KRT6A Restricts Influenza A Virus Replication by Inhibiting the Nuclear Import and Assembly of Viral Ribonucleoprotein Complex. [PDF]
Chang Y +9 more
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Oncometabolite fumarate facilitates PD-L1 expression and immune evasion in clear cell renal cell carcinoma. [PDF]
Gao Y +8 more
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The NLS3 Motif in TPX2 Regulates Spindle Architecture in Xenopus Egg Extracts. [PDF]
Pena GE +4 more
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Nucleus-translocated glucokinase functions as a protein kinase to phosphorylate TAZ and promote tumour growth. [PDF]
Zhao G +16 more
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RNMT-dependent RNA cap methylation in health and disease. [PDF]
Mills JG, Hepburn LA, Cowling VH.
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Importin α transports CaMKIV to the nucleus without utilizing importin β
openaire
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Importins: Diverse roles in male fertility
Seminars in Cell & Developmental Biology, 2022Regulated nucleocytoplasmic transport is central to the changes in gene expression that underpin cellular development and homeostasis, including in the testis, and proteins in the importin family are the predominant facilitators of cargo transport through the nuclear envelope.
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Structure of importin-β bound to the IBB domain of importin-α
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The importin β/importin 7 heterodimer is a functional nuclear import receptor for histone H1 [PDF]
Import of proteins into the nucleus proceeds through nuclear pore complexes and is largely mediated by nuclear transport receptors of the importin beta family that use direct RanGTP-binding to regulate the interaction with their cargoes. We investigated nuclear import of the linker histone H1 and found that two receptors, importin beta (Impbeta) and ...
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