Results 41 to 50 of about 270,346 (298)

Identification of Sequences Encoding Symbiodinium minutum Mitochondrial Proteins. [PDF]

, 2016
The dinoflagellates are an extremely diverse group of algae closely related to the Apicomplexa and the ciliates. Much work has previously been undertaken to determine the presence of various biochemical pathways within dinoflagellate mitochondria ...
Butterfield, Erin R., Howe, Christopher J., Nisbet, R. Ellen R.   +2 more
core   +4 more sources

p53 stabilization: the importance of nuclear import [PDF]

Cell Death & Differentiation, 2010
In response to cellular stress, the p53 tumor suppressor protein is stabilized as a result of inactivation of ubiquitin-mediated degradation. The p53 protein rapidly accumulates in the nucleus, where it functions as a transcription factor. Although the regulation of p53 stability has been studied extensively, the subcellular compartment in which p53 ...
openaire   +2 more sources

Inhibition of HIV-1 integrase nuclear import and replication by a peptide bearing integrase putative nuclear localization signal

Retrovirology, 2009
Background The integrase (IN) of human immunodeficiency virus type 1 (HIV-1) has been implicated in different steps during viral replication, including nuclear import of the viral pre-integration complex.
Waigmann Elisabeth, Graessmann Adolf, Melamed-Book Naomi, Rosenbluh Joseph, Armon-Omer Ayelet, Levin Aviad, Loyter Abraham   +6 more
doaj   +1 more source

Conservation of complex nuclear localization signals utilizing classical and non-classical nuclear import pathways in LANA homologs of KSHV and RFHV. [PDF]

PLoS ONE, 2011
ORF73 latency-associated nuclear antigen (LANA) of the Kaposi's sarcoma-associated herpesvirus (KSHV) is targeted to the nucleus of infected cells where it binds to chromatin and mediates viral episome persistence, interacts with cellular proteins and ...
Lidia Cherezova, Kellie L Burnside, Timothy M Rose   +2 more
doaj   +1 more source

The gateway to chloroplast: re-defining the function of chloroplast receptor proteins [PDF]

, 2012
Chloroplast biogenesis often requires a tight orchestration between gene expression (both plastidial and nuclear) and translocation of similar to 3000 nuclear-encoded proteins into the organelle.
Bölter, Bettina, Chang, Wai-Ling, Soll, Jürgen   +2 more
core   +1 more source

Speeding nuclear import [PDF]

The Journal of Cell Biology, 2006
![Graphic][1] Import time (red) decreases and efficiency (blue) increases with more importin β. Faster, better import is gained by increasing levels of the importin β nuclear transport receptor, according to Yang and Musser (page [951][2]).
openaire   +1 more source

Altering the levels of nuclear import factors in early Xenopus laevis embryos affects later development.

PLoS ONE, 2019
More than just a container for DNA, the nuclear envelope carries out a wide variety of critical and highly regulated cellular functions. One of these functions is nuclear import, and in this study we investigate how altering the levels of nuclear ...
Predrag Jevtić, Richik N Mukherjee, Pan Chen, Daniel L Levy   +3 more
doaj   +1 more source

Targeting nuclear transporters in cancer: Diagnostic, prognostic and therapeutic potential [PDF]

, 2016
The Karyopherin superfamily is a major class of soluble transport receptors consisting of both import and export proteins. The trafficking of proteins involved in transcription, cell signalling and cell cycle regulation among other functions across the ...
Aggarwal, Albee, Alnabulsi, Alshareeda, Altan, Angus, Behrens, Bernis, Blower, Brinkmann, Brinkmann, Cansizoglu, Chang, Christiansen, Dahl, Das, Dasso, Depping, Dikovskaya, Forbes, Gluz, Gontan, Gorlich, Gousias, Gousias, Gousias, Grupp, Gruss, Hashimoto, Hintersteiner, Hu, Huang, Huang, Huang, Hutchins, Hügel, Ishizawa, Jensen, Jiang, Kahle, Kau, Kazim, Kim, Kimura, King, Knauer, Kojima, Kosugi, Kudo, Kurisaki, Kutay, Kuusisto, Kuusisto, Lapalombella, Latvia, Lau, Laurila, Li, Liang, Liao, Lin, Lin, Lorenzato, Ma, Marfori, Martens-de Kemp, Melo, Mortezavi, Mosammaparast, Muller, Nevins, Noske, Parikh, Poon, Pumroy, Quan, Quensel, Rensen, Sakai, Scherf, Shen, Shi, Shiraki, Sillje, Smith, Smith, Soderholm, Song, Stawerski, Stella Tsai, Stewart, Tai, Torgerson, Turner, Turner, Wagstaff, Wang, Wang, Wang, Watt, Watt, Watt, Wellmann, Wiese, Winkler, Winnepenninckx, Wu, Yan, Yang, Yao, Yoshitake, Yu, Zender, Zheng, Zhou, Zhu, Zhu, Zienkiewicz   +117 more
core   +1 more source

Overlapping nuclear import and export paths unveiled by two-colour MINFLUX. [PDF]

Nature
Sau A, Schnorrenberg S, Huang Z, Bandyopadhyay D, Sharma A, Gürth CM, Dave S, Musser SM.   +7 more
europepmc   +2 more sources

GAP activity, but not subcellular targeting, is required for Arabidopsis RanGAP cellular and developmental functions [PDF]

, 2015
The Ran GTPase activating protein (RanGAP) is important to Ran signaling involved in nucleocytoplasmic transport, spindle organization, and postmitotic nuclear assembly.
Boruc, Joanna, Griffis, Anna HN, Meier, Iris, Rodrigo-Peiris, Thushani, Tilford, Bailey, Van Damme, Daniël, Zhou, Xiao   +6 more
core   +2 more sources