Results 31 to 40 of about 270,346 (298)

A morphological view on mitochondrial protein targeting [PDF]

, 1994
Mitochondrial protein targeting includes both intramitochondrial sorting of proteins encoded by the organellar genome and import and subsequent sorting of nuclear encoded precursor proteins. Only a few proteins are encoded by the mitochondrial genome and
Ades, Allmann, Ardail, Ardail, Ardail, Attardi, Baker, Biermans, Biermans, Brdiczka, Brdiczka, Eilers, Glick, Hackenbrock, Hackenbrock, Hackenbrock, Hartl, Hartl, Hines, Hwang, Kellems, Kiebler, Knoll, Lill, Lithgow, Malhotra, Martin, Marzuki, McEnery, Murakami, Nicolay, Ohlendieck, Pain, Pfanner, Pfanner, Pfanner, Pon, Rassow, Rassow, Rassow, Rojo, Schleyer, Schwaiger, Stuart, Suissa, Söllner, Söllner, Söllner, van Venetië, Vestweber, Vestweber, Vignais, Watson, Werner, Wienhues, Zara   +55 more
core   +1 more source

The protein import apparatus of chloroplasts [PDF]

, 1993
Routing of cytosolically synthesized precursor proteins into chloroplasts is a specific process which involves a multitude of soluble and membrane components.
Bartling D., Bassham D. C., Buvinger W. E., Cline K., Cline K., Cline K., Heike Alefsen, Joyard J., Jürgen Soll, Kirwin P. M., Li H.‐M., Mould R. M., Olsen L. J., Olsen L. J., Perry S. E., Pilon M., Schnell D. J., Theg S. M.   +17 more
core   +1 more source

Molecular determinants of large cargo transport into the nucleus

eLife, 2020
Nucleocytoplasmic transport is tightly regulated by the nuclear pore complex (NPC). Among the thousands of molecules that cross the NPC, even very large (>15 nm) cargoes such as pathogens, mRNAs and pre-ribosomes can pass the NPC intact.
Giulia Paci, Tiantian Zheng, Joana Caria, Anton Zilman, Edward A Lemke   +4 more
doaj   +1 more source

The nuclear entry of the aryl hydrocarbon receptor (AHR) relies on the first nuclear localization signal and can be negatively regulated through IMPα/β specific inhibitors

Scientific Reports, 2023
The human aryl hydrocarbon receptor (AHR) undergoes continuous shuttling between nucleus and cytoplasm. Binding to exogenous or endogenous ligands promotes its rapid nuclear import.
Rashad Haidar, Reneh Shabo, Marie Moeser, Andreas Luch, Josephine Kugler   +4 more
doaj   +1 more source

p34cdc2-mediated phosphorylation at T124 inhibits nuclear import of SV-40 T antigen proteins [PDF]

, 1991
The nuclear import of transcription regulatory proteins appears to be used by the cell to trigger transitions in cell cycle, morphogenesis, and transformation.
Ackermann, M. J., Beach, D. H., Bischoff, J. R., Jans, D. A., Peters, R.   +4 more
core   +1 more source

Nuclear import of influenza A viral ribonucleoprotein complexes is mediated by two nuclear localization sequences on viral nucleoprotein

Virology Journal, 2007
Background The influenza A virus replicates in the nucleus of its host cell. Thus, entry of the influenza genome into the cell nucleus is necessary for establishing infection.
Panté Nelly, Sun Ying-Hua B, Wu Winco WH   +2 more
doaj   +1 more source

Transportin-1: A Nuclear Import Receptor with Moonlighting Functions

Frontiers in Molecular Biosciences, 2021
Transportin-1 (Trn1), also known as karyopherin-β2 (Kapβ2), is probably the best-characterized nuclear import receptor of the karyopherin-β family after Importin-β, but certain aspects of its functions in cells are still puzzling or are just recently ...
Allegra Mboukou, Vinod Rajendra, Renata Kleinova, Carine Tisné, Michael F. Jantsch, Pierre Barraud   +5 more
doaj   +1 more source

Cell biological mechanisms of activity-dependent synapse to nucleus translocation of CRTC1 in neurons. [PDF]

, 2015
Previous studies have revealed a critical role for CREB-regulated transcriptional coactivator (CRTC1) in regulating neuronal gene expression during learning and memory. CRTC1 localizes to synapses but undergoes activity-dependent nuclear translocation to
Ch'ng, Toh Hean, DeSalvo, Martina, Lin, Peter, Martin, Kelsey C, Vashisht, Ajay, Wohlschlegel, James A   +5 more
core   +1 more source

Protoparvovirus Knocking at the Nuclear Door

Viruses, 2017
Protoparvoviruses target the nucleus due to their dependence on the cellular reproduction machinery during the replication and expression of their single-stranded DNA genome.
Elina Mäntylä, Michael Kann, Maija Vihinen-Ranta   +2 more
doaj   +1 more source

Dynamics of the STAT3 transcription factor: nuclear import dependent on Ran and importin-β1. [PDF]

PLoS ONE, 2011
The signal transducer and activator of transcription-3 (STAT3) induces transcription of genes that control differentiation, inflammation, proliferation, and tumor cell invasion.
Velasco Cimica, Hui-Chen Chen, Janaki K Iyer, Nancy C Reich   +3 more
doaj   +1 more source