Results 21 to 30 of about 226,269 (286)

Identification and Functional Analysis of Dual Nuclear Localization Signals on Desmin [PDF]

ACS Omega
Ecem KURAL MANGIT, Pervin DİNÇER
doaj   +2 more sources

Insights into the origin of the nuclear localization signals in conserved ribosomal proteins [PDF]

Nat Commun, 2015
Sergey Melnikov, Adam Ben‐Shem, G. Yusupova, Marat Yusupov   +3 more
openalex   +2 more sources

Nuclear dynamics: Formation of bodies and trafficking in plant nuclei

Frontiers in Plant Science, 2022
The existence of the nucleus distinguishes prokaryotes and eukaryotes. Apart from containing most of the genetic material, the nucleus possesses several nuclear bodies composed of protein and RNA molecules.
Eduardo Muñoz-Díaz, Eduardo Muñoz-Díaz, Julio Sáez-Vásquez, Julio Sáez-Vásquez   +3 more
doaj   +1 more source

Evolution Analysis of the Aux/IAA Gene Family in Plants Shows Dual Origins and Variable Nuclear Localization Signals [PDF]

International Journal of Molecular Sciences, 2017
Haoli Ma, Wang Yuqian, Ma Haoli
exaly   +2 more sources

NLSdb: database of nuclear localization signals [PDF]

Nucleic Acids Research, 2003
NLSdb is a database of nuclear localization signals (NLSs) and of nuclear proteins. NLSs are short stretches of residues mediating transport of nuclear proteins into the nucleus. The database contains 114 experimentally determined NLSs that were obtained through an extensive literature search.
Rajesh Nair, Phil Carter, Burkhard Rost
openaire   +2 more sources

Cooperative nuclear localization sequences lend a novel role to the N-terminal region of MSH6. [PDF]

PLoS ONE, 2011
Human mismatch repair proteins MSH2-MSH6 play an essential role in maintaining genetic stability and preventing disease. While protein functions have been extensively studied, the substantial amino-terminal region (NTR*) of MSH6 that is unique to ...
Natalie R Gassman, Jill E Clodfelter, Anita K McCauley, Keith Bonin, Freddie R Salsbury, Karin D Scarpinato   +5 more
doaj   +1 more source

Modular organization and combinatorial energetics of proline-tyrosine nuclear localization signals. [PDF]

PLoS Biology, 2008
Proline-tyrosine nuclear localization signals (PY-NLSs) are recognized and transported into the nucleus by human Karyopherin (Kap) beta2/Transportin and yeast Kap104p.
Katherine E Süel, Hongmei Gu, Yuh Min Chook   +2 more
doaj   +1 more source

Nucleoplasmic signals promote directed transmembrane protein import simultaneously via multiple channels of nuclear pores

Nature Communications, 2020
The contribution of central and peripheral channels of nuclear pores to transport of transmembrane proteins is unclear. Here the authors show that most inner nuclear membrane proteins use only peripheral channels, but some extend nuclear localization ...
Krishna C. Mudumbi, Rafal Czapiewski, Andrew Ruba, Samuel L. Junod, Yichen Li, Wangxi Luo, Christina Ngo, Valentina Ospina, Eric C. Schirmer, Weidong Yang   +9 more
doaj   +1 more source

Parafibromin is a nuclear protein with a functional monopartite nuclear localization signal [PDF]

Oncogene, 2006
Parafibromin is a nuclear protein with a tumour suppressor role in the development of non-hereditary and hereditary parathyroid carcinomas, and the hyperparathyroidism-jaw tumour (HPT-JT) syndrome, which is associated with renal and uterine tumours. Nuclear localization signal(s), (NLS(s)), of the 61 kDa parafibromin remain to be defined.
Bradley, K, Bowl, MR, Williams, SE, Ahmad, B, Partridge, C, Patmanidi, A, Kennedy, A, Loh, N, Thakker, R   +8 more
openaire   +3 more sources

Mechanisms Mediating Nuclear Trafficking Involved in Viral Propagation by DNA Viruses

Viruses, 2019
Typical viral propagation involves sequential viral entry, uncoating, replication, gene transcription and protein synthesis, and virion assembly and release. Some viral proteins must be transported into host nucleus to facilitate viral propagation, which
Guohui Li, Xinyu Qi, Zhaoyang Hu, Qi Tang   +3 more
doaj   +1 more source