Results 91 to 100 of about 7,748 (215)

Bifenthrin Under Scrutiny: Revisiting Toxicological Evidence Amid Regulatory Gaps

Journal of Applied Toxicology, Volume 46, Issue 1, Page 61-77, January 2026.
ABSTRACT Despite growing health concerns, bifenthrin (BF) remains widely used for controlling agricultural and residential pests. However, different perspectives on its toxicological profile and regulatory framework warrant a revisit and update on BF regulation towards a robust risk‐safety assessment.
Caroline V. L. Moreira, John Ogbu I, Kadja L. C. Monteiro, Thiago M. de Aquino, Edeildo F. da Silva‐Júnior, Alberto S. S. Filho, Hamilton B. Napolitano, Christianah A. Elusiyan, Renê O. do Couto, Elson A. Costa, James O. Fajemiroye   +10 more
wiley   +1 more source

Inclusion of a Furin Cleavage Site Enhances Antitumor Efficacy against Colorectal Cancer Cells of Ribotoxin α-Sarcin- or RNase T1-Based Immunotoxins

Toxins, 2019
Immunotoxins are chimeric molecules that combine the specificity of an antibody to recognize and bind tumor antigens with the potency of the enzymatic activity of a toxin, thus, promoting the death of target cells.
Javier Ruiz-de-la-Herrán, Jaime Tomé-Amat, Rodrigo Lázaro-Gorines, José G. Gavilanes, Javier Lacadena   +4 more
doaj   +1 more source

Ricin as a Biothreat Agent: From Molecular Mechanisms to Clinical Toxicology, Forensic Aspects, and Risk Mitigation

BioMed Research International, Volume 2026, Issue 1, 2026.
Ricin, a potent ribosome‐inactivating protein derived from the seeds of Ricinus communis L., represents a significant threat in the context of biological warfare and terrorism due to its high toxicity, ease of extraction, and lack of a specific antidote.
Miroslav Pohanka, Poorani Gurumallesh Prabu   +1 more
wiley   +1 more source

Mycoflora and Aflatoxin Contamination of Some Foodstuffs [PDF]

, 2013
Analysis was made of the mycoflora and aflatoxin contamination of Rice (Oryza sativa), Beans (Phaseolus vulgaris), Corn (Zea mays), and Groundnut (Arachis hypogaea) sold in four different markets in Sango-Ota, Ogun state, Nigeria.
Olarewaju, S.A., Oranusi, S. U.
core  

SS1P Immunotoxin Induces Markers of Immunogenic Cell Death and Enhances the Effect of the CTLA-4 Blockade in AE17M Mouse Mesothelioma Tumors

Toxins, 2018
SS1P is an anti-mesothelin immunotoxin composed of a targeting antibody fragment genetically fused to a truncated fragment of Pseudomonas exotoxin A. Delayed responses reported in mesothelioma patients receiving SS1P suggest that anti-tumor immunity is ...
Yasmin Leshem, Emily M. King, Ronit Mazor, Yoram Reiter, Ira Pastan   +4 more
doaj   +1 more source

Botulinum neurotoxin type C protease induces apoptosis in differentiated human neuroblastoma cells [PDF]

, 2016
Neuroblastomas constitute a major cause of cancer-related deaths in young children. In recent years, a number of translation-inhibiting enzymes have been evaluated for killing neuroblastoma cells. Here we investigated the potential vulnerability of human
Binz, T., Davletov, B., Leese, C., Rust, A.   +3 more
core   +1 more source

Article III: Some Building Blocks [PDF]

, 1998
Ye
Pearson, Graham S.
core  

Second line therapy in malignant pleural mesothelioma: a systematic review [PDF]

, 2015
After the implementation of standard first line chemotherapy with platinum and antifolates in pleural mesothelioma, patients are confronted with a need for second line treatment at relapse or progression.
Baas, Paul, Buikhuisen, Wieneke A, Hiddingab, Birgitta I, Van Meerbeeck, Jan   +3 more
core   +2 more sources

Efficacy of Anti-Cancer Immune Responses Elicited Using Tumor-Targeted IL-2 Cytokine and Its Derivatives in Combined Preclinical Therapies

Vaccines
Effective cancer therapies must address the tumor microenvironment (TME), a complex network of tumor cells and stromal components, including endothelial, immune, and mesenchymal cells. Durable outcomes require targeting both tumor cells and the TME while
Sahar Balkhi, Giorgia Bilato, Andrea De Lerma Barbaro, Paola Orecchia, Alessandro Poggi, Lorenzo Mortara   +5 more
doaj   +1 more source

T-Cell Receptor-Like Antibodies: Targeting the Intracellular Proteome Therapeutic Potential and Clinical Applications

Antibodies, 2013
Major histocompatibility complex (MHC) class I molecules are key in the immune response against malignant cells by shaping the T-cell repertoire and presenting peptides from endogenous antigens to CD8+ cytotoxic T cells.
Maya Cohen, Yoram Reiter
doaj   +1 more source