Results 61 to 70 of about 2,679,990 (305)

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +6 more
wiley   +1 more source

Exploring the syndemic interaction between social, environmental and structural contexts of HIV infection in peri-mining areas in South Africa: a qualitative study

BMJ Open
Objective To explore the syndemic interaction between social, environmental, and structural contexts and HIV infection in peri-mining areas in South Africa.Design Mixed qualitative methods consisting of in-depth interviews (IDIs) and focus group ...
Salome Charalambous, Lucy Chimoyi, Pretty Ndini, Matthew Oladimeji, Nieser Seatlholo, Kudzai Mawokomatanda, Geoffrey Setswe   +6 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Patient experiences of tuberculosis treatment deferral after a trace Xpert Ultra result: a prospective cohort study

Infectious Diseases of Poverty
Background A “trace” result from the Xpert Ultra molecular tuberculosis test indicates Mycobacterium tuberculosis DNA detection but may not always signify tuberculosis disease.
Caitlin Visek, James Mukiibi, Mariam Nantale, Annet Nalutaaya, Patrick Biché, Joowhan Sung, Francis Kayondo, Joab Akampurira, Michael Mukiibi, Rogers Kiyonga, Achilles Katamba, Emily A. Kendall   +11 more
doaj   +1 more source

Report on Aarhus Implementation - Ireland [PDF]

, 2022
This Report identifies issues with the implementation of the Aarhus Convention in Ireland. The Aarhus Convention UNECE 1998 is an international convention providing for a set of “environmental democracy” rights.
Doran, Peter, Brennan, Ciara, Hough, Alison   +2 more
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Predicting suicide death among veterans after psychiatric hospitalization using transformer based models with social determinants and NLP

Scientific Reports
Predictions of suicide death of patients discharged from psychiatric hospitals (PDPH) can guide intervention efforts including intensive post-discharge case management programs, designed to reduce suicide risk among high-risk patients. This study aims to
Zhichao Yang, Avijit Mitra, Wen Hu, Dan Berlowitz, Hong Yu   +4 more
doaj   +1 more source

Is distance associated with tuberculosis treatment outcomes? A retrospective cohort study in Kampala, Uganda

BMC Infectious Diseases, 2020
Background Challenges accessing nearby health facilities may be a barrier to initiating and completing tuberculosis (TB) treatment. We aimed to evaluate whether distance from residence to health facility chosen for treatment is associated with TB ...
Katherine O. Robsky, Seamus Hughes, Alex Kityamuwesi, Emily A. Kendall, Peter James Kitonsa, David W. Dowdy, Achilles Katamba   +6 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source