Results 41 to 50 of about 226,269 (286)
Scientific Reports, 2019 Transcription factor 4 (TCF4) is a class I basic helix-loop-helix (bHLH) transcription factor which regulates the neurogenesis and specialization of cells.
Beata Greb-Markiewicz +3 more
doaj +1 more source
BioTechniques, 1999 We established a straightforward experimental system to investigate directly the requirements for nucleocytoplasmic transport in live cells. For this purpose, substrates were created containing nuclear localization signals (NLS) or nuclear export signals
O. Rosorius +5 more
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Pentapeptide Nuclear Localization Signal in Adenovirus E1a [PDF]
Molecular and Cellular Biology, 1987 The adenovirus E1a gene products are nuclear proteins important in transcriptional control of viral functions during infection. By producing normal E1a proteins and derivatives of E1a in bacteria and microinjecting these proteins into cultured cells, we were able to examine their ability to localize to the nucleus.
R H, Lyons, B Q, Ferguson, M, Rosenberg
openaire +2 more sources
Two nuclear localization signals in USP1 mediate nuclear import of the USP1/UAF1 complex.
PLoS ONE, 2012 The human deubiquitinase USP1 plays important roles in cancer-related processes, such as the DNA damage response, and the maintenance of the undifferentiated state of osteosarcoma cells.
Iraia Garcia-Santisteban +2 more
doaj +1 more source
Two nuclear localization signals are required for nuclear translocation of nuclear factor 1‐A [PDF]
FEBS Letters, 2000 Nuclear factor 1 (NF1) proteins are encoded by at least four genes (NF1‐A, B, C, X). Although DNA‐binding and the transcription regulation domains of these proteins are well characterized, the nuclear localization signals (NLSs) are still unknown in all NF1s.
Imagawa, Masayoshi +4 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
BMC Bioinformatics, 2012 Background Identification of subcellular localization in proteins is crucial to elucidate cellular processes and molecular functions in a cell. However, given a tremendous amount of sequence data generated in the post-genomic era, determining protein ...
Su Emily +4 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger +7 more
wiley +1 more source
The Cell Cycle Independence of HIV Infections Is Not Determined by Known Karyophilic Viral Elements. [PDF]
PLoS Pathogens, 2005 Human immunodeficiency virus and other lentiviruses infect cells independent of cell cycle progression, but gammaretroviruses, such as the murine leukemia virus (MLV) require passage of cells through mitosis.
Masahiro Yamashita, Michael Emerman
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Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations
Pediatric Blood &Cancer, EarlyView.ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan +18 more
wiley +1 more source