Advanced Functional Materials, EarlyView.An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu +14 more
wiley +1 more source
Prevalence of diabetes mellitus and impaired glucose tolerance in a rural community of Angola
Diabetology & Metabolic Syndrome, 2010 Background To determine the prevalence of diabetes mellitus (DM) and impaired glucose tolerance (IGT) in a rural community (Bengo) of Angola. Methods A random sample of 421 subjects aged 30 to 69 years (30% men and 70% women) was selected from three ...
Evaristo-Neto Antonio D +2 more
doaj +1 more source
Recurrent reactive hypoglycemia due to clozapine‐induced glucose intolerance: A case report
PCN Reports, 2023 Background Although diabetes is one of the most common side effects of clozapine, a medication for the treatment of schizophrenia, to the best of our knowledge no study exists on clozapine‐induced glucose intolerance or hypoglycemia in patients with ...
Fumihiko Kawai +8 more
doaj +1 more source
Neuronal SIRT1 Regulates Metabolic and Reproductive Function and the Response to Caloric Restriction. [PDF]
, 2019 Sirt1 is an NAD-dependent, class III deacetylase that functions as a cellular energy sensor. In addition to its well-characterized effects in peripheral tissues, emerging evidence suggests that neuronal Sirt1 activity plays a role in the central ...
Choi, Irene +5 more
core
Lifestyle intervention in individuals with impaired glucose regulation affects Caveolin-1 expression and DNA methylation [PDF]
, 2020 © 2020, © 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. Aims: We investigated whether a lifestyle intervention could influence expression and DNA methylation of diabetes-related genes in patients with impaired ...
Adam, S. +9 more
core +1 more source
Advanced Functional Materials, EarlyView.A modular biosynthetic PVA–gelatin hydrogel crosslinked via visible‐light thiol‐ene chemistry is engineered as a coating for neural electrodes. Optimizing matrix composition and mechanical properties enables the hydrogel to support astrocytic populations that guide neural differentiation and functional maturation.
Martina Genta +4 more
wiley +1 more source
Demographic and metabolic characteristics of individuals with progressive glucose tolerance
Brazilian Journal of Medical and Biological Research, 2009 We evaluated changes in glucose tolerance of 17 progressors and 62 non-progressors for 9 years to improve our understanding of the pathogenesis of type 2 diabetes mellitus. Changes in anthropometric measurements and responses to an oral glucose tolerance
A.L. Mendes +3 more
doaj
Journal of Lipid Research, 2010 Cholesterol synthesis is upregulated and absorption downregulated in insulin resistance and in type 2 dia-betes. We investigated whether alterations in cholesterol metabolism are observed across the glucose tolerance status, from normoglycemia through ...
Helena Gylling +6 more
doaj +1 more source
The influence of different glucose tolerance on QTc interval: a population-based study
BMC Cardiovascular Disorders, 2023 Background Corrected QT (QTc) interval has been reported to be associated with type 2 diabetes. This study aimed to explore the relationship between different glucose tolerance and QTc intervals among middle-aged and older Chinese individuals. Methods We
Ning Lin +8 more
doaj +1 more source
Improved Aerobic Capacity and Adipokine Profile Together with Weight Loss Improve Glycemic Control without Changes in Skeletal Muscle GLUT-4 Gene Expression in Middle-Aged Subjects with Impaired Glucose Tolerance [PDF]
, 2022 Mika Venojärvi +4 more
openalex +1 more source