Types of nuclear localization signals and mechanisms of protein import into the nucleus [PDF]
Cell Communication and Signaling, 2021 Nuclear localization signals (NLS) are generally short peptides that act as a signal fragment that mediates the transport of proteins from the cytoplasm into the nucleus.
Juane Lu +6 more
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Identification of Nuclear Localization Signals in the ORF2 Protein of Porcine Circovirus Type 3 [PDF]
Viruses, 2019 Porcine circovirus type 3 (PCV3) contains two major open reading frames (ORFs) and the ORF2 gene encodes the major structural capsid protein. In this study, nuclear localization of ORF2 was demonstrated by fluorescence observation and subcellular ...
Chunxiao Mou +3 more
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Nuclear Delivery of Nanoparticle-Based Drug Delivery Systems by Nuclear Localization Signals [PDF]
Cells, 2023 Nanomedicine 2.0 refers to the next generation of nanotechnology-based medical therapies and diagnostic tools. This field focuses on the development of more sophisticated and precise nanoparticles (NPs) for targeted drug delivery, imaging, and sensing ...
Yuhan Nie, Guo Fu, Yuxin Leng
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Two nuclear localization signals regulate intracellular localization of the duck enteritis virus UL13 protein [PDF]
Poultry Science, 2021 Duck enteritis virus (DEV) multifunctional tegument protein UL13 is predicted to be a conserved herpesvirus protein kinase; however, little is known about its subcellular localization signal.
Linjiang Yang +23 more
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Nuclear Localization Signals for Optimization of Genetically Encoded Tools in Neurons [PDF]
Frontiers in Cell and Developmental Biology, 2022 Nuclear transport in neurons differs from that in non-neuronal cells. Here we developed a non-opsin optogenetic tool (OT) for the nuclear export of a protein of interest induced by near-infrared (NIR) light.
Maksim M. Karasev +4 more
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Multiple types of nuclear localization signals in Entamoeba histolytica [PDF]
Biochemistry and Biophysics ReportsEntamoeba histolytica is a protozoan parasite that belongs to the Amoebozoa supergroup whose study related to the nucleocytoplasmic transport of proteins through the nucleus is poorly studied.
Israel Canela-Pérez +4 more
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Data from comprehensive analysis of nuclear localization signals [PDF]
Data in Brief, 2016 This article describes data related to a research article titled “Comprehensive analysis of the dynamic structure of nuclear localization signals” by Yamagishi et al. [1]. In this article, we provide the data covering wider range of the mammalian NLSs in
Ryosuke Yamagishi, Hiroki Kaneko
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Effect of Different Nuclear Localization Signals on the Subcellular Localization and Anti-HIV-1 Function of the MxB Protein [PDF]
Frontiers in Microbiology, 2021 Interferon exerts its antiviral activity by stimulating the expression of antiviral proteins. These interferon stimulate genes (ISGs) often target a group of viruses with unique molecular mechanisms.
Keli Chai +10 more
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Origin of the nuclear proteome on the basis of pre-existing nuclear localization signals in prokaryotic proteins [PDF]
Biology Direct, 2020 Background The origin of the selective nuclear protein import machinery, which consists of nuclear pore complexes and adaptor molecules interacting with the nuclear localization signals (NLSs) of cargo molecules, is one of the most important events in ...
Olga M. Lisitsyna +6 more
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Identification and Functional Analysis of Dual Nuclear Localization Signals on Desmin [PDF]
ACS OmegaEcem KURAL MANGIT, Pervin DİNÇER
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