Results 1 to 10 of about 75,707 (295)

An Unconventional NLS is Critical for the Nuclear Import of the Influenza A Virus Nucleoprotein and Ribonucleoprotein

Traffic, 2005
Adolfo Garcia-Sastre, Peter Palese
exaly  

Prostaglandin D2 induces nuclear import of the sex-determining factor SOX9 via its cAMP-PKA phosphorylation

EMBO Journal, 2005
Serge Nef, Cecile Notarnicola, Philippe Berta   +2 more
exaly  

Evidence for the nuclear import of histones H3.1 and H4 as monomers

EMBO Journal, 2018
Juan Ramon Hernández-Fernaud, Andrew Bowman   +1 more
exaly  

Nuclear Import of HIV-1 [PDF]

Viruses, 2021
The delivery of the HIV-1 genome into the nucleus is an indispensable step in retroviral infection of non-dividing cells, but the mechanism of HIV-1 nuclear import has been a longstanding debate due to controversial experimental evidence. It was commonly
Qi Shen, Chunxiang Wu, Christian Freniere, Therese N. Tripler, Yong Xiong   +4 more
doaj   +4 more sources

tRNAs promote nuclear import of HIV-1 intracellular reverse transcription complexes.

PLoS Biology, 2006
Infection of non-dividing cells is a biological property of HIV-1 crucial for virus transmission and AIDS pathogenesis. This property depends on nuclear import of the intracellular reverse transcription and pre-integration complexes (RTCs/PICs).
Lyubov Zaitseva, Richard Myers, Ariberto Fassati   +2 more
doaj   +3 more sources

Nuclear Import of Yeast Proteasomes [PDF]

Cells, 2015
Proteasomes are highly conserved protease complexes responsible for the degradation of aberrant and short-lived proteins. In highly proliferating yeast and mammalian cells, proteasomes are predominantly nuclear.
Julianne Burcoglu, Liang Zhao, Cordula Enenkel   +2 more
doaj   +6 more sources

Dynamics and regulation of nuclear import and nuclear movements of HIV-1 complexes. [PDF]

PLoS Pathogens, 2017
The dynamics and regulation of HIV-1 nuclear import and its intranuclear movements after import have not been studied. To elucidate these essential HIV-1 post-entry events, we labeled viral complexes with two fluorescently tagged virion-incorporated ...
Ryan C Burdick, Krista A Delviks-Frankenberry, Jianbo Chen, Sanath K Janaka, Jaya Sastri, Wei-Shau Hu, Vinay K Pathak   +6 more
doaj   +4 more sources

Direct visualization of HIV-1 core nuclear import and its interplay with the nuclear pore [PDF]

EMBO Reports
Direct visualization of HIV-1 nuclear import through the nuclear pore complex (NPC) presents a technical challenge due to the rarity of this process.
Zhen Hou, Stanley Fronik, Yao Shen, Long Chen, Christopher Thompson, Sarah Neumann, Peijun Zhang   +6 more
doaj   +3 more sources

Inhibition of nuclear import suppresses androgen receptor action and overcomes resistance in prostate cancer [PDF]

BMC Cancer
Background Androgen deprivation and androgen receptor (AR) antagonists are essential treatments for prostate cancers in the clinic. However, after an initially effective response, most tumors become resistant to androgen deprivation therapies. Resistance
Xuan Wang, Xin Xu, Shengyun Fang, Xiaolei Shi, Yili Yang   +4 more
doaj   +2 more sources

Dissecting the Nuclear Import of the Ribosomal Protein Rps2 (uS5)

Biomolecules, 2023
The ribosome is assembled in a complex process mainly taking place in the nucleus. Consequently, newly synthesized ribosomal proteins have to travel from the cytoplasm into the nucleus, where they are incorporated into nascent ribosomal subunits. In this
Andreas Steiner, Sébastien Favre, Maximilian Mack, Annika Hausharter, Benjamin Pillet, Jutta Hafner, Valentin Mitterer, Dieter Kressler, Brigitte Pertschy, Ingrid Zierler   +9 more
doaj   +2 more sources