xiaowen Tang,2,5 Yangyi Bao,6 Xiang Sun,6 Yuhui Huang,1,2 Fang Tian,4 Xiaomei Liu,1,2 Lin Yang1–3 1The Cyrus Tang Hematology Center, 2Collaborative Innovation Center of Hematology, Soochow ...
Yu Y   +9 more
doaj  

Construction of a Single Chain Variable Fragment Against Mcf-7 Breast Cancer Cells [PDF]

open access: yes, 2008
Recombinant antibody cloning and phage display technologies can be employed to produce and isolate single-chain antibodies (scFv) specifically against antigen of interest.
Ahmad, Zuhaida Asra
core  

Immunoconjugates as an Efficient Platform for Drug Delivery: A Resurgence of Natural Products in Targeted Antitumor Therapy

open access: yesPharmaceuticals
The present review provides a detailed and comprehensive discussion on antibody–drug conjugates (ADCs) as an evolving new modality in the current therapeutic landscape of malignant diseases.
Rositsa Mihaylova   +3 more
doaj   +1 more source

A novel bispecific immunotoxin delivered by human bone marrow-derived mesenchymal stem cells to target blood vessels and vasculogenic mimicry of malignant gliomas

open access: yesDrug Design, Development and Therapy, 2015
Yonghong Zhang,1,2 Xinlin Sun,1 Min Huang,1 Yiquan Ke,1 Jihui Wang,1 Xiao Liu1 1National Key Clinic Specialty, Neurosurgery Institute of Guangdong Province, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Department of ...
Zhang Y   +5 more
doaj  

A case of accidental Ricin poisoning [PDF]

open access: yes, 2004
A case report of accidental, mild ricin poisoning by ingestion of ten Castor beans by a 70 year old man. The clinical presentation is followed by a discussion about the toxicity of ricin, its use and misuse and the contrast between the toxicity of pure ...
Cachia, Mario J., Despott, Edward
core  

Disulfonated tetraphenyl chlorin (TPCS2a)–induced photochemical internalisation of bleomycin in patients with solid malignancies: A first-in-man phase I dose escalation clinical trial [PDF]

open access: yes, 2016
BACKGROUND: Photochemical internalisation, a novel minimally invasive treatment, has shown promising preclinical results in enhancing and site-directing the effect of anticancer drugs by illumination, which initiates localised chemotherapy release.
Berg, K   +10 more
core  

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