Results 31 to 40 of about 75,707 (295)

UV-induced nuclear import of XPA is mediated by importin-α4 in an ATR-dependent manner. [PDF]

PLoS ONE, 2013
Xeroderma pigmentosum Group A (XPA) is a crucial factor in mammalian nucleotide excision repair (NER) and nuclear import of XPA from the cytoplasm for NER is regulated in cellular DNA damage responses in S-phase.
Zhengke Li, Phillip R Musich, Brian M Cartwright, Hui Wang, Yue Zou   +4 more
doaj   +1 more source

PP2A Regulates HDAC4 Nuclear Import [PDF]

Molecular Biology of the Cell, 2008
Different signal-regulated serine/threonine kinases phosphorylate class II histone deacetylases (HDACs) to promote nuclear export, cytosolic accumulation, and activation of gene transcription. However, little is known about mechanisms operating in the opposite direction, which, possibly through phosphatases, should promote class II HDACs nuclear entry ...
BRANCOLINI, Claudio, CERNOTTA, Nadia, DELLO RUSSO C., FOTI, Carmela, GALLINARI P, ORSATTI L., PALLAORO M., PARONI, Gabriela, STEINKUHLER C, TALAMO F.   +9 more
openaire   +3 more sources

Molecular determinants of large cargo transport into the nucleus

eLife, 2020
Nucleocytoplasmic transport is tightly regulated by the nuclear pore complex (NPC). Among the thousands of molecules that cross the NPC, even very large (>15 nm) cargoes such as pathogens, mRNAs and pre-ribosomes can pass the NPC intact.
Giulia Paci, Tiantian Zheng, Joana Caria, Anton Zilman, Edward A Lemke   +4 more
doaj   +1 more source

Neutrino Interactions Importance to Nuclear Physics [PDF]

AIP Conference Proceedings, 2009
To appear in the proceedings of 6th International Workshop on Neutrino-Nucleus Interactions in the Few-GeV Region (NuInt09), Sitges, Spain, 18 - 22 May ...
J. E. Amaro, C. Maieron, M. Valverde, J. Nieves, M. B. Barbaro, J. A. Caballero, T. W. Donnelly, J. M. Udias, Federico Sanchez, M. Sorel, Luis Alvarez-Ruso   +10 more
openaire   +4 more sources

Nuclear import of influenza A viral ribonucleoprotein complexes is mediated by two nuclear localization sequences on viral nucleoprotein

Virology Journal, 2007
Background The influenza A virus replicates in the nucleus of its host cell. Thus, entry of the influenza genome into the cell nucleus is necessary for establishing infection.
Panté Nelly, Sun Ying-Hua B, Wu Winco WH   +2 more
doaj   +1 more source

The nuclear entry of the aryl hydrocarbon receptor (AHR) relies on the first nuclear localization signal and can be negatively regulated through IMPα/β specific inhibitors

Scientific Reports, 2023
The human aryl hydrocarbon receptor (AHR) undergoes continuous shuttling between nucleus and cytoplasm. Binding to exogenous or endogenous ligands promotes its rapid nuclear import.
Rashad Haidar, Reneh Shabo, Marie Moeser, Andreas Luch, Josephine Kugler   +4 more
doaj   +1 more source

Transportin-1: A Nuclear Import Receptor with Moonlighting Functions

Frontiers in Molecular Biosciences, 2021
Transportin-1 (Trn1), also known as karyopherin-β2 (Kapβ2), is probably the best-characterized nuclear import receptor of the karyopherin-β family after Importin-β, but certain aspects of its functions in cells are still puzzling or are just recently ...
Allegra Mboukou, Vinod Rajendra, Renata Kleinova, Carine Tisné, Michael F. Jantsch, Pierre Barraud   +5 more
doaj   +1 more source

Functional specialization amongst the Arabidopsis Toc159 family of chloroplast protein import receptors [PDF]

, 2004
The initial stages of preprotein import into chloroplasts are mediated by the receptor GTPase Toc159. In Arabidopsis thaliana, Toc159 is encoded by a small gene family: atTOC159, atTOC132, atTOC120, and atTOC90.
Jocelyn Beédard, Jonathan Combe, Lilley, Kathryn, Leister, D., Rios, Gabino, Kubis, Sybille, Koncz, Csaba, Combe, J., Bedard, J., Paul Jarvis, Rios, G., Sybille Kubis, Patel, R., Kovacheva, S., Lilley, K., Kubis, S., Leister, Dario, Combe, Jonathan, Bédard, Jocelyn, Jarvis, Paul, Dario Leister, Biehl, A., Sabina Kovacheva, Kovacheva, Sabina, Kathryn Lilley, Alexander Biehl, Jarvis, P., Ramesh Patel, Patel, Ramesh, Koncz, C., Csaba Koncz, Biehl, Alexander, Gabino Riéos   +32 more
core   +1 more source

The Arabidopsis ppi1 mutant is specifically defective in the expression, chloroplast import, and accumulation of photosynthetic proteins [PDF]

, 2003
The import of nucleus-encoded proteins into chloroplasts is mediated by translocon complexes in the envelope membranes. A component of the translocon in the outer envelope membrane, Toc34, is encoded in Arabidopsis by two homologous genes, atTOC33 and ...
Baldwin, Amy, Lilley, Kathryn, Leister, D., Kubis, Sybille, Kurth, Joachim, Kurth, J., Paul Dupree, Baldwin, Amy Joy, Razzaq, A., Dupree, Paul, Baldwin, A., Paul Jarvis, Sybille Kubis, Patel, R., Lilley, K., Azam Razzaq, Kubis, S., Leister, Dario, Amy Baldwin, Jarvis, Paul, Razzaq, Azam, Dario Leister, Kathryn Lilley, Jarvis, P., Dupree, P., Ramesh Patel, Joachim Kurth, Patel, Ramesh   +27 more
core   +1 more source

Protoparvovirus Knocking at the Nuclear Door

Viruses, 2017
Protoparvoviruses target the nucleus due to their dependence on the cellular reproduction machinery during the replication and expression of their single-stranded DNA genome.
Elina Mäntylä, Michael Kann, Maija Vihinen-Ranta   +2 more
doaj   +1 more source