Results 51 to 60 of about 630,465 (319)

O-12 CHARACTERIZATION AND UTILIZATION OF HCV-POSITIVE DONORS IN ARGENTINA

Annals of Hepatology, 2023
Introduction and Objectives: Increased utilization of hepatitis C virus (HCV)-positive organ donors has been endorsed as one of several ways to combat organ shortages. However, HCV-positive donors remain poorly characterized. This study aimed to evaluate
Manuel Mendizabal, Margarita Anders, Ariel Antik, Federico Piñero, Gabriela Hidalgo, Daniela Hansen Krogh, Viviana Tagliafichi, Marcelo Silva, Liliana Bisigniano   +8 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Angiotensin-converting enzyme insertion/deletion polymorphism does not influence the restenosis rate after coronary stent implantation [PDF]

, 2002
Background. Experimental studies have shown an activation of the angiotensin-converting enzyme (ACE) system as a response to endothelial injury. Recent publications have elucidated the hypothesis that the ACE gene polymorphism may influence the level of ...
Hausmann, Dirk, Koschyk, Dietmar H., Grip, Lars, Ferrari, Markus, de Jaegere, Peter, Rieber, Johannes, Figulla, Hans R., Mudra, Harald, Schächinger, Volker, Rothman, Martin, Voudris, Vassilis   +10 more
core   +1 more source

Impact of Al-ion implantation on the formation of deep defects in n-type 4H-SiC

, 2022
S.66-69In this work, deep defects in an aluminum implanted 4H-SiC n-type epitaxy are discussed in dependence on following influencing factors: concentration of implanted aluminum, implantation energy, implantation at 500°C and at room temperature, as ...
Rüb, Michael, Frey, Lothar, Mitlehner, Heinz, Bauer, A.J., Rommel, Mathias, Hauck, Martin, Weiße, Julietta, Häublein, Volker, Erlekampf, Jürgen, Csato, Constantin, Akhmadaliev, Shavkat, Krieger, Michael, Erlbacher, Tobias   +12 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

110GHz fT Silicon Bipolar Transistors Implemented using Fluorine Implantation for Boron Diffusion Suppression

, 2006
This paper investigates how fluorine implantation can be used to suppress boron diffusion in the base of a double polysilicon silicon bipolar transistor and hence deliver a record fT of 110 GHz.
Ashburn, Peter, El Mubarek, H.A.W., Bonar, J.M., Ashburn, P., Fiore, L., Kham, M. N., Petralia, R., El Mubarek, H. A W, Ward, P., Messina, A., Kham, M.N., Alemanni, C., Bonar, J. M.   +12 more
core   +1 more source

Association of antimüllerian hormone with polycystic ovarian syndrome phenotypes and pregnancy outcomes of in vitro fertilization cycles with fresh embryo transfer

BMC Pregnancy and Childbirth, 2022
Objective The current study was undertaken to investigate the relationship between antimüllerian hormone (AMH) and polycystic ovarian syndrome (PCOS) phenotypes and to determine whether AMH is associated with pregnancy outcomes in infertile women ...
Su Liu, Ling Hong, Meilan Mo, Shan Xiao, Xuejin Wang, Xinfeng Fan, Sainan Zhang, Lianghui Diao, Yong Zeng   +8 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Ion implantation into nanoparticulate functional layers

, 2009
S.537-540Layers of silicon nanoparticles with resistivity down to 10 mΩcm are demonstrated using chemical and thermal treatment as well as ion implantation. Morphology and crystallinity of the layers are characterized using AFM and XRD.
Jank, M.P.M., Walther, S., Ebbers, A., Ryssel, H.   +3 more
core   +1 more source

Simulation von BF3-Plasmaionenimplantation: Implantation, Amorphisierung und Diffusion

, 2022
S.237-240In the race for highly doped ultra-shallow junctions (USJs) in complementary metal oxide semi-conductor (CMOS) technologies, plasma immersion ion implantation (PIII) is a promising alternative to traditional beamline implantation.
Cristiano, F., Essa, Z., Quillec, M., Torregrosa, F., Taleb, N., Qiu, Y., Boulenc, P., Spiegel, Y., Tavernier, C., Mortet, V., Burenkov, A., Hackenberg, M., Bedel-Pereira, E.   +12 more
core   +1 more source